Abrupt closure

Overview
Abrupt closure is defined as the development of TIMI grade 0 or 1 flow during percutaneous coronary intervention (PCI). If a patient begins the procedure with TIMI grade 0 or 1 flow, the term abrupt closure is applied if during some point in the procedure there was restoration of TIMI grade 3, which was followed by a recurrence of TIMI grade 0 or 1 flow.