6-oxohexanoate dehydrogenase

In enzymology, a 6-oxohexanoate dehydrogenase is an enzyme that catalyzes the chemical reaction


 * 6-oxohexanoate + NADP+ + H2O $$\rightleftharpoons$$ adipate + NADPH + 2 H+

The 3 substrates of this enzyme are 6-oxohexanoate, NADP+, and H2O, whereas its 3 products are adipate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 6-oxohexanoate:NADP+ oxidoreductase. This enzyme participates in caprolactam degradation.