1-acylglycerophosphocholine O-acyltransferase

In enzymology, a 1-acylglycerophosphocholine O-acyltransferase is an enzyme that catalyzes the chemical reaction


 * acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine $$\rightleftharpoons$$ CoA + 1,2-diacyl-sn-glycero-3-phosphocholine

Thus, the two substrates of this enzyme are acyl-CoA and 1-acyl-sn-glycero-3-phosphocholine, whereas its two products are CoA and 1,2-diacyl-sn-glycero-3-phosphocholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase. Other names in common use include lysolecithin acyltransferase, 1-acyl-sn-glycero-3-phosphocholine acyltransferase, acyl coenzyme A-monoacylphosphatidylcholine acyltransferase, acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase, lysophosphatide acyltransferase, and lysophosphatidylcholine acyltransferase. This enzyme participates in glycerophospholipid metabolism.