Prostatic intraepithelial neoplasia

Overview
Prostatic intraepithelial neoplasia (PIN) is a non-invasive lesion in the prostate gland which is though to be a precursor to prostate cancer. Microscopically, PIN is a collection of irregular cells which are fully contained within the gland structure and have not spread to the surrounding tissue. This may be proven by the identification of basal cells forming the supporting layer of the gland. PIN does not require specific therapy, but close follow-up with additional biopsies is warranted. PIN may disappear, remain unchanged, or progress to prostate cancer, often over as many as ten years.

Histopathological Findings: Intraepithelial Neoplasia (PIN)
