Alpha-tubulin N-acetyltransferase

In enzymology, an alpha-tubulin N-acetyltransferase is an enzyme that catalyzes the chemical reaction


 * acetyl-CoA + [alpha-tubulin]-L-lysine $$\rightleftharpoons$$ CoA + [alpha-tubulin]-N6-acetyl-L-lysine

Thus, the two substrates of this enzyme are acetyl-CoA and [alpha-tubulin]-L-lysine, whereas its two products are CoA and [alpha-tubulin]-N6-acetyl-L-lysine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:[alpha-tubulin]-L-lysine N6-acetyltransferase. Other names in common use include alpha-tubulin acetylase, TAT, alpha-tubulin acetyltransferase, tubulin N-acetyltransferase, acetyl-CoA:alpha-tubulin-L-lysine N-acetyltransferase, and acetyl-CoA:[alpha-tubulin]-L-lysine 6-N-acetyltransferase.