Oleoyl-(acyl-carrier-protein) hydrolase

In enzymology, an oleoyl-[acyl-carrier-protein] hydrolase is an enzyme that catalyzes the chemical reaction


 * oleoyl-[acyl-carrier-protein] + H2O $$\rightleftharpoons$$ [acyl-carrier-protein] + oleate

Thus, the two substrates of this enzyme are oleoyl-[acyl-carrier-protein] and H2O, whereas its two products are [acyl-carrier-protein] and oleate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is oleoyl-[acyl-carrier-protein] hydrolase. Other names in common use include acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, and oleoyl-acyl carrier protein thioesterase. This enzyme participates in fatty acid biosynthesis.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.