Fructose-2,6-bisphosphate 2-phosphatase

In enzymology, a fructose-2,6-bisphosphate 2-phosphatase is an enzyme that catalyzes the chemical reaction


 * beta-D-fructose 2,6-bisphosphate + H2O $$\rightleftharpoons$$ D-fructose 6-phosphate + phosphate

Thus, the two substrates of this enzyme are beta-D-fructose 2,6-bisphosphate and H2O, whereas its two products are D-fructose 6-phosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase. Other names in common use include fructose-2,6-bisphosphatase, and D-fructose-2,6-bisphosphate 2-phosphohydrolase. This enzyme participates in fructose and mannose metabolism.

Structural studies
As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , , and.