Dextro-transposition of the great arteries differential diagnosis


 * Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [mailto:psingh@perfuse.org]; ; Keri Shafer, M.D. [mailto:kshafer@bidmc.harvard.edu]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [mailto:kfeeney@perfuse.org]

Overview
Patients with dextro-transposition of the great arteries should be differentiated from other cardiac and non-cardiac causes of cyanosis-

Differential diagnosis
Cardiac causes (starts with 't')- Other less common causes are- pulmonary atresia, hypoplastic left heart syndrome, anomalous systemic venous connection. Non-cardiac causes
 * Tetralogy of Fallot
 * Truncus arteriosus
 * Total anomalous pulmonary venous connection
 * Other tricuspid valve abnormalities like tricuspid regurgitaton, tricuspid stenosis
 * Pulmonary diseases - Structural abnormalities of the lung, V/P (ventilation-perfusion mismatch), airway obstruction, pneumothorax, and hypoventilation.
 * Abnormal hemoglobin like methemoglobin, polycythemia
 * Peripheral cyanosis for e.g. sepsis, hypoglycemia, dehydration, and hypoadrenalism.