4-chlorobenzoate dehalogenase

In enzymology, a 4-chlorobenzoate dehalogenase is an enzyme that catalyzes the chemical reaction


 * 4-chlorobenzoate + H2O $$\rightleftharpoons$$ 4-hydroxybenzoate + chloride

Thus, the two substrates of this enzyme are 4-chlorobenzoate and H2O, whereas its two products are 4-hydroxybenzoate and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is 4-chlorobenzoate chlorohydrolase. This enzyme is also called halobenzoate dehalogenase.

Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes, , and.