Talk:HIV vaccine

The text above was taken from the NIAID document "HIV Vaccine Development Status Report May 2000" taken from http://www.niaid.nih.gov/daids/vaccine/whsummarystatus.htm which, as a work of a US Federal Government agency without any other copyright notice, should be in the public domain

Microbicides
Can someone add to the AIDS catagory microbicides? They are usually intervaginal substances (gels, cremes, sprays) that disable the HIV virus. It is an interesting new avenue towards fighting aids.

they are always lookin for new ways to protect themselves from death even if it involves --168.171.206.4 18:15, 6 March 2006 (UTC)

--ShaunMacPherson 23:05, 27 Jun 2004 (UTC)

Vaccine effectiveness
Is there any information out there on whether the vaccines will work as well on people who have already been infected with the virus?

YES. see the article below about Dr Abalaka's Vaccine in Nigeria.You are equally encouraged to read the mentioned publication yourself. Indivisuals on the treatment have been reported to be cured.

Missing Text on This Page
The paragraph that begins "The availability of several recombinant canarypox..." is incomplete. It ends with a dependent clause and ends with a comma. Something is missing here. DanMS 00:27, 16 Jun 2005 (UTC) A vaccine has been proved to be safe and effective in Nigeria

Vaccine development
A recent article paints a gloomy picture, quote: "Many experts admit that despite intensive global efforts, an HIV/AIDS vaccine remains elusive, and might never be found." --Vsion 07:03, 1 October 2005 (UTC)

Clarification
"However, the classical vaccination approaches that have been successful in the control of various viral diseases by priming the adaptive immunity to recognise the viral envelope proteins have failed in the case of HIV-1, as the epitopes of the viral envelope are too variable. Furthermore, the functionally important epitopes of the gp120 protein are masked by glycosylation, trimerisation and receptor-induced conformational changes making it difficult to block with neutralising antibodies."

While very well written, this paragraph is not very lucid to the lay reader such as my self, I would like to see it expanded if someone with the appropriate knowledge would take the time.

There is every reason to believe that a Nigerian Medical doctor (Dr J.O. Abalaka) has developed a vaccine against HIV.Please reference the journal 'VACCINE' of July 2004:pp 3819-28. It does appear to me that The UN Director on HIV Dr Peter Piott has succeded in cajoling every government agency to believe in the US multinationals believe that HIV vaccine can only be developed in the West. This type of stereotype cannot help in finding solution to the problem of HIV vaccine development.US and other drug companies have succeded in taking over and controlling the UN agency on HIV including the Director who appears to be on their payroll.There is the need to address the issue of involvement of drug companies in UN works particularly on the issue of HIV. Elijah

Severe cutdown of the section on HAART
Is there any reason we need to spend two paragraphs discussing HAART in the introduction? Would anybody mind if I gave this a serious trim-down?

Furthermore, does this article really need to use so much medical terminology? Think of your readership...--Robert Merkel 01:56, 25 May 2006 (UTC)

economics section

 * A June 2005 study estimates that $682 million is spent on AIDS vaccine research annually.

It would be useful to the section to contrast this with drug company profits from AIDS drugs, if such data can be found or if someone can be quoted with an estimate. This obviously must be done in an NPOV way; my goal is not to cast drug companies as villains in a drama (and I personally have no idea which way the comparison even goes). Tempshill 23:23, 22 August 2006 (UTC)
 * Of course (!?) an AIDS vaccine would reduce or destroy profits from AIDS drugs.... Rich Farmbrough, 13:58 16 October 2006 (GMT).

What's with the numbers in the text? It looks like copy&paste without copying the footnotes.

POV and omniscience (crystal ball)
Theres a bit of this in the article, about what is "needed" an "demanded", and what the consequences of various hypothetical discoveries will be. I've changed a bit but I think there's more. Rich Farmbrough, 13:58 16 October 2006 (GMT).

NEJM article
There is an interesting review about HIV vaccines in this week's NEJM that could be useful for this article:

--WS 19:19, 21 May 2007 (UTC)