Idebenone

Idebenone (pronounced eye-deb-eh-known) is an organic compound of the quinone family and promoted commercially as a synthetic analog of Coenzyme Q10 (CoQ10).

Idebenone is claimed to have properties similar to CoQ10 in its antioxidant properties.

Idebenone is different from Coenzyme Q10 in one very important way. During a hypoxic (low oxygen) condition, CoQ10 can switch function from an anti-oxidizing to an auto-oxidizing process. This auto-oxidation rapidly produces free radicals which damage the tissues of the body.

Idebenone is said to perform the same functions as CoQ10 without the risk of an auto-oxidation reaction.

Idebenone is said to promote NGF (nerve growth factor) in the brain. It appears to reduce tinnitus (ringing in the ears). Idebenone has also been used in topical applications to treat wrinkles.

Takeda Pharmaceuticals studied Idebenone which it got approved for Alzheimer's disease and Stroke.

Idebenone has reduced the rate of deterioration of cardiac function in patients with Friedreich's ataxia (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=12771265&ordinalpos=14&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)