Hepatitis C physical examination

Clinical Findings According to Disease Stages

 * Acute
 * Mild or absent symptoms (7-8 weeks after exposure)
 * Chronic
 * Fatigue
 * Late Complications
 * Cirrhosis
 * Hepatocellular carcinoma (HCC) in cirrhotics (1-4%/year)
 * Extrahepatic Symptoms
 * Cryoglobulinemia (~50%)
 * Only 10-15% of patients with +cryos have symptoms
 * Symptoms
 * Arthralgias
 * Weakness
 * Purpura
 * Membranoproliferative glomerulonephritis (MPGN)
 * Pruritus, psoriasis, Raynaud’s phenomenon (6-20%)
 * Sicca syndrome (10-12%)
 * Neuropathy (5-9%)
 * Porphyria cutanea tarda (PCT), lichen planus (1%)