Chondroitin-glucuronate 5-epimerase

In enzymology, a chondroitin-glucuronate 5-epimerase is an enzyme that catalyzes the chemical reaction


 * chondroitin D-glucuronate $$\rightleftharpoons$$ dermatan L-iduronate

Hence, this enzyme has one substrate, chondroitin D-glucuronate, and one product, dermatan L-iduronate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is chondroitin-D-glucuronate 5-epimerase. Other names in common use include polyglucuronate 5-epimerase, dermatan-sulfate 5-epimerase, urunosyl C-5 epimerase, and chondroitin D-glucuronosyl 5-epimerase. This enzyme participates in chondroitin sulfate biosynthesis.