Glucose-fructose oxidoreductase

In enzymology, a glucose-fructose oxidoreductase is an enzyme that catalyzes the chemical reaction


 * D-glucose + D-fructose $$\rightleftharpoons$$ D-gluconolactone + D-glucitol

Thus, the two substrates of this enzyme are D-glucose and D-fructose, whereas its two products are D-gluconolactone and D-glucitol.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-glucose:D-fructose oxidoreductase.

Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , and.