D-octopine dehydrogenase

In enzymology, a D-octopine dehydrogenase is an enzyme that catalyzes the chemical reaction


 * N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O $$\rightleftharpoons$$ L-arginine + pyruvate + NADH + H+

The 3 substrates of this enzyme are N2-(D-1-carboxyethyl)-L-arginine, NAD+, and H2O, whereas its 4 products are L-arginine, pyruvate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming). Other names in common use include D-octopine synthase, octopine dehydrogenase, octopine:NAD+ oxidoreductase, ODH, 2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase, and (L-arginine-forming). This enzyme participates in arginine and proline metabolism.