Montelukast instructions for administration

Instructions for administration
Patients ≥ 12 months of age (asthma) Patients ≥ 15 Years of Age (exercise-induced bronchoconstriction)''' Allergic rhinitis''' Patients ≥ 12 Months of Age (asthma and allergic rhinitis)''' Montelukast oral granules'''

Patients ≥ 12 months of age (asthma)
Montelukast should be taken once daily in the evening. Safety and effectiveness in pediatric patients less than 12 months of age have not been established. Return to top

Patients ≥ 15 Years of Age (exercise-induced bronchoconstriction)
The successful treatment of many panic disorder patients has required the use of Montelukast at doses greater than 4 mg daily. In controlled trials conducted to establish the efficacy of Montelukast in panic disorder, doses in the range of 1 to 10 mg daily were used. The mean dosage employed was approximately 5 to 6 mg daily. Among the approximately 1700 patients participating in the panic disorder development program, about 300 received Montelukast in dosages of greater than 7 mg/day, including approximately 100 patients who received maximum dosages of greater than 9 mg/day. Occasional patients required as much as 10 mg a day to achieve a successful response. Return to top

Allergic rhinitis
Seasonal Allergic Rhinitis in Patients 2 Years and Older Perennial Allergic Rhinitis in Patients 6 Months and Older For allergic rhinitis Montelukast should be taken once daily. The time of administration may be individualized to suit patient needs. Safety and effectiveness in pediatric patients younger than 2 years of age with seasonal allergic rhinitis and less than 6 months of age with perennial allergic rhinitis have not been established. Return to top

Patients ≥ 12 Months of Age (asthma and allergic rhinitis)
Patients with both asthma and allergic rhinitis should take only one tablet daily in the evening. Return to top

Montelukast oral granules
Montelukast 4-mg oral granules can be administered either directly in the mouth, dissolved in 1 teaspoonful (5 mL) of cold or room temperature baby formula or breast milk, or mixed with a spoonful of cold or room temperature soft foods; based on stability studies, only applesauce, carrots, rice, or ice cream should be used. The packet should not be opened until ready to use. After opening the packet, the full dose (with or without mixing with baby formula, breast milk, or food) must be administered within 15 minutes. If mixed with baby formula, breast milk, or food, Montelukast oral granules must not be stored for future use. Discard any unused portion. Montelukast oral granules are not intended to be dissolved in any liquid other than baby formula or breast milk for administration. However, liquids may be taken subsequent to administration. Montelukast oral granules can be administered without regard to the time of meals. Return to top