Amitriptyline

Synonyms / Brand Names: Amitriptyline Hydrochloride, Amitriptyline HCL, Amitriprolidine, Amitriptylin, Amitryptiline, Amitryptyline, Amytriptiline, Adepress, Adepril, Amitid, Amitril, Damilan, Damilen, dAmitriptyline, Elanil, Elavil, Endep, Flavyl, Hexathane, Horizon, Lantron, Laroxil, Laroxyl, Lentizol, Proheptadiene, Redomex, Saroten, Sarotex, Seroten, Sylvemid, Triptanol, Triptilin, Triptisol, Tryptanol, Tryptizol

Dosing and Administration
For outpatients, 75 mg of Amitriptyline HCl a day in divided doses is usually satisfactory. If necessary, this may be increased to a total of 150 mg per day. Increases are made preferably in the late afternoon and/or bedtime doses. A sedative effect may be apparent before the antidepressant effect is noted, but an adequate therapeutic effect may take as long as 30 days to develop. An alternate method of initiating therapy in outpatients is to begin with 50 to 100 mg Amitriptyline HCl at bedtime. This may be increased by 25 or 50 mg as necessary in the bedtime dose to a total of 150 mg per day. Hospitalized patients may require 100 mg a day initially. This can be increased gradually to 200 mg a day if necessary. A small number of hospitalized patients may need as much as 300 mg a day.

FDA Package Insert Resources Indications, Contraindications, Side Effects, Drug Interactions, etc. Calculate Creatine Clearance On line calculator of your patients Cr Cl by a variety of formulas. Convert pounds to Kilograms On line calculator of your patients weight in pounds to Kg for dosing estimates. Publication Resources Recent articles, WikiDoc State of the Art Review, Textbook Information Trial Resources Ongoing Trials, Trial Results Guidelines & Evidence Based Medicine Resources US National Guidelines, Cochrane Collaboration, etc. Media Resources Slides, Video, Images, MP3, Podcasts, etc. Patient Resources Discussion Groups, Handouts, Blogs, News, etc. International Resources en Español

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