Alanopine dehydrogenase

In enzymology, an alanopine dehydrogenase is an enzyme that catalyzes the chemical reaction


 * 2,2'-iminodipropanoate + NAD+ + H2O $$\rightleftharpoons$$ L-alanine + pyruvate + NADH + H+

The 3 substrates of this enzyme are 2,2'-iminodipropanoate, NAD+, and H2O, whereas its 4 products are L-alanine, pyruvate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming). Other names in common use include ALPDH, alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase, meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase, alanopine: NAD+ oxidoreductase, ADH, and alanopine:NAD+ oxidoreductase.