Aspartate-tRNAAsn ligase

In enzymology, an aspartate-tRNAAsn ligase is an enzyme that catalyzes the chemical reaction


 * ATP + L-aspartate + tRNAAsx $$\rightleftharpoons$$ AMP + diphosphate + aspartyl-tRNAAsx

The 3 substrates of this enzyme are ATP, L-aspartate, and tRNAAsx, whereas its 3 products are AMP, diphosphate, and aspartyl-tRNAAsx.

This enzyme belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-aspartate:tRNAAsx ligase (AMP-forming). This enzyme is also called nondiscriminating aspartyl-tRNA synthetase. This enzyme participates in alanine and aspartate metabolism.