Phosphoserine phosphatase

In enzymology, a phosphoserine phosphatase is an enzyme that catalyzes the chemical reaction


 * O-phospho-L(or D)-serine + H2O $$\rightleftharpoons$$ L(or D)-serine + phosphate

The 3 substrates of this enzyme are O-phospho-L-serine, O-phospho-D-serine, and H2O, whereas its 3 products are L-serine, D-serine, and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is O-phosphoserine phosphohydrolase. This enzyme participates in glycine, serine and threonine metabolism.

Structural studies
As of late 2007, 12 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , and.