The Living Guidelines: UA/NSTEMI Recommendations for Inhibition of the Renin-Angiotensin-Aldosterone System Suggest Revisions to the CLASS IIa Guidelines

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Class IIa Guidelines

 * 1) Angiotensin-converting enzyme inhibitors are reasonable for patients recovering from UA / NSTEMI in the absence of LV dysfunction, hypertension, or diabetes mellitus unless contraindicated. (Level of Evidence: A)
 * 2) Angiotensin-converting enzyme inhibitors are reasonable for patients with HF and LVEF >40%. (Level of Evidence: A)
 * 3) In UA / NSTEMI patients who do not tolerate ACE inhibitors, an angiotensin receptor blocker can be useful as an alternative to ACE inhibitors in long term management provided there are either clinical or radiological signs of HF and LVEF <40%. (Level of Evidence: B)