Low density lipoprotein receptor-related protein 8

Low density lipoprotein receptor-related protein 8, or LRP8 (also Apolipoprotein E Receptor 2; ApoER2) is a member of the LDL receptor family that plays a role in endocytosis and signal transduction. Together with VLDLR it is able to bind reelin, leading to the phosphorylation of DAB1, which binds on its cytosolic tail.