Risperidone drug interactions

List of drug interactions
Overview Carbamazepine/other enzyme inducers Fluoxetine/paroxetine Lithium Valproate Digoxin Drugs that inhibit CYP 2D6/other CYP isozymes Drugs metabolized by CYP 2D6

Overview
The interactions of Risperidone and other drugs have not been systematically evaluated. Given the primary CNS effects of risperidone, caution should be used when Risperidone is taken in combination with other centrally acting drugs and alcohol. Because of its potential for inducing hypotension, Risperidonemay enhance the hypotensive effects of other therapeutic agents with this potential. Risperidone may antagonize the effects of levodopa and dopamine agonists. Amitriptyline did not affect the pharmacokinetics of risperidone or the active moiety. Cimetidine and ranitidine increased the bioavailability of risperidone by 64% and 26%, respectively. However, cimetidine did not affect the AUC of the active moiety, whereas ranitidine increased the AUC of the active moiety by 20%. Chronic administration of clozapine with risperidone may decrease the clearance of risperidone. Topiramate modestly reduced the bioavailability of risperidone, but not that of active antipsychotic fraction. Therefore this interaction is unlikely to be of clinical significance. Return to top

Carbamazepine/other enzyme inducers
In a drug interaction study in schizophrenic patients, 11 subjects received risperidone titrated to 6 mg/day for 3 weeks, followed by concurrent administration of carbamazepine for an additional 3 weeks. During co-administration, the plasma concentrations of risperidone and its pharmacologically active metabolite, 9-hydroxyrisperidone, were decreased by about 50%. Plasma concentrations of carbamazepine did not appear to be affected. The dose of risperidone may need to be titrated accordingly for patients receiving carbamazepine, particularly during initiation or discontinuation of carbamazepine therapy. Co-administration of other known enzyme inducers (e.g., phenytoin, rifampin, and phenobarbital) with risperidone may cause similar decreases in the combined plasma concentrations of risperidone and 9-hydroxyrisperidone, which could lead to decreased efficacy of risperidone treatment. Return to top

Fluoxetine/paroxetine
Fluoxetine (20 mg QD) and paroxetine (20 mg QD) have been shown to increase the plasma concentration of risperidone 2.5–2.8 fold and 3–9 fold respectively. Fluoxetine did not affect the plasma concentration of 9-hydroxyrisperidone. Paroxetine lowered the concentration of 9-hydroxyrisperidone by about 10%. When either concomitant fluoxetine or paroxetine is initiated or discontinued, the physician should re-evaluate the dosing of Risperdal®. The effects of discontinuation of concomitant fluoxetine or paroxetine therapy on the pharmacokinetics of risperidone and 9-hydroxyrisperidone have not been studied. Return to top

Lithium
Repeated oral doses of risperidone (3 mg BID) did not affect the exposure (AUC) or peak plasma concentrations (Cmax) of lithium (n=13). Return to top

Valproate
Repeated oral doses of risperidone (4 mg QD) did not affect the pre-dose or average plasma concentrations and exposure (AUC) of valproate (1000 mg/day in three divided doses) compared to placebo (n=21). However, there was a 20% increase in valproate peak plasma concentration (Cmax) after concomitant administration of risperidone. Return to top

Digoxin
Risperidone (0.25 mg BID) did not show a clinically relevant effect on the pharmacokinetics of digoxin. Return to top

Drugs that inhibit CYP 2D6/other CYP isozymes
Risperidone is metabolized to 9-hydroxyrisperidone by CYP 2D6, an enzyme that is polymorphic in the population and that can be inhibited by a variety of psychotropic and other drugs. Drug interactions that reduce the metabolism of risperidone to 9-hydroxyrisperidone would increase the plasma concentrations of risperidone and lower the concentrations of 9-hydroxyrisperidone. Analysis of clinical studies involving a modest number of poor metabolizers (n70) does not suggest that poor and extensive metabolizers have different rates of adverse effects. No comparison of effectiveness in the two groups has been made. In vitro studies showed that drugs metabolized by other CYP isozymes, including 1A1, 1A2, 2C9, 2C19, and 3A4, are only weak inhibitors of risperidone metabolism. There were no significant interactions between risperidone and erythromycin.Return to top

Drugs metabolized by CYP 2D6
In vitro studies indicate that risperidone is a relatively weak inhibitor of CYP 2D6. Therefore, Risperdal® is not expected to substantially inhibit the clearance of drugs that are metabolized by this enzymatic pathway. In drug interaction studies, risperidone did not significantly affect the pharmacokinetics of donepezil and galantamine, which are metabolized by CYP 2D6. Return to top

Major Interactions
amiodarone, Anzemet, arsenic trioxide, Avelox, Avelox I.V., bepridil, Betapace, Betapace AF, Betapace AF(obsolete), Budeprion SR, Budeprion XL, buPROPion, buPROPion 24 hour extended release, buPROPion extended release, Cardioquin, Chem Mart Tramadol, cisapride, Clopine, clozapine, Clozapine Synthon, Clozaril, Cordarone, Cordarone I.V., Corvert, Darvon, Darvon-N, Denzapine, Diskets, disopyramide, disopyramide extended release, dofetilide, dolasetron, Dolophine, Dromadol SR, Dromadol XL, droperidol, FazaClo, gatifloxacin, GenRx Tramadol, Geodon, GHB, grepafloxacin, Haldol, Haldol Decanoate, Halfan, halofantrine, haloperidol, haloperidol decanoate, ibutilide, Inapsine, iohexol, iopamidol, Iopamidol-370, Isovue-128, Isovue-200, Isovue-250, Isovue-300, Isovue-370, Isovue-M-200, Isovue-M-300, Larapam SR, levomethadyl acetate, Mellaril, Mellaril-S, mesoridazine, methadone, Methadose, metrizamide, moxifloxacin, Myelo-Kit, nilotinib, Norpace, Norpace CR, Omnipaque 140, Omnipaque 180, Omnipaque 180 Redi-Unit, Omnipaque 210, Omnipaque 240, Omnipaque 240 Redi-Unit, Omnipaque 300, Omnipaque 350, Omnipaque Flexipak, Orap, Orlaam, Pacerone, pimozide, PP-Cap, procainamide, procainamide 12 hour extended release, procainamide extended release, Procan SR, Procanbid, Pronestyl, Pronestyl-SR, propoxyphene, propoxyphene hydrochloride, propoxyphene napsylate, Propulsid, Quin-G, Quin-Release, Quinaglute Dura-Tabs, Quinidex Extentabs, quinidine, quinidine extended release, Quinora, Ranexa, ranolazine, Raxar, Serentil, sodium biphosphate, sodium oxybate, Sorine, sotalol, Sotalol Hydrochloride AF, Sotalol Hydrochloride AF(obsolete), sparfloxacin, Tasigna, Tequin, Tequin Teqpaq, Terry White Chemists Tramadol, thioridazine, Tikosyn, Topamax, Topamax Sprinkle, topiramate, traMADOL, traMADOL extended release, Tramahexal, Tramahexal SR, Tramake, Tramake Insts, Tramal, Tramal SR, Tramedo, Trisenox, Ultram, Ultram ER, Vascor, Wellbutrin, Wellbutrin SR, Wellbutrin XL, Xyrem, Zagam, Zagam Respipac, Zamadol, Zamadol 24hr, Zamadol Melt, Zamadol SR, Zaponex, ziprasidone, Zonegran, zonisamide, Zyban, Zyban Advantage Pack, Zydol, Zydol SR, Zydol XL

Moderate Interactions
40 Winks, A-Hydrocort, A-Spas S/L, abarelix, Abelcet, Abilify, Abilify Discmelt, acarbose, Accuneb, Accupril, acebutolol, Aceon, acetaZOLAMIDE, acetaZOLAMIDE extended release, acetoHEXAMIDE, acetylcarbromal, acetylcholine ophthalmic, acrivastine, Actiq, Adalat, Adalat CC, Adapin, Adeno-jec, Adenocard, Adenoscan, adenosine, adenosine monophosphate, adenosine triphosphate, Adgan, Adrenalin, Adriamycin, Adriamycin RDF, Adsorbocarpine, Afeditab CR, AHist, Airet, Akarpine, Akineton HCl, albuterol, albuterol extended release, alcohol, alcohol, ethyl, Aldactone, Aldomet, Aler-Dryl, Aler-Tab, Alfenta, alfentanil, alfuzosin, alfuzosin extended release, All Day Allergy, Aller-Chlor, Allergia-C, Allerhist-1, Allermax, Alophen, Aloxi, Alphagan, Alphagan P, alprazolam, alprazolam extended release, Altace, Altaryl, Alupent, amantadine, Amaryl, Ambien, Ambien CR, amiloride, amitriptyline, amlodipine, amobarbital, amoxapine, Amphocin, amphotericin B, amphotericin B lipid complex, Amrix, amyl nitrite, Amytal Sodium, Ana-Guard, Anafranil, Anaspaz, Anergan 50, Antiflex, Antilirium, Antinaus 50, Antivert, Apidra, Apidra OptiClik Cartridge, APO-Go, APO-Go Pen, Apokyn, apomorphine, apraclonidine ophthalmic, Apresoline, Aquachloral Supprettes, Aquacot, Aquatensen, Aquazide H, Aralen Hydrochloride, Aralen Phosphate, Arfonad, arformoterol, Aricept, Aricept ODT, aripiprazole, Artane, Asendin, Astelin, astemizole, Asthmahaler, Asthmanefrin, Astramorph PF, Atacand, Atarax, atenolol, Ativan, Atreza, AtroPen, atropine, Avapro, Aventyl HCl, Avinza, azatadine, azelastine nasal, azithromycin, Azithromycin 3 Day Dose Pack, Azithromycin 5 Day Dose Pack, azithromycin extended release, B-Vex, baclofen, Banaril, Banflex, Banophen, Beldin, Belix, belladonna, Belladonna Tincture, Ben-Tann, Benadryl, Benadryl Allergy, Benadryl Child Dye Free, Benadryl Childrens Allergy Fastmelt, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Benahist-10, Benahist-50, benazepril, bendroflumethiazide, Benicar, Benoject-50, Bentyl, Benzacot, benzthiazide, benztropine, betaxolol, Biaxin, Biaxin XL, Biaxin XL-Pak, Bidhist, biperiden, Bisa-Plex, Bisac-Evac, bisacodyl, Bisco-Lax, Bisolax, bisoprolol, bitolterol, Black Draught, Blocadren, Bonine, Brethaire, Brethine, Brevibloc, Bricanyl, brimonidine ophthalmic, Bromaphen, bromocriptine, bromodiphenhydramine, brompheniramine, brompheniramine extended release, Bronchial Mist with Pump, Bronitin, Bronkaid Mist, Bronkometer, Brovana, BroveX, BroveX CT, bumetanide, Bumex, Buprenex, buprenorphine, Busodium, BuSpar, BuSpar Dividose, busPIRone, butabarbital, butalbital, Butisol Sodium, butorphanol, butorphanol nasal, Bydramine, Bystolic, C.P.M., cabergoline, Calan, Calan SR, Calm-Aid, candesartan, Cantil, Capastat Sulfate, Capoten, capreomycin, captopril, carbachol ophthalmic, Carbacot, carbamazepine, carbamazepine extended release, Carbatrol, carbetapentane, carbinoxamine, carbinoxamine extended release, Carbinoxamine PD, Carboptic, Carboxine, Cardene, Cardene IV, Cardene SR, Cardizem, Cardizem CD, Cardizem LA, Cardizem Monovial, Cardizem SR, Cardura, Cardura XL, Carduran, carisoprodol, Carozide, carteolol, Carters Little Pills, Cartia XT, Cartrol, carvedilol, carvedilol extended release, Cascor, Catapres, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3, Celebrex, celecoxib, Celexa, Celontin, Cerebyx, Cerubidine, Cesamet, cetirizine, Chem Mart Tamoxifen, Chlo-Amine, Chlor-Al Rel, Chlor-Mal, Chlor-Phen, Chlor-Phenit, Chlor-Trimeton, Chlor-Trimeton Allergy SR, chloral hydrate, chlordiazepoxide, chlormezanone, chloroquine, chloroquine hydrochloride, chloroquine phosphate, chlorothiazide, Chlorphen, chlorphenesin, chlorpheniramine, Chlorpheniramine (Allergy), chlorpheniramine 24 hour extended release, chlorpheniramine extended release, chlorproMAZINE, chlorproMAZINE extended release, chlorproPAMIDE, ChlorTan, chlorthalidone, chlorzoxazone, cinacalcet, Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR, ciprofloxacin, ciprofloxacin extended release, cisplatin, citalopram, clarithromycin, clarithromycin extended release, clemastine, clidinium, clomiPRAMINE, clonazepam, clonidine, clonidine topical, clorazepate, clorazepate extended release, codeine, codeine phosphate, codeine sulfate, Codimal A, Cogentin, Cognex, Colax, Colocort, Compazine, Compazine Spansule, Compoz Nighttime Sleep Aid, Compro, Comtan, Contac 12 Hour Allergy, Cophene B, Cordron NR, Coreg, Coreg CR, Corgard, Corlopam, Correctol, Cortef, Cortenema, Cortifoam, cortisone, Cortone Acetate, Cortrosyn, cosyntropin, Covera-HS, Cozaar, cyclandelate, cyclizine, cyclobenzaprine, cyclobenzaprine extended release, Cyclospasmol, Cymbalta, cyproheptadine, Cystospaz, Cystospaz-M, D-Vert, Dailyhist-1, Dalgan, Dalmane, Dantrium, Dantrium Intravenous, dantrolene, darifenacin, dasatinib, DAUNOrubicin, DAUNOrubicin liposomal, Daunoxome, Dazidox, Definity, Dehydrated Alcohol, Demadex, Demadex I.V., demecarium bromide ophthalmic, Demerol HCl, Depacon, Depakene, Depakote, Depakote ER, Depakote Sprinkles, DepoDur, Deponit, deserpidine, desipramine, desvenlafaxine, Desyrel, Desyrel Dividose, Detrol, Detrol LA, dexbrompheniramine, dexchlorpheniramine, dexchlorpheniramine extended release, dexmedetomidine, dezocine, Di-Phen, DiaBeta, Diabinese, Diamode, Diamox, Diamox Sequels, Diaqua, Diaqua-2, Diar-Aid, Diastat, Diastat AcuDial, Diastat Pediatric, diazepam, diazoxide, Dibenzyline, Dicyclocot, dicyclomine, Digibind, DigiFab, digoxin immune FAB, dihydrocodeine, Dilacor XR, Dilantin, Dilantin Infatabs, Dilantin Kapseals, Dilantin-125, Dilatrate-SR, Dilaudid, Dilaudid-5, Dilaudid-HP, Diltia XT, diltiazem, diltiazem 24 hour extended release, diltiazem extended release, Diltiazem Hydrochloride CD, Diltiazem Hydrochloride SR, Diltiazem Hydrochloride XR, Diltiazem Hydrochloride XT, dimenhyDRINATE, Dimetane, Dimetane Extentab, Dimetapp Allergy, Dimetapp Allergy Liquigel, Diovan, Diphedryl, Diphen, Diphen AF, Diphen Cough, Diphenadryl, Diphendryl, Diphenhist, diphenhydrAMINE, diphenhydrAMINE citrate, diphenhydrAMINE tannate, Diphenmax, Diphenydramine Quick Melt, Diphenyl, Diphenylin, Diprivan, Ditropan, Ditropan XL, Diucardin, Diurese, Diuril, Diuril Sodium, divalproex sodium, divalproex sodium extended release, Dizac, DMH, Doloral, Doloral Sirop, donepezil, Donnamar, DOPamine, Dopar, Doral, Dosaflex, Dostinex, Doxadura, doxazosin, doxazosin extended release, doxepin, doxepin topical, Doxidan Tablet, Doxil, DOXOrubicin, DOXOrubicin liposomal, doxylamine, DPH, Dr Caldwell Laxative, Dramamine, Dramamine II, Dramoject, Driminate, Driminate II, dronabinol, Dulcogen, Dulcolax Laxative, duloxetine, Duraclon, Duragesic, Duragesic-100, Duragesic-12, Duragesic-25, Duragesic-50, Duragesic-75, Duramorph PF, Dymelor, Dymenate, Dynacirc, Dynacirc CR, Dyrenium, Dytan, Dytuss, E-Mycin, E.E.S. Granules, E.E.S.-200, E.E.S.-400, E.E.S.-400 Filmtab, echothiophate iodide ophthalmic, Ed Chlor-Tan, Ed ChlorPed, Edecrin, Edecrin Sodium, Effexor, Effexor XR, Efidac-24 Chlorpheniramine, Elavil, Ellence, Emblon, ENA 713, Enablex, enalapril, enalaprilat, Endep, Endocodone, Enduron, entacapone, Epi EZ Pen, epinephrine, EpiPen 2-Pak, EpiPen Auto-Injector, EpiPen JR 2-Pak, EpiPen JR Auto-Injector, epirubicin, Epitol, eplerenone, eprosartan, Equanil, Equetro, Ery-Tab, Eryc, EryPed, EryPed 200, EryPed 400, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, Erythrocot, erythromycin, erythromycin base, erythromycin estolate, erythromycin ethylsuccinate, erythromycin lactobionate, erythromycin stearate, escitalopram, Eserine Sulfate Ophthalmic, Esidrix, Eskalith, Eskalith-CR, esmolol, estazolam, eszopiclone, ETH-Oxydose, ethacrynic acid, ethanol, Ethaquin, Ethatab, ethaverine, Ethavex-100, ethosuximide, ethotoin, Ethyl Alcohol, Evac-U-Gen, Ex-Lax Chocolated, Ex-Lax Gentle Nature, Ex-Lax Maximum Relief Formula, Ex-Lax Regular Strength Pills, Ex-lax Ultra, Exelon, Exna, EXUBERA, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, Eze D.S., Ezide, Factive, Feen-A-Mint, felbamate, Felbatol, felodipine, felodipine extended release, fenoldopam, fentanyl, fentanyl topical, Fentora, Fexmid, FK506, flavoxate, flecainide, Fleet Bisacodyl, Fletchers Castoria, Flexeril, Flexoject, Flexon, Florinef Acetate, Floxin, Floxin I.V., fludrocortisone, Fluothane, fluoxetine, fluoxetine extended release, fluphenazine, fluphenazine decanoate, fluphenazine enanthate, fluphenazine hydrochloride, flurazepam, fluvoxamine, fluvoxamine extended release, Foradil Aerolizer, formoterol, Fortamet, foscarnet, Foscavir, fosinopril, fosphenytoin, Fungizone, Fungizone For Tissue Culture, furosemide, gabapentin, Gabarone, Gabitril, galantamine, galantamine extended release, gemifloxacin, Gen Lax, Genahist, Genox, GenRx Tamoxifen, Gentlax, Gentlax Tablet, Gentle Laxative, Gleevec, glimepiride, glipiZIDE, glipiZIDE extended release, GlipiZIDE XL, Glucophage, Glucophage XR, Glucotrol, Glucotrol XL, Glumetza, glyBURIDE, glyBURIDE micronized, glycopyrrolate, Glynase PresTab, Glyset, guanabenz, guanadrel, guanethidine, guanfacine, halazepam, Halcion, halothane, Harmonyl, HCTZ, Hismanal, Histaject, Histex CT, Histex I/E, Histex PD, Histex Pd 12, homatropine, Humalog, Humalog Cartridge, Humalog KwikPen, Humalog Pen, Humorsol Ocumeter, Humulin L, Humulin N, Humulin N Pen, Humulin R, Humulin R (Concentrated), Humulin U, hydrALAZINE, Hydramine, Hydramine Compound, Hydramine Cough Syrup, Hydrate, Hydro Par, hydrochlorothiazide, hydrocodone, hydrocortisone, hydrocortisone acetate, hydrocortisone cypionate, hydrocortisone hemisuccinate, hydrocortisone sodium phosphate, Hydrocortisone Sodium Succinate, Hydrocortone, Hydrocortone Phosphate, HydroDIURIL, hydroflumethiazide, Hydromorph Contin, hydromorphone, hydromorphone extended release, Hydrostat IR, hydrOXYzine, hydrOXYzine hydrochloride, hydrOXYzine pamoate, Hygroton, Hylorel, hyoscyamine, hyoscyamine extended release, Hyosol, Hyospaz, Hyosyne, hypericum perforatum, Hyperstat, Hyrexin, Hytrin, Hyzine, IB-Stat, Idamycin PFS, idarubicin, Iletin II Lente Pork, Iletin II NPH Pork, Iletin II Regular Pork, Iletin Lente, Iletin NPH, Iletin Regular, Ilosone, Ilotycin Gluceptate, imatinib, Imdur, imipramine, imipramine pamoate, Imodium, Imodium A-D, Imodium A-D EZ Chews, Imodium A-D New Formula, Imotil, indapamide, Inderal, Inderal LA, Infumorph, Innerclean, InnoPran XL, Inspra, insulin, insulin analog, insulin aspart, insulin aspart protamine, insulin detemir, insulin glargine, insulin glulisine, insulin inhalation, rapid acting, insulin isophane, Insulin Lente Pork, insulin lispro, insulin lispro protamine, Insulin Purified NPH Pork, Insulin Purified Regular Pork, insulin regular, insulin zinc, insulin zinc extended, insulin, lente, insulin, NPH, insulin, ultralente, Intropin, Invega, Inversine, Ionsys, Iopidine, irbesartan, ISDN, Ismelin, ISMO, Ismotic PB, isocarboxazid, Isochron, isoetharine, isoflurophate ophthalmic, isoproterenol, Isoptin, Isoptin I.V., Isoptin SR, Isopto Carbachol, Isopto Carpine, Isordil, Isordil Tembids, Isordil Titradose, isosorbide, isosorbide dinitrate, isosorbide dinitrate extended release, isosorbide mononitrate, isosorbide mononitrate extended release, Isovex, isoxsuprine, isradipine, isradipine extended release, Isuprel HCl, Isuprel Mistometer, J-Tan, J-Tan PD, Januvia, Kadian, Kao-Paverin, Kaopectate Caplet, Kayexalate, Kemadrin, Keppra, Kerlone, Ketalar, ketamine, Ketek, Ketek Pak, Kionex, Klonopin, Klonopin Wafer, L-hyoscyamine, labetalol, Lamictal, Lamictal Blue, Lamictal CD, Lamictal Green, Lamictal Orange, Lamisil, lamotrigine, Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen, lapatinib, Largon, Lariam, Larodopa, Lasix, Laxative Gentle Suppositories, Lente insulin, levalbuterol, Levaquin, Levaquin Leva-Pak, Levatol, Levbid, Levemir, Levemir FlexPen, Levemir InnoLet, Levemir PenFill, levetiracetam, Levitra, Levo-Dromoran, levocetirizine, levodopa, levofloxacin, levonordefrin, Levoprome, levorphanol, LEVRIX, Levsin, Levsin SL, Levsinex SR, Lexapro, Librium, lindane topical, Lioresal, Lioresal Intrathecal, lisinopril, lithium, lithium carbonate, lithium carbonate extended release, lithium citrate, Lithobid, Lithonate, Lithotabs, Lo-Aqua, Lodrane 12 Hour, Lodrane 24, Lodrane XR, Loniten, loperamide, Lopressor, Loqua, lorazepam, Lorelco, losartan, Lotensin, loxapine, Loxitane, Loxitane C, Loxitane IM, Lozol, Ludiomil, Luminal, Lunesta, Luvox, Luvox CR, Lyrica, M-Eslon, M-Oxy, M. O. S., Maalox Anti-Diarrheal, Magic Bullet, Maldemar, Maolate, maprotiline, Marezine, Marinol, Marplan, Mavik, Maxair, Maxair Autohaler, MB-TAB, Mebaral, mecamylamine, Meclicot, meclizine, Medihaler-Epi, Medihaler-Iso, Medivert, mefloquine, memantine, Meni-D, mepenzolate, meperidine, mephenytoin, mephobarbital, meprobamate, Meridia, Mesantoin, Metahydrin, Metaprel, metaproterenol, metaxalone, metformin, metformin extended release, methdilazine, methocarbamol, methotrimeprazine, methscopolamine, methsuximide, methyclothiazide, methyldopa, metoclopramide, metolazone, metoprolol, metoprolol extended release, metoprolol succinate, Metoprolol Succinate ER, metoprolol tartrate, mibefradil, Micardis, Micronase, Micronefrin, Microzide, Midamor, midazolam, miglitol, Milontin, Miltown, Minipress, Minitran, minoxidil, Mio-Rel, Miochol, Miochol-E, Miochol-E System Pak, Miochol-E/Steri-Tags, Miostat, Mirapex, mirtazapine, Mitran, Moban, Modane, moexipril, molindone, Monoket, Monopril, morphine, morphine 24 hour extended release, morphine extended release, Morphine IR, morphine liposomal, Morphine LP Epidural, morphine preservative-free, Morphine Rapi-Ject, Morphitec, MS, MS Contin, MS/S, MSIR, MY-E, My-O-Den, Mykrox, Myolin, Mysoline, nabilone, nadolol, nalbuphine, Namenda, Naqua, Nardil, Nasahist B, nateglinide, Naturetin-10, Naturetin-5, Navane, ND-Stat, nebivolol, Nebupent, nefazodone, Nembutal, Nembutal Sodium, Nephron, Nervine, Neupro, Neurontin, niCARdipine, niCARdipine extended release, Nifediac CC, Nifedical XL, NIFEdipine, NIFEdipine extended release, Nightime Sleepaid, nimodipine, Nimotop, Niravam, nisoldipine, Nitrek, Nitro TD Patch-A, Nitro-Bid, Nitro-Bid IV, Nitro-Dur, Nitro-Par, Nitro-Time, Nitrocot, Nitrodisc, Nitrogard, nitroglycerin, Nitroglyn E-R, Nitrol, Nitrol Appli-Kit, Nitrolingual, Nitrong, Nitropress, nitroprusside, Nitroquick, Nitrostat, Nolahist, Nolvadex, Nolvadex D, Norflex, Norflex Injectable, norfloxacin, Normodyne, Noroxin, Norpramin, nortriptyline, Norvasc, Norvir, Norvir Soft Gelatin, Novolin L, Novolin N, Novolin N Innolet, Novolin N PenFill, Novolin R, Novolin R Innolet, Novolin R PenFill, NovoLog, NovoLog FlexPen, NovoLog PenFill, NPH insulin, NTG, Nu-Med, Nubain, Nulev, Numorphan HCl, Nytol Caplet, Nytol Maximum Strength, Ocu-Carpine, Ocusert, ofloxacin, olanzapine, olmesartan, olopatadine nasal, OMS, ondansetron, Opana, Opana ER, opium, Opium Deodorized, Optimine, Optison, Oramorph SR, Oretic, Orfro, Orinase, Ormazine, orphenadrine, orphenadrine extended release, Orphenate, oxazepam, oxcarbazepine, oxybutynin, oxybutynin extended release, oxycodone, oxycodone extended release, OxyContin, Oxyfast, OxyIR, oxymorphone, oxymorphone extended release, Oxytrol, P-Tann, P-Tex, Palgic, paliperidone, Palladone, Palladone SR, palonosetron, Pamelor, Pamine, Pamine Forte, Papacon, papaverine, papaverine extended release, Para-Time S. R., Paradione, Paraflex, Parafon Forte DSC, Paral, paraldehyde, paramethadione, Pardryl, Paregoric, Parlodel, Parnate, paroxetine, paroxetine extended release, paroxetine mesylate, Patanase, Pavabid Plateau, Pavacot, Pavagen, Paxarel, Paxil, Paxil CR, PBZ, PBZ-SR, PCE Dispertab, Pedia-Lax, PediaTan, Pediatex, Pediatex 12, Pediox, Pediox-S, Peganone, penbutolol, Pentam 300, pentamidine, Pentazine, pentazocine, pentobarbital, Pepto Diarrhea Control, Percolone, Perdiem Overnight, perflutren, Perforomist, pergolide, Periactin, perindopril, Permax, Permitil, perphenazine, Pexeva, Pharmorubicin PFS, Pharmorubicin RDF, phenacemide, Phenadoz, Phenazine 50, phenelzine, Phenergan, Phenergan Fortis, phenindamine, pheniramine, phenobarbital, Phenoject-50, phenoxybenzamine, phensuximide, phentolamine, Phenurone, phenyltoloxamine, Phenytek, phenytoin, phenytoin extended release, Phenytoin Sodium, Prompt, Phospholine Iodide, physostigmine, physostigmine ophthalmic, Pilagan with C Cap, Pilocar, pilocarpine nitrate ophthalmic, pilocarpine ophthalmic, Pilopine-HS, Piloptic-1, Piloptic-1/2, Piloptic-2, Piloptic-3, Piloptic-4, Piloptic-6, Pilostat, pindolol, pirbuterol, Pitressin, Platinol-AQ, Plenaxis, Plendil, Polaramine, Polaramine Repetabs, polythiazide, Posicor, pramipexole, Prandin, prazosin, Precedex, Precose, pregabalin, Prialt, Primatene Mist Inhaler, Primatene Mist Suspension, primidone, Prinivil, Pristiq, Pro-Banthine, Pro-Med, ProAir HFA, probucol, Procardia, Procardia XL, prochlorperazine, prochlorperazine extended release, Procot, procyclidine, Proglycem, Prograf, Prolixin, Prolixin Decanoate, Prolixin Enanthate, Promacot, promazine, promethazine, Promethegan, Prop-A-Tane, propafenone, propafenone extended release, propantheline, propiomazine, propofol, propranolol, propranolol extended release, Proquin XR, Prorex, Prosom, protamine zinc insulin, protriptyline, Proventil, Proventil HFA, Proventil Repetabs, Prozac, Prozac Weekly, Prudoxin, pyrilamine, pyrilamine extended release, Pyrlex, Q-Dryl, Q-Dryl A/F, QDALL AR, QM-260, Qualaquin, Quarzan, quazepam, Quenalin, quetiapine, quetiapine extended release, quinapril, quinine, racepinephrine, ramipril, Rapiflux, Rauwolfemms, Rauwolfia 1X, rauwolfia serpentina, Razadyne, Razadyne ER, Reglan, regular insulin, Regurin, Relaxazone, ReliOn/Novolin N, ReliOn/Novolin R, Remeron, Remeron SolTab, remifentanil, Reminyl, Remular, Remular-S, Renese, repaglinide, Repreve, Requip, ReQuip Follow on Pack, Requip Starter Kit, ReQuip Starter Pack, Rescudose, reserpine, Respirol, Restoril, Rezine, Ridramin, Riomet, ritodrine, ritonavir, rivastigmine, RMS, Robaxin, Robaxin-750, Robimycin, Robinul, Robinul Forte, Rohist, ropinirole, rotigotine, Roxanol, Roxanol 100, Roxanol-T, Roxicodone, Roxicodone Intensol, Ru-Vert-M, Rythmol, Rythmol SR, S2 Inhalant, Sal-Tropine, salmeterol, Saluron, Sanctura, Sanctura XR, Sarafem, Scopace, scopolamine, scopolamine topical, Scot-Tussin Allergy Relief Formula, secobarbital, Seconal Sodium, Sectral, Selfemra, Senexon, Senna, Senna Concentrate, Senna Lax, Senna Smooth, Senna-gen, Sennalax, Senokot, Senokot Child, Senokot Extra, SenokotXTRA, Senolax, SenoSol, SenoSol-X, Sensipar, Serax, Serevent, Serevent Diskus, Seroquel, Seroquel XR, sertraline, Serzone, sibutramine, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Siltane, Simply Sleep, Sinequan, sitagliptin, Skelaxin, Skelex, Sleep Tab II, Sleep Tabs, Sleep-ettes, Sleep-Eze-3, Sleepinal, sodium nitroprusside, sodium polystyrene sulfonate, sodium valproate, Solfoton, solifenacin, solotuss, Soltamox, Solu-Cortef, Soma, Sominex, Sominex Maximum Strength Caplet, Somnicaps, Somnote, Sonata, Sorbitrate, Sparine, Spasdel, spironolactone, Sprycel, St. John's wort, Stadol, Stadol NS, Starlix, Statex, Stelazine, Strifon Fort, Sublimaze, Subutex, Sufenta, sufentanil, Sular, Surmontil, Sus-Phrine Injection, Symax Duotab, Symax FasTab, Symax SL, Symax SR, Symmetrel, Tacaryl, tacrine, tacrolimus, Talwin Lactate, Tambocor, Tamofen, Tamofen(obsolete), Tamone, Tamosin, Tamoxen, tamoxifen, Tamoxifen Hexal, Tanacof-XR, TanaHist-PD, Tasmar, Tavist, Tavist Allergy, Tavist-1, Taztia XT, Tegretol, Tegretol XR, telithromycin, telmisartan, Temaril, temazepam, Tenex, Tenormin, terazosin, terbinafine, terbutaline, terfenadine, Terry White Chemists Tamoxifen, tetrahydroaminocrideine, Teveten, thalidomide, Thalitone, Thalomid, Theraflu Thin Strips Multi Symptom, thiethylperazine, thiothixene, Thorazine, tiagabine, Tiazac, Ticon, Tigan, timolol, tizanidine, Tofranil, Tofranil-PM, Tol-Tab, TOLAZamide, tolazoline, TOLBUTamide, tolcapone, Tolinase, tolterodine, tolterodine extended release, Toprol-XL, Torecan, Tornalate, torsemide, Total Allergy, Trancopal, Trandate, trandolapril, Transderm-Scop, Tranxene SD, Tranxene T-Tab, tranylcypromine, traZODONE, Triaminic Allergy, Triaminic Thin Strips Cough & Runny Nose, triamterene, triazolam, trichlormethiazide, Tridil, Tridione, trifluoperazine, triflupromazine, Trihexane, trihexyphenidyl, Trilafon, Trileptal, trimeprazine, trimethadione, trimethaphan camsylate, trimethobenzamide, trimipramine, tripelennamine, Tripohist, triprolidine, triprolidine extended release, Triptone, trospium, trospium extended release, Trux-adryl, Tusstat, Twilite, Twinject Auto-Injector, Twinject Auto-Injector Two Pack, Tykerb, Ultiva, Ultralente insulin, Uni-Cenna, Uni-Tann, Unisom, Unisom Sleepgels Maximum Strength, Univasc, Uprima, Urispas, Urotrol, Uroxatral, V-Gan-25, V-Gan-50, Valium, valproic acid, Valrelease, valsartan, Valu-Dryl, Vanadom, Vanatrip, vardenafil, Vasodilan, vasopressin, Vasotec, VaZol, Velosulin BR, venlafaxine, venlafaxine extended release, Ventolin, Ventolin HFA, Ventolin Nebules, Ventolin Rotacaps, Veracolate, verapamil, verapamil 24 hour extended release, verapamil extended release, Verelan, Verelan PM, Versed, VESIcare, VFEND, Visken, Vistacon, Vistacot, Vistaject-50, Vistaril, Vistaril IM, Vistazine, Vistazine 50, Vivactil, Volmax, voriconazole, VoSpire ER, Wal-finate, Wytensin, X-Prep, Xanax, Xanax XR, Xopenex, Xopenex Concentrate, Xopenex HFA, Xyzal, XYZALL, Yutopar, Z-Pak, zaleplon, Zanaflex, Zarontin, Zaroxolyn, Zebeta, Zestril, Zetran, ziconotide, Zithromax, Zithromax IV, Zithromax TRI-PAK, Zithromax Z-Pak, Zmax, Zofran, Zofran ODT, Zoloft, zolpidem, zolpidem extended release, Zonalon, Zymine, Zymine XR, Zyprexa, Zyprexa Zydis, Zyrtec, Zyrtec Hives