Ferredoxin-nitrite reductase

In enzymology, a ferredoxin---nitrite reductase is an enzyme that catalyzes the chemical reaction


 * NH3 + 2 H2O + 6 oxidized ferredoxin $$\rightleftharpoons$$ nitrite + 6 reduced ferredoxin + 7 H+

The 3 substrates of this enzyme are NH3, H2O, and oxidized ferredoxin, whereas its 3 products are nitrite, reduced ferredoxin, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is ammonia:ferredoxin oxidoreductase. This enzyme participates in nitrogen metabolism. It has 3 cofactors: iron, Siroheme, and Iron-sulfur.

Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes, , and.