Endocarditis antithrombotic therapy


 * Associate Editors-in-Chief:

==Antithrombotic Therapy ==


 * Anticoagulants can cause or worsen hemorrhage in patients with endocarditis but may be carefully administered when needed
 * The prothrombin time should be carefully maintained at an INR of 2.0–3.0
 * Anticoagulation should be reversed immediately in the event of CNS complications and interrupted for 1–2 wk after an acute embolic stroke
 * Avoid heparin administration during active endocarditis if possible