2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

In enzymology, a 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase is an enzyme that catalyzes the chemical reaction


 * 2,3-dihydro-2,3-dihydroxybenzoate + NAD+ $$\rightleftharpoons$$ 2,3-dihydroxybenzoate + NADH + H+

Thus, the two substrates of this enzyme are 2,3-dihydro-2,3-dihydroxybenzoate and NAD+, whereas its 3 products are 2,3-dihydroxybenzoate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase. This enzyme is also called 2,3-DHB dehydrogenase. This enzyme participates in biosynthesis of siderophore group nonribosomal and.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.