1-alkyl-2-acetylglycerophosphocholine esterase

In enzymology, a 1-alkyl-2-acetylglycerophosphocholine esterase is an enzyme that catalyzes the chemical reaction


 * 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O $$\rightleftharpoons$$ 1-alkyl-sn-glycero-3-phosphocholine + acetate

Thus, the two substrates of this enzyme are 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine and H2O, whereas its two products are 1-alkyl-sn-glycero-3-phosphocholine and acetate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase. Other names in common use include 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase, and alkylacetyl-GPC:acetylhydrolase. This enzyme participates in ether lipid metabolism.

Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , and.