(heparan sulfate)-glucosamine 3-sulfotransferase 2

In enzymology, a [heparan sulfate]-glucosamine 3-sulfotransferase 2 is an enzyme that catalyzes the chemical reaction


 * 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine $$\rightleftharpoons$$ adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and [heparan sulfate]-glucosamine, whereas its two products are adenosine 3',5'-bisphosphate and [heparan sulfate]-glucosamine 3-sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase. Other names in common use include glucosaminyl 3-O-sulfotransferase, heparan sulfate D-glucosaminyl 3-O-sulfotransferase, and isoform/isozyme 2 (3-OST-2, HS3ST2). This enzyme participates in heparan sulfate biosynthesis and glycan structures - biosynthesis 1.