Alagille syndrome laboratory tests

Overview
In addition to various imaging modalities, laboratory tests may be conducted evaluating the bilirubin levels. A liver biopsy may also be conducted on the bile duct to further supplement bilirubin testing.

Biochemical Evaluation
Total Bilirubin >6.5 mg/dL, Conjugated Bilirubin >4.5 mg/dL, and cholesterol >520 mg/dL in children younger than 5 years of age are likely be associated with severe liver disease in later life.

Liver Biopsy
A liver biopsy may indicate too few bile ducts (bile duct paucity).

X ray
An unusual butterfly shape of the bones of the spinal column that can be seen in an x-ray