Pirlimycin

Pirlimycin hydrochloride belongs to the lincosamide class of antimicrobials. It is bacteriostatic and acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome. It is frequently used in the treatment of bovine mastitis caused by Gram-positive bacteria, specifically Staphylococcus aureus and coagulase negative species of Staphylococcus and Streptococcus. It has no activity against Gram-negative bacteria.