The Living Guidelines: STEMI Thienopyridines Suggest Revisions to the CLASS IIa Guidelines

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Class IIa Guidelines

 * 1) In patients <75 years of age who receive fibrinolytic therapy or who do not receive reperfusion therapy, it is reasonable to administer an oral loading dose of clopidogrel 300 mg. (Class IIa, Level of Evidence: C) (No data are available to guide decision making regarding an oral loading dose in patients 75 years of age or older).
 * 2) Long-term maintenance therapy (e.g., 1 year) with clopidogrel (75 mg / day orally) is reasonable in STEMI patients regardless of whether they undergo reperfusion with fibrinolytic therapy or do not receive reperfusion therapy. (Class IIa, Level of Evidence: C)