DGTPase

In enzymology, a dGTPase is an enzyme that catalyzes the chemical reaction


 * dGTP + H2O $$\rightleftharpoons$$ deoxyguanosine + triphosphate

Thus, the two substrates of this enzyme are dGTP and H2O, whereas its two products are deoxyguanosine and triphosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on triphosphoric monoester bonds. The systematic name of this enzyme class is dGTP triphosphohydrolase. Other names in common use include deoxy-GTPase, deoxyguanosine 5-triphosphate triphosphohydrolase, deoxyguanosine triphosphatase, and deoxyguanosine triphosphate triphosphohydrolase. This enzyme participates in purine metabolism.

Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes, , , and.