Histidinol-phosphatase

In enzymology, a histidinol-phosphatase is an enzyme that catalyzes the chemical reaction


 * L-histidinol phosphate + H2O $$\rightleftharpoons$$ L-histidinol + phosphate

Thus, the two substrates of this enzyme are L-histidinol phosphate and H2O, whereas its two products are L-histidinol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is L-histidinol-phosphate phosphohydrolase. Other names in common use include histidinol phosphate phosphatase, L-histidinol phosphate phosphatase, histidinolphosphate phosphatase, HPpase, and histidinolphosphatase. This enzyme participates in histidine metabolism.

Structural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes, , , , and.