Hyperviscosity syndrome

Overview
Hyperviscosity syndrome is an increase in the viscosity of the blood. This may be caused by an increase in serum proteins and may be associated with bleeding from mucous membranes, retinopathy, and especially monoclonal gammopathies such as Waldenström macroglobulinemia and in multiple myeloma. An increased viscosity secondary to polycythemia may be associated with organ congestion and decreased capillary perfusion.

Treatment
Plasmapheresis may be used to decrease viscosity.