FLP-FRT recombination

In genetics, FLP-FRT recombination is a site-directed recombination technology used to manipulate an organism's DNA under controlled conditions in vivo. It is analogous to Cre-Lox recombination. It involves the recombination of sequences between short (22 base pair) Flipase Recognition Target (FRT) sites by the Flipase recombination enzyme (FLP or Flp) derived from the yeast Saccharomyces cerevisiae.