Hypoplastic left heart syndrome causes


 * Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S.[mailto:psingh@perfuse.org],, Keri Shafer, M.D. [mailto:kshafer@bidmc.harvard.edu]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S.[mailto:kfeeney@perfuse.org]

Overview
As with most congenital heart defects, there is no known cause. Approximately 10% of patients with hypoplastic left heart syndrome also have other birth defects.

Causes
While many authorities believe the cause of hypoplastic left heart syndrome (HLHS) is unknown, recent research indicates that HLHS may be due to genetic factors.

There is evidence associating it with Gap junction protein, alpha 1.