Small nucleolar RNA SNORA48

Small nucleolar RNA SNORA48 is a pseudouridylation guide H/ACA box snoRNA. This snoRNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U3797 of 28S rRNA. The pseudouridylation of this residue was previously reported by Ofengand and Bakin (1997). The H/ACA box snoRNAs ACA48 and U67, and the C/D box snoRNA mgU6-77 share the same host gene (EIF4A1).