Bronidox

Bronidox® (Registered Tradmark of Cognis Corp) is chemical compound 5-Bromo-5-Nitro-1,3-Dioxane. Its use on goods without license from Cognis is strictly prohibited.


 * Formula: C4H6BrNO4
 * Synonyms:
 * 5-Brom-5-Nitro-1,3-Dioxan
 * 5-Bromo-5-nitro-m-Dioxan or 5-Bromo-5-nitro-m-Dioxane
 * 1,3-Dioxane, 5-Bromo-5-Nitro-
 * BRONIDOX® L5
 * BRONIDOX® L
 * Molecular weight: 212.06.


 * Color:
 * white crystalline powder
 * colourless, transparent liquid in 1,2-propylene glycol
 * Melting point: 60 °C or 58.5-62°C
 * Light sensitive.
 * Solubility: insoluble in water
 * pH: 6-7
 * Stable under normal conditions
 * Non reactive with enzyme/substrate in assays but causes inhibition of enzyme activity n Bacteria
 * BRONIDOX® L5 is corrosive on metals
 * ??? Incompabilities: strong oxidizing agents ???


 * CAS Number: 30007-47-7
 * EINECS Number: 250-001-7

Used as

 * Stabilizer
 * Surfactant
 * It is used in immunology for preserving antibodies and antisera in 0.1 - 0.5% concentration. It is used as preservative to avoid use of sodium azide.
 * Bactericide. Very effective against yeast and fungi.
 * used in cosmetics since the mid-1970s as preservative for shampoos, foam bath, etc. Maximum concentration is 0.1 %.

Safety

 * Harmful
 * Harmful if swallowed
 * Toxic - tremor, convulsions, excitement
 * Irritating to skin - dermatitis
 * wear suitable protective clothing
 * relatively non-toxic to mammals
 * some users do not recommend use in preparations destined for in vivo or tissue culture work


 * Combustion products: carbon monoxide, carbon dioxide, nitrogen oxides, hydrogen bromide gas, sulphur oxides, hydrogen chloride gas

Toxicology
according to FSASAX
 * Oral:
 * LD50, mouse, oral 590 mg/kg 24 hours
 * LD50, rat, oral 455 mg/kg 24 hours


 * LD50, rat, ipr. 31 mg/kg 24 hours


 * Skin:
 * LD50, mouse, skin 2500 µg/24 hours
 * LD50, rat, skin 2500 µg/24 hours