Ventricular septal defect causes

and Leida Perez, M.D.

Associate Editor-In-Chief: Keri Shafer, M.D. [mailto:kshafer@bidmc.harvard.edu],Atif Mohammad, M.D., Priyamvada Singh, MBBS

Causes-


 * The causes of VSD are not yet known. This defect often occurs along with other congenital heart defects.


 * In adults, ventricular septal defects are a rare but serious complication of heart attacks. These holes are related to heart attacks and do not result from a birth defect.


 * Genetics - The frequent association between arch abnormalities and significant conal VSDs suggests a common mechanism involving a chromosome band 22q11 microdeletion. Deletions in this area have not been linked with isolated supracristal VSDs.