Guanosine diphosphate

Guanosine diphosphate, abbreviated GDP, is a nucleotide. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase guanine.

GDP is the product of GTP dephosphorylation by GTPases, e.g. the G-proteins that are involved in signal transduction.

Biologicaly GDP is converted into GTP with the help of pyruvate kinase and phosphoenolpyruvate