Latanoprost precautions

List of precautions
General Contact Lenses Bacterial Keratitis Intraocular Inflammation Macular edema Nursing Mothers Pediatric Use Geriatric Use

General
Latanoprost is hydrolyzed in the cornea. The effect of continued administration of XALATAN Sterile Ophthalmic Solution on the corneal endothelium has not been fully evaluated. Return to top

Contact Lenses
XALATAN should not be administered while wearing contact lenses. Return to top

Bacterial Keratitis
There have been reports of bacterial keratitis associated with the use of multiple-dose containers of topical ophthalmic products. These containers had been inadvertently contaminated by patients who, in most cases, had a concurrent corneal disease or a disruption of the ocular epithelial surface. Return to top

Intraocular Inflammation
XALATAN should be used with caution in patients with active intraocular inflammation. Return to top (iritis/uveitis)

Macular edema
Macular edema, including cystoid macular edema, has been reported during treatment with XALATAN. These reports have mainly occurred in aphakic patients, in pseudophakic patients with a torn posterior lens capsule, or in patients with known risk factors for macular edema. XALATAN should be used with caution in these patients. Return to top

Nursing Mothers
It is not known whether this drug or its metabolites are excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when XALATAN is administered to a nursing woman. Return to top

Pediatric Use
Safety and effectiveness in pediatric patients have not been established. Return to top

Geriatric Use
No overall differences in safety or effectiveness have been observed between elderly and younger patients. Return to top