Soluble epoxide hydrolase

In enzymology, a soluble epoxide hydrolase is an enzyme that catalyzes the chemical reaction


 * an epoxide + H2O $$\rightleftharpoons$$ a glycol

Thus, the two substrates of this enzyme are epoxide and H2O, whereas its product is glycol.

This enzyme belongs to the family of hydrolases, specifically those acting on ether bonds (ether hydrolases). The systematic name of this enzyme class is epoxide hydrolase. Other names in common use include epoxide hydrase (ambiguous), epoxide hydratase (ambiguous), arene-oxide hydratase (ambiguous), aryl epoxide hydrase (ambiguous), trans-stilbene oxide hydrolase, sEH, and cytosolic epoxide hydrolase. This enzyme participates in arachidonic acid metabolism and tetrachloroethene degradation.