Contrast induced encephalopathy

Retention of contrast in the brain is rare, and has been documented in only a handful of cases. Contrast induced encephalopathy is also a rare disorder in which an encephalopathy occurs following iodinated contrast injections. It has been observed following angioplasty. It is associated with diffuse slowing on the EEG. The disorder is usually self limited and resolves within 24 hours. Patients with impaired creatinine clearance may be at increased risk for the disorder. Treatment is largely supportive, although one small study of 3 patients reports that craniectomy was successfully used to reduce cerebral edema.