Donor lymphocyte infusion

Overview
Donor lymphocyte infusion (DLI) is a form of adoptive immunotherapy used after hematopoietic stem cell transplantation. Lymphocytes from the original stem cell donor are infused, after the transplant, to augment an anti-tumor immune response or ensure that the donor stem cells remain engrafted. Complications of DLI include acute and chronic graft-versus-host disease and bone marrow aplasia, resulting in immunosuppression and susceptibility to opportunistic infections.