Decylhomocitrate synthase

In enzymology, a decylhomocitrate synthase is an enzyme that catalyzes the chemical reaction


 * dodecanoyl-CoA + H2O + 2-oxoglutarate $$\rightleftharpoons$$ (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA

The 3 substrates of this enzyme are dodecanoyl-CoA, H2O, and 2-oxoglutarate, whereas its two products are (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate and CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming). Other names in common use include 2-decylhomocitrate synthase, 3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase, and (CoA-acylating).