The Living Guidelines: STEMI Antiplatelet Therapy View the Current CLASS I Guidelines

1. Clopidogrel 75 mg per day orally should be added to aspirin in patients with STEMI regardless of whether they undergo reperfusion with fibrinolytic therapy or do not receive reperfusion therapy. (Class I, Level of Evidence: A) Treatment with clopidogrel should continue for at least 14 days. (Class I, Level of Evidence: B)

2. In patients taking clopidogrel in whom CABG is planned, the drug should be withheld for at least 5 days and preferably for 7 days unless the urgency for revascularization outweighs the risks of excess bleeding. (Class I, Level of Evidence: B)