Cholesterol side-chain cleavage enzyme

P450 scc (or 20,22-Desmolase) is an enzyme associated with the conversion of cholesterol to pregnenolone. The terminology "Desmolase" is becoming outdated and the enzyme is now more commonly referred to as P450scc.

The "scc" refers to side chain cleavage.

Pathology
A deficiency can lead to lipoid congenital adrenal hyperplasia. However, this is very rare.