Mycobacterium goodii

Mycobacterium goodii

Description
Gram-positive, nonmotile and acid-fast rods.

Colony characteristics
 * Smooth to mucoid, off-white to cream coloured colonies. Yellow to orange pigment produced in 78% of all strains, after 10-14 days incubation.

Physiology
 * Rapid growth on Middlebrook 7H10 and trypticase soy agar at 30°C, 35°C and 45°C within 2-4 days.
 * Susceptible to amikacin, ethambutol, sulfamethoxazole.
 * Intermediate susceptible to ciprofloxacin, doxycycline and tobramycin.
 * Variable susceptible to cefmetazole, cefoxitin and clarithromycin.
 * Resistant to isoniazid and rifampicin.

Differential characteristics
 * Comparable clinical settings to M. smegmatis and members of the M. fortuitum complex.

Pathogenesis

 * Production of post-traumatic wound infections especially those following open fractures and with associated osteomyelitis and chronic lipoid pneumonia.

Type Strain
First isolated from a patient with a post-traumatic osteomyelitis of the heel(USA). Strain MO69 = ATCC 700504 = CIP 106349 = DSM 44492 = JCM 12689. Mycobacterium goodii was previously known as Mycobacterium smegmatis group 2.