Phosphatidate phosphatase

In enzymology, a phosphatidate phosphatase is an enzyme that catalyzes the chemical reaction


 * a 3-sn-phosphatidate + H2O $$\rightleftharpoons$$ a 1,2-diacyl-sn-glycerol + phosphate

Thus, the two substrates of this enzyme are 3-sn-phosphatidate and H2O, whereas its two products are 1,2-diacyl-sn-glycerol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is 3-sn-phosphatidate phosphohydrolase. Other names in common use include phosphatic acid phosphatase, acid phosphatidyl phosphatase, and phosphatic acid phosphohydrolase. This enzyme participates in 4 metabolic pathways: glycerolipid metabolism, glycerophospholipid metabolism, ether lipid metabolism, and sphingolipid metabolism.