Chinese hamster ovary cell

Chinese Hamster Ovary cells (CHO cells) are a cell line derived from Chinese Hamster ovary cells. They are often used in biological and medical research. They were introduced in the 1960s and are used in a cultured monolayer in culture flasks. They require the amino acid proline in their culture medium; this property makes them ideal for genetics research. CHO cells are used in studies of genetics, toxicity screening, nutrition and gene expression particularly expression of recombinant proteins.