Shikimate kinase

In enzymology, a shikimate kinase is an enzyme that catalyzes the chemical reaction


 * ATP + shikimate $$\rightleftharpoons$$ ADP + shikimate 3-phosphate

Thus, the two substrates of this enzyme are ATP and shikimate, whereas its two products are ADP and shikimate 3-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:shikimate 3-phosphotransferase. Other names in common use include shikimate kinase (phosphorylating), and shikimate kinase II. This enzyme participates in phenylalanine, tyrosine and tryptophan biosynthesis.

Structural studies
As of late 2007, 26 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , , , , , , , , , , , , , , , and.

Human proteins containing this domain
MAPK7;    THNSL1;