4-hydroxymandelate synthase

In enzymology, a 4-hydroxymandelate synthase is an enzyme that catalyzes the chemical reaction


 * 4-hydroxyphenylpyruvate + O2 $$\rightleftharpoons$$ 4-hydroxymandelate + CO2

Thus, the two substrates of this enzyme are 4-hydroxyphenylpyruvate and O2, whereas its two products are 4-hydroxymandelate and CO2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating). This enzyme is also called 4-hydroxyphenylpyruvate dioxygenase II.