Aseptic meningitis historical perspective


 * Associate Editor-In-Chief:

Overview
Wallgren coined the term aseptic meningitis in 1925 and defined it as a disease with acute onset that had typical systematic symptoms of meningeal involvement, in association with a cerebrospinal fluid (CSF) typical of meningitis (typically with a mononuclear cell predominance). Additionally, there was absence of bacteria on stain and culture and there was no identifiable parameningeal infection.