5,10-methenyltetrahydromethanopterin hydrogenase

In enzymology, a 5,10-methenyltetrahydromethanopterin hydrogenase is an enzyme that catalyzes the chemical reaction


 * H2 + 5,10-methenyltetrahydromethanopterin $$\rightleftharpoons$$ H+ + 5,10-methylenetetrahydromethanopterin

Thus, the two substrates of this enzyme are H2 and 5,10-methenyltetrahydromethanopterin, whereas its two products are H+ and 5,10-methylenetetrahydromethanopterin.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other, known, acceptors. The systematic name of this enzyme class is hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase. Other names in common use include H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase, nonmetal hydrogenase, N5,N10-methenyltetrahydromethanopterin hydrogenase, and hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.