Case series

A case series (also known as a clinical series) is a medical research study that tracks patients with a known exposure given similar treatment or examines their medical records for exposure and outcome.

A case series can be retrospective or prospective and usually involves a smaller number of patients than more powerful case-control studies or randomized controlled trials.

A case series is a type of observational study. Case series may be consecutive or non-consecutive, depending on whether all cases presenting to the reporting authors over a period of time were included, or only a selection.

Case series may be confounded by selection bias, which limits statements on the causality of correlations observed.