Non-Cardiac Reasons of Troponin Elevation

Pacing

 * Implantable cardioverter defibrillator firings including


 * Atrial defibrillators


 * Cardioversion

Cardiac surgery
===Interventional closure of atrial septal defects

Hypertrophic obstructive cardiomyopathy
with significant left ventricular hypertrophy

Hypotension
often with arrhythmias

Postoperative non cardiac surgery patients
who seem to do well

Critically ill patients
especially those who have diabetes,

respiratory failure,

gastrointestinal bleeding,

sepsis

Drug toxicity
doxorubicin,

5-fluorouracil,

trastuzumab,

snake venoms,

carbon monoxide poisoning

Abnormalities in coronary vasomotion
including coronary vasospasm

Inflammatory diseases
myocarditis,

parvovirus B19,

Kawasaki disease
,

sarcoid,

smallpox vaccination,

myocardial extension of bacterial endocarditis)

Burns
Especially if total body surface area is more than 30%

==Infiltrative diseases

amyloidosis,
hemochromatosis, sarcoidosis and scleroderma

==Acute neurologic disease, including cerebrovascular accidents, subarachnoid bleeds

==Rhabdomyolysis with cardiac injury

==Transplant vasculopathy

==Vital exhaustion

Reference:

1. K. Saenger A. K., Jaffe A. S., The Use of Biomarkers for the Evaluation and Treatment of Patients with Acute Coronary Syndromes, Med Clin N Am 91 (2007) 657–681