Bis-HPPP

Bis-hppp is an acronym for 2,2-bis [4(2,3 hydroxypropoxy) phenyl] propane.

Molecular Formula: C21H28O6

Molecular Weight: 376.44

This monomer (bis-HPPP) and Methcrylic Acid (MA) are released following the CE-catalyzed hydrolysis of 2,2-[4(2-hydroxy 3-methacryloxypropoxy)-phenyl] propane (bis-GMA). This reaction is very common in hydrolytic degradation of the dental resin since salivary esterases are able to cleave the ester bonds in Acrylic polymers of dental composites. Mass Spectra (MS) analysis demonstrated that hydrolytic reactions would cleave the ester bonds of both methacrylate units in bis-GMA and produce bis-HPPP along with two molecules MA (Finer Y, S.J., The influence of resin chemistry on a dental composite's biodegradation. J Biomed Mater Res, 2004. 69A: p. 233-246).