Polyphosphate kinase

In enzymology, a polyphosphate kinase is an enzyme that catalyzes the chemical reaction


 * ATP + (phosphate)n $$\rightleftharpoons$$ ADP + (phosphate)n+1

Thus, the two substrates of this enzyme are ATP and (phosphate)n, whereas its two products are ADP and (phosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:polyphosphate phosphotransferase. This enzyme is also called polyphosphoric acid kinase. This enzyme participates in oxidative phosphorylation.

Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes, , and.