Amoxicillin instructions for administration

Instructions for administration
General H. pylori eradication to reduce the risk of duodenal ulcer recurrence Triple therapy Dual therapy Dosing recommendations for adults with impaired renal function Directions for Mixing Oral Suspension Directions for Mixing Pediatric Drops

General
It should be recognized that in the treatment of chronic urinary tract infections, frequent bacteriological and clinical appraisals are necessary. Smaller doses than those recommended above should not be used. Even higher doses may be needed at times. In stubborn infections, therapy may be required for several weeks. It may be necessary to continue clinical and/or bacteriological follow-up for several months after cessation of therapy. Except for gonorrhea, treatment should be continued for a minimum of 48 to 72 hours beyond the time that the patient becomes asymptomatic or evidence of bacterial eradication has been obtained. It is recommended that there be at least 10 days’ treatment for any infection caused by Streptococcus pyogenes to prevent the occurrence of acute rheumatic fever. Return to top

H. pylori eradication to reduce the risk of duodenal ulcer recurrence Triple therapy
AMOXIL/clarithromycin/lansoprazole The recommended adult oral dose is 1 gram AMOXIL, 500 mg clarithromycin, and 30 mg lansoprazole, all given twice daily (q12h) for 14 days. Return to top

Dual therapy
AMOXIL/lansoprazole The recommended adult oral dose is 1 gram AMOXIL and 30 mg lansoprazole, each given three times daily (q8h) for 14 days. Return to top

Dosing recommendations for adults with impaired renal function
Patients with impaired renal function do not generally require a reduction in dose unless the impairment is severe. Severely impaired patients with a glomerular filtration rate of <30 mL/min. should not receive the 875-mg tablet. Patients with a glomerular filtration rate of 10 to 30 mL/min. should receive 500 mg or 250 mg every 12 hours, depending on the severity of the infection. Patients with a less than 10 mL/minute glomerular filtration rate should receive 500 mg or 250 mg every 24 hours, depending on severity of the infection. Hemodialysis patients should receive 500 mg or 250 mg every 24 hours, depending on severity of the infection. They should receive an additional dose both during and at the end of dialysis. Return to top

Directions for Mixing Oral Suspension
Tap bottle until all powder flows freely. Add approximately 1/3 of the total amount of water for reconstitution (see table below) and shake vigorously to wet powder. Add remainder of the water and again shake vigorously. Return to top

Directions for Mixing Pediatric Drops
Add the required amount of water (see table below) to the bottle and shake vigorously. 452 Each mL of suspension will then contain amoxicillin trihydrate equivalent to 50 mg amoxicillin. Return to top