Fibroblast growth factor receptor 2

Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor on chromosome 10.

Clinical significance
Mutations (changes) are associated with several medical condition:


 * Apert syndrome, the best-known type of acrocephalosyndactyly. This condition is characterized by abnormalities of the skull and face and the hands and feet.


 * Pfeiffer syndrome (another type of acrocephalosyndactyly). Inherited as dominant trait.
 * Crouzon syndrome (purely a craniofacial disorder with no hand or foot problems). Inherited as dominant trait.
 * Jackson-Weiss syndrome
 * Breast cancer