The Living Guidelines: Renin-Angiotensin-Aldosterone System Blockers: ACE Inhibitors Suggest Revisions to the CLASS I Guidelines

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Class I Guidelines

 * 1) ACE inhibitors should be started and continued indefinitely in all patients with LVEF ≤40% and (changed text) for those with hypertension, diabetes, or chronic kidney disease, unless contraindicated. (Class I Level of Evidence: A)
 * 2) ACE inhibitors should be started and continued indefinitely in patients who are not lower risk (lower risk defined as those with normal LVEF in whom cardiovascular risk factors are well controlled and revascularization has been performed), unless contraindicated. (Class I Level of Evidence: B)