Germinoma other diagnostic studies

Biopsy
The diagnosis of an intracranial germinoma usually is based on biopsy, because the features on neuroimaging are similar to other tumors.

Intracranial germinomas have a reported 90% survival to five years after diagnosis. Near total resection does not seem to influence the cure rate, so gross total resection is not necessary and can increase the risk of complications from surgery. The best results have been reported from craniospinal radiation with local tumor boost of greater than 4,000 cGy.