Fumarase

Fumarase (or fumarate hydratase) is an enzyme involved in the Krebs Cycle (aka the Tricarboxylic Acid Cycle aka the Citric Acid Cycle) that catalyzes the hydration (addition of H2O across a double bond) of Fumarate to L-malate (See the entry on optical isomer).

Fumarate + H2O <->  L Malate

Biochemical Pathway

 * Diagram TCA Cycle at KEGG, gives some details on the TCA cycle in which fumerase acts. [Fumarase is labeled '4.2.1.2' in the lower left hand corner of this diagram.


 * structure of Fumarate
 * Structure of L Malate


 * See also Citric Acid Cycle on Wikipedia.