(isocitrate dehydrogenase (NADP+)) kinase

In enzymology, a [isocitrate dehydrogenase (NADP+)] kinase is an enzyme that catalyzes the chemical reaction


 * ATP + [isocitrate dehydrogenase (NADP+)] $$\rightleftharpoons$$ ADP + [isocitrate dehydrogenase (NADP+)] phosphate

Thus, the two substrates of this enzyme are ATP and [isocitrate dehydrogenase (NADP+)], whereas its two products are ADP and [isocitrate dehydrogenase (NADP+)] phosphate.

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[isocitrate dehydrogenase (NADP+)] phosphotransferase. Other names in common use include [isocitrate dehydrogenase (NADP+)] kinase, ICDH kinase/phosphatase, IDH kinase, IDH kinase/phosphatase, IDH-K/P, IDHK/P, isocitrate dehydrogenase kinase (phosphorylating), isocitrate dehydrogenase kinase/phosphatase, and STK3. This enzyme participates in mapk signaling pathway.