Flavonol 3-O-glucosyltransferase

In enzymology, a flavonol 3-O-glucosyltransferase is an enzyme that catalyzes the chemical reaction


 * UDP-glucose + a flavonol $$\rightleftharpoons$$ UDP + a flavonol 3-O-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and flavonol, whereas its two products are UDP and flavonol 3-O-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol 3-O-D-glucosyltransferase. Other names in common use include GTI, uridine diphosphoglucose-flavonol 3-O-glucosyltransferase, UDP-glucose:flavonol 3-O-glucosyltransferase, and UDPG:flavonoid-3-O-glucosyltransferase. This enzyme participates in flavonoid biosynthesis.

Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes, , and.