GISSI

The Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI) (Italian group for the study of the survival of Myocardial Infarction) is an influential cardiology research group founded as a collaboration between two Italian organisations – the Mario Negri Institute and the Associazione Nazionale dei Medici Cardiologi Ospedalieri (ANMCO). The trials carried out by GISSI have "obtained wide recognition in the international world of cardiology and are considered a methodological landmark". Four large-scale clinical trials over the past 20 years (GISSI 1, GISSI 2  , GISSI 3 , GISSI Prevention ) have involved more than 60,000 patients with acute myocardial infarction (AMI).