Thiamine-triphosphatase

In enzymology, a thiamine-triphosphatase is an enzyme that catalyzes the chemical reaction


 * thiamine triphosphate + H2O $$\rightleftharpoons$$ thiamine diphosphate + phosphate

Thus, the two substrates of this enzyme are thiamine triphosphate and H2O, whereas its two products are thiamine diphosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is thiamine-triphosphate phosphohydrolase. This enzyme participates in thiamine metabolism.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.