Geissoschizine dehydrogenase

In enzymology, a geissoschizine dehydrogenase is an enzyme that catalyzes the chemical reaction


 * geissoschizine + NADP+ $$\rightleftharpoons$$ 4,21-didehydrogeissoschizine + NADPH

Thus, the two substrates of this enzyme are geissoschizine and NADP+, whereas its two products are 4,21-didehydrogeissoschizine and NADPH.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is geissoschizine:NADP+ 4,21-oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis.