UDP-glucuronate 5'-epimerase

In enzymology, an UDP-glucuronate 5'-epimerase is an enzyme that catalyzes the chemical reaction


 * UDP-glucuronate $$\rightleftharpoons$$ UDP-L-iduronate

Hence, this enzyme has one substrate, UDP-glucuronate, and one product, UDP-L-iduronate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is UDP-glucuronate 5'-epimerase. Other names in common use include uridine diphosphoglucuronate 5'-epimerase, UDP-glucuronic acid 5'-epimerase, and C-5-uronosyl epimerase. This enzyme participates in nucleotide sugars metabolism. It employs one cofactor, NAD+.