Deoxyuridine phosphorylase

In enzymology, a deoxyuridine phosphorylase is an enzyme that catalyzes the chemical reaction


 * 2'-deoxyuridine + phosphate $$\rightleftharpoons$$ uracil + 2-deoxy-alpha-D-ribose 1-phosphate

Thus, the two substrates of this enzyme are 2'-deoxyuridine and phosphate, whereas its two products are uracil and 2-deoxy-alpha-D-ribose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is 2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase. This enzyme participates in pyrimidine metabolism.