HLA-DR5

HLA-DR5 (DR5) is a broad-antigen serotype that is further split into HLA-DR11 and HLA-DR12 antigen serotypes.

=Serology=

With the exception of a few DRB1* alleles the reactivity of DR5 is relatively poor.

=Disease associations= DR5 is associated with persistent generalized lymphadenopathy (PGL) and Kaposi sarcoma in AIDS, juvenile rheumatoid arthritis , Hashimoto's thyroiditis  , mycosis fungoides , polyglandular deficiency syndrome , systemic sclerosis  , childhood epilepsy ,  early-onset alopecia areata , short-ragweed Ra6 allergy , primary antiphospholipid syndrome , and increased longevity in the Dutch

=Genetic linkage= HLA-DR5 reactive gene products are linked to serology of HLA-DRB3 (HLA-DR52).

=References=