Zinke nitration

The Zinke nitration is an organic reaction in which a bromine substituent of a phenol or cresol is replaced by a nitro group by treatment with nitrous acid or sodium nitrite. The reaction is a manifestation of nucleophilic aromatic substitution.

Two examples:

and:



The Zincke nitration should not be confused with the Zincke-Suhl reaction or the Zincke reaction.