Mirtazapine

Synonyms / Brand Names: Mirtazapina, Mirtazapinum, Mirtazepine, Mepirzepine, Remeron, Remeron Soltab, Zispin, Remergil, Norset, Rexer, Remergon, Mirtabene, Avanza, Mirtazon, Axit, Mirtaz, Promyrtil

Dosing and Administration
The recommended starting dose for Mirtazapine tablets USP is 15 mg/day, administered in a single dose, preferably in the evening prior to sleep. In the controlled clinical trials establishing the efficacy of Mirtazapine in the treatment of major depressive disorder, the effective dose range was generally 15 mg/day to 45 mg/day. While the relationship between dose and satisfactory response in the treatment of major depressive disorder for Mirtazapine has not been adequately explored, patients not responding to the initial 15 mg dose may benefit from dose increases up to a maximum of 45 mg/day. Mirtazapine has an elimination half-life of approximately 20 to 40 hours, therefore, dose changes should not be made at intervals of less than one to two weeks in order to allow sufficient time for evaluation of the therapeutic response to a given dose.

FDA Package Insert Resources Indications, Contraindications, Side Effects, Drug Interactions, etc. Calculate Creatine Clearance On line calculator of your patients Cr Cl by a variety of formulas. Convert pounds to Kilograms On line calculator of your patients weight in pounds to Kg for dosing estimates. Publication Resources Recent articles, WikiDoc State of the Art Review, Textbook Information Trial Resources Ongoing Trials, Trial Results Guidelines & Evidence Based Medicine Resources US National Guidelines, Cochrane Collaboration, etc. Media Resources Slides, Video, Images, MP3, Podcasts, etc. Patient Resources Discussion Groups, Handouts, Blogs, News, etc. International Resources en Español

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Trial Resources
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