Transposition of the great vessels epidemiology and demographics


 * Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [mailto:psingh@perfuse.org]; ; Keri Shafer, M.D. [mailto:kshafer@bidmc.harvard.edu]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [mailto:kfeeney@perfuse.org]

Overview
Transposition of the great arteries most commonly present within first 24 hours of life

Epidemiology and demographics

 * Transposition of the great arteries TGA is one of the commonest cyanotic congenital heart defects present in the first 24 hours of life.
 * An incidence at birth of 20-30 in 100000 live births
 * TGA represents 5-7% of all CHD.
 * Almost 20 percent of all cyanotic CHD defects
 * TGA is more common in infants of diabetic mothers.
 * Boys outnumber girls with an approximate ratio of 2:1.
 * Without treatment, 30% of infants die within the first week of life, 50% will die in the first month, 70% will die in the first 6 months and 90% of infants will die before the end of the first year.