Meromyosin

Meromyosin are subunits of myosin formed by trypsin digestion. It comes in two types, heavy meromyosin (HMM) and light meromyosin (LMM).

Light meromyosin - long, straight portion, “tail” region

Heavy meromyosin Protein chain terminating in globular head portion - cross bridge

Essential and regulatory light chains

Actin binding site ATP binding site (myosin ATPase) – determines rate of muscle contraction when muscle is stretched