N-acyl-D-amino-acid deacylase

In enzymology, a N-acyl-D-amino-acid deacylase is an enzyme that catalyzes the chemical reaction


 * N-acyl-D-amino acid + H2O $$\rightleftharpoons$$ an acid + D-amino acid

Thus, the two substrates of this enzyme are N-acyl-D-amino acid and H2O, whereas its two products are acid and D-amino acid.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-acyl-D-amino acid amidohydrolase. It employs one cofactor, zinc.

Structural studies
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , and.