Aminodeoxychorismate synthase

In enzymology, an aminodeoxychorismate synthase is an enzyme that catalyzes the chemical reaction


 * chorismate + L-glutamine $$\rightleftharpoons$$ 4-amino-4-deoxychorismate + L-glutamate

Thus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its two products are 4-amino-4-deoxychorismate and L-glutamate.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is chorismate:L-glutamine amido-ligase. Other names in common use include ADC synthase, 4-amino-4-deoxychorismate synthase, and PabB. This enzyme participates in folate biosynthesis.