Hepatic lipase

Hepatic lipase is a form of lipase. It is expressed in the liver and adrenal glands.

Clinical significance
Hepatic lipase deficiency is a rare, autosomal recessive disorder that results in elevated high density lipoprotein (HDL) cholesterol due to a mutation in the hepatic lipase gene. Clinical features are not well understood and there are no characteristic xanthomas. There is an association with a delay in atherosclerosis in an animal model.