Manganese peroxidase

In enzymology, a manganese peroxidase is an enzyme that catalyzes the chemical reaction


 * 2 Mn(II) + 2 H+ + H2O2 $$\rightleftharpoons$$ 2 Mn(III) + 2 H2O

The 3 substrates of this enzyme are Mn(II), H+, and H2O2, whereas its two products are Mn(III) and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a peroxide as acceptor (peroxidases). The systematic name of this enzyme class is Mn(II):hydrogen-peroxide oxidoreductase. Other names in common use include peroxidase-M2, and Mn-dependent (NADH-oxidizing) peroxidase. It employs one cofactor, heme.

Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes, , , , , and.