Staphylococcal scalded skin syndrome

Staphylococcal scalded skin syndrome, SSSS, also known as Pemphigus neonatorum or Ritter's disease, is a dermatological condition caused by Staphylococcus aureus.

Pathophysiology
The syndrome is induced by 2 epidermolytic exotoxins A and B, which are released by S. aureus and cause the epidermis to detach from the underlying dermis. One of the exotoxins is produced by the bacterial chromosome, while the other is produced by a plasmid. (Bacterial plasmids are pieces of self-replicating DNA that often code for secondary characteristics, such as antibiotic resistance, and toxin production.)

Symptoms
The disease presents with the widespread formation of fluid filled blisters that are thin walled and easily ruptured. Ritter's Disease of the Newborn is the most severe form of SSSS with similar signs and symptoms.

Staphylococcal scalded skin syndrome 伝染性膿痂疹 Staphylococcal scalded skin syndrome

Choroba Rittera