Detoxication

The major metabolites formed from most drug metabolism are detoxication products. There are two common patterns observed:
 * 1) A drug with potent pharmacological activity is converted to a major metabolite with markedly reduced or no pharmacological activity (e.g., Pentobarbital and Hydroxypentobarbital)
 * 2) A drug is converted to a metabolite with roughly equivalent or slightly lower pharmacological activity.