D-amino acid oxidase

D-amino acid oxidase (DAAO) is a peroxisomal enzyme containing FAD as cofactor spread from yeasts to human. It is not present in bacteria nor in plants. Its function is to oxidize D-amino acids to the corresponding imino acids producing ammonia and oxygen peroxide. Recently mammalian D-amino acid has been connected to the brain D-serine metabolism and to the regulation of the glutamatergic neurotransmission.