Basedow syndrome

Karl Adolph von Basedow was the first doctor to describe Basedow Syndrome, which is characterized by a triad of hyperthyroidism, Goitre, and exophthalmos (bulging eyeballs).

Symptoms
Symptoms include:

cardiac arrhythmias increased pulse rate weight loss in the presence of increased appetite intolerance to heat elevated basal metabolism rate profuse sweating weakness elevated protein-bound iodine level tremor eyelid retraction and stare.

Cause
It is unknown, but it may be related to an autoimmune malfunction or disease. The ratio of onset is 4:1 in females. It is normally discovered in the third or fourth decade of life.