Ziac side effects

Side effects
Bisoprolol Fumarate
 * Central Nervous System
 * Cardiovascular
 * Gastrointestinal
 * Musculoskeletal
 * Skin
 * Special Senses
 * Metabolic
 * Respiratory
 * Genitourinary
 * General
 * Central Nervous System
 * Allergic
 * Hematologic
 * Gastrointestinal
 * Miscellaneous

Hydrochlorothiazide
 * General
 * Cardiovascular
 * Gastrointestinal
 * Musculoskeletal
 * Special Senses
 * Metabolic
 * Genitourinary
 * Gastrointestinal

Bisoprolol Fumarate
In clinical trials worldwide, or in postmarketing experience, a variety of other AEs, in addition to those listed above, have been reported. While in many cases it is not known whether a causal relationship exists between bisoprolol and these AEs, they are listed to alert the physician to a possible relationship. Return to top

Central Nervous System(Bisoprolol Fumarate)
Unsteadiness, dizziness, vertigo, headache, syncope, paresthesia, hypoesthesia, hyperesthesia, sleep disturbance/vivid dreams, insomnia, somnolence, depression, anxiety/restlessness, decreased concentration/memory. Return to top

Cardiovascular(Bisoprolol Fumarate)
Bradycardia, palpitations and other rhythm disturbances, cold extremities, claudication, hypotension, orthostatic hypotension, chest pain, congestive heart failure, dyspnea on exertion. Return to top

Gastrointestinal(Bisoprolol Fumarate)
Gastric/epigastric/abdominal pain, peptic ulcer, gastritis, dyspepsia, nausea, vomiting, diarrhea, constipation, dry mouth. Return to top

Musculoskeletal(Bisoprolol Fumarate)
Arthralgia, muscle/joint pain, back/neck pain, muscle cramps, twitching/tremor. Return to top

Skin(Bisoprolol Fumarate)
Rash, acne, eczema, psoriasis, skin irritation, pruritus, purpura, flushing, sweating, alopecia, dermatitis, exfoliative dermatitis (very rarely), cutaneous vaculitis. Return to top

Special Senses(Bisoprolol Fumarate)
Visual disturbances, ocular pain/pressure, abnormal lacrimation, tinnitus, decreased hearing, earache, taste abnormalities. Return to top

Metabolic(Bisoprolol Fumarate)
Gout. Return to top

Respiratory(Bisoprolol Fumarate)
Asthma, bronchospasm, bronchitis, dyspnea, pharyngitis, rhinitis, sinusitis, URI (upper respiratory infection). Return to top

Genitourinary(Bisoprolol Fumarate)
Decreased libido/impotence, Peyronie’s disease (very rarely), cystitis, renal colic, polyuria. Return to top

General(Bisoprolol Fumarate)
Fatigue, asthenia, chest pain, malaise, edema, weight gain, angioedema. In addition, a variety of adverse effects have been reported with other beta-adrenergic blocking agents and should be considered potential adverse effects. Return to top

Central Nervous System(Bisoprolol Fumarate)
Reversible mental depression progressing to catatonia, hallucinations, an acute reversible syndrome characterized by disorientation to time and place, emotional lability, slightly clouded sensorium. Return to top

Allergic(Bisoprolol Fumarate)
Fever, combined with aching and sore throat, laryngospasm, and respiratory distress. Return to top

Hematologic(Bisoprolol Fumarate)
Agranulocytosis, thrombocytopenia. Return to top

Gastrointestinal(Bisoprolol Fumarate)
Mesenteric arterial thrombosis and ischemic colitis. Return to top

Miscellaneous(Bisoprolol Fumarate)
The oculomucocutaneous syndrome associated with the beta-blocker practolol has not been reported with bisoprolol fumarate during investigational use or extensive foreign marketing experience. Return to top

Hydrochlorothiazide
The following adverse experiences, in addition to those listed in the above table, have been reported with hydrochlorothiazide (generally with doses of 25 mg or greater). Return to top

General (Hydrochlorothiazide)
Weakness. Return to top

Central Nervous System (Hydrochlorothiazide)
Vertigo, paresthesia, restlessness. Return to top

Cardiovascular(Hydrochlorothiazide)
Orthostatic hypotension (may be potentiated by alcohol, barbiturates, or narcotics). Return to top

Gastrointestinal(Hydrochlorothiazide)
Anorexia, gastric irritation, cramping, constipation, jaundice (intrahepatic cholestatic jaundice), pancreatitis, cholecystitis, sialadenitis, dry mouth. Return to top

Musculoskeletal(Hydrochlorothiazide)
Muscle spasm. Return to top

Hypersensitive Reactions(Hydrochlorothiazide)
Purpura, photosensitivity, rash, urticaria, necrotizing angiitis (vasculitis and cutaneous vasculitis), fever, respiratory distress including pneumonitis and pulmonary edema, anaphylactic reactions. Return to top

Special Senses(Hydrochlorothiazide)
Transient blurred vision, xanthopsia. Return to top

Metabolic(Hydrochlorothiazide)
Gout. Return to top

Genitourinary(Hydrochlorothiazide)
Sexual dysfunction, renal failure, renal dysfunction, interstitial nephritis. Return to top