Cinnamyl-alcohol dehydrogenase

In enzymology, a cinnamyl-alcohol dehydrogenase is an enzyme that catalyzes the chemical reaction


 * cinnamyl alcohol + NADP+ $$\rightleftharpoons$$ cinnamaldehyde + NADPH + H+

Thus, the two substrates of this enzyme are cinnamyl alcohol and NADP+, whereas its 3 products are cinnamaldehyde, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cinnamyl-alcohol:NADP+ oxidoreductase. Other names in common use include cinnamyl alcohol dehydrogenase, and CAD. This enzyme participates in phenylpropanoid biosynthesis.

Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes, , , and.