Salmeterol drug interactions

List of drug interactions
Monoamine oxidase inhibitors/tricyclic antidepressants Corticosteroids/cromoglycate Beta-adrenergic receptor blocking agents Nonpotassium-sparing diuretics Complete List of Drug Interactions

Monoamine oxidase inhibitors/tricyclic antidepressants
Salmeterol should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, because the action of salmeterol on the vascular system may be potentiated by these agents. Return to top

Corticosteroids/cromoglycate
In clinical trials, inhaled corticosteroids and/or inhaled cromolyn sodium did not alter the safety profile of salmeterol when administered concurrently. Return to top

Beta-adrenergic receptor blocking agents
Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as salmeterol, but may also produce severe bronchospasm in patients with asthma. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma. In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution. Return to top

Nonpotassium-sparing diuretics
The ECG changes and/or hypokalemia that may result from the administration of nonpotassium-sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. Although the clinical significance of these effects is not known, caution is advised in the coadministration of beta-agonists with nonpotassium-sparing diuretics. Return to top

Major Interactions

 * Agenerase
 * Akbeta
 * amprenavir
 * atazanavir
 * Betagan
 * Betagan C-Cap
 * Betapace
 * Betapace AF
 * Betapace AF(obsolete)
 * Betimol
 * Biaxin
 * Biaxin XL
 * Biaxin XL-Pak
 * Blocadren
 * carteolol
 * carteolol ophthalmic
 * Cartrol
 * carvedilol
 * carvedilol extended release
 * clarithromycin
 * clarithromycin extended release
 * conivaptan
 * Coreg
 * Coreg CR
 * Corgard
 * Crixivan
 * darunavir
 * delavirdine
 * Fortovase
 * fosamprenavir
 * Inderal
 * Inderal LA
 * indinavir
 * InnoPran XL
 * Invirase
 * Istalol
 * itraconazole
 * Ketek
 * Ketek Pak
 * ketoconazole
 * labetalol
 * Levatol
 * Levobunolol
 * levobunolol ophthalmic
 * Lexiva
 * metipranolol ophthalmic
 * miconazole
 * Monistat I.V.
 * nadolol
 * nefazodone
 * nelfinavir
 * Nizoral
 * Normodyne
 * Norvir
 * Norvir Soft Gelatin
 * Ocupress
 * OptiPranolol
 * penbutolol
 * pindolol
 * Prezista
 * propranolol
 * propranolol extended release
 * Rescriptor
 * Reyataz
 * ritonavir
 * saquinavir
 * saquinavir mesylate
 * Serzone
 * Sorine
 * sotalol
 * Sotalol Hydrochloride AF
 * Sotalol Hydrochloride AF(obsolete)
 * Sporanox
 * Tao
 * telithromycin
 * Telzir
 * timolol
 * timolol hemihydrate ophthalmic
 * timolol ophthalmic
 * timolol ophthalmic long-acting
 * Timoptic Ocudose
 * Timoptic Ocumeter
 * Timoptic Ocumeter Plus
 * Timoptic-XE
 * Trandate
 * troleandomycin
 * Vaprisol
 * Vfend
 * Viracept
 * Visken
 * voriconazole

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Moderate Interactions

 * abarelix
 * acetazolamide
 * acetazolamide extended release
 * Adapin
 * Adeno-jec
 * Adenocard
 * Adenoscan
 * adenosine
 * adenosine monophosphate
 * adenosine triphosphate
 * Adgan
 * Adriamycin
 * Adriamycin RDF
 * Aerolate III
 * Aerolate JR
 * Aerolate SR
 * alfuzosin
 * alfuzosin extended release
 * Aloxi
 * aminophylline
 * aminophylline extended release
 * amiodarone
 * amitriptyline
 * amoxapine
 * Anafranil
 * Anergan 50
 * Antinaus 50
 * Anzemet
 * APO-Go
 * APO-Go Pen
 * Apokyn
 * apomorphine
 * Aquaphyllin
 * Aquazide H
 * Aralen Hydrochloride
 * Aralen Phosphate
 * arsenic trioxide
 * Asendin
 * Asmalix
 * astemizole
 * Atapryl
 * atomoxetine
 * Avelox
 * Avelox I.V.
 * Aventyl HCl
 * Azilect
 * azithromycin
 * Azithromycin 3 Day Dose Pack
 * Azithromycin 5 Day Dose Pack
 * azithromycin extended release
 * bendroflumethiazide
 * benzthiazide
 * bepridil
 * Bronkodyl
 * bumetanide
 * Bumex
 * Carbex
 * Cardioquin
 * Carozide
 * Cerubidine
 * Chem Mart Tamoxifen
 * chloroquine
 * chloroquine hydrochloride
 * chloroquine phosphate
 * chlorothiazide
 * chlorpromazine
 * chlorpromazine extended release
 * chlorthalidone
 * Choledyl
 * Choledyl SA
 * Cipro
 * Cipro Cystitis Pack
 * Cipro I.V.
 * Cipro XR
 * ciprofloxacin
 * ciprofloxacin extended release
 * cisapride
 * Clomipramine
 * Compazine
 * Compazine Spansule
 * Compro
 * Cordarone
 * Cordarone I.V.
 * Corvert
 * dasatinib
 * Daunorubicin
 * Daunorubicin Liposomal
 * Daunoxome
 * Definity
 * Demadex
 * Demadex I.V.
 * desipramine
 * Diamox
 * Diamox Sequels
 * Diaqua
 * Diaqua-2
 * Dilor
 * Dilor-400
 * Diskets
 * disopyramide
 * disopyramide extended release
 * Diucardin
 * Diuril
 * Diuril Sodium
 * dofetilide
 * dolasetron
 * Dolophine
 * doxepin
 * doxepin topical
 * Doxil
 * Doxorubicin
 * Doxorubicin liposomal
 * droperidol
 * Dylix
 * dyphylline
 * E-Mycin
 * E.E.S. Granules
 * E.E.S.-200
 * E.E.S.-400
 * E.E.S.-400 Filmtab
 * Elavil
 * Eldepryl
 * Elixophyllin
 * Ellence
 * Emblon
 * Emsam
 * Endep
 * epirubicin
 * Ery-Tab
 * Eryc
 * EryPed
 * EryPed 200
 * EryPed 400
 * Erythrocin Lactobionate
 * Erythrocin Stearate Filmtab
 * Erythrocot
 * erythromycin
 * erythromycin base
 * erythromycin estolate
 * erythromycin ethylsuccinate
 * erythromycin lactobionate
 * erythromycin stearate
 * Esidrix
 * Eskalith
 * Eskalith-CR
 * Exna
 * EXUBERA
 * EXUBERA Combination Pack 12
 * EXUBERA Combination Pack 15
 * EXUBERA Kit
 * Ezide
 * Factive
 * FK506
 * flecainide
 * Floxin
 * Floxin I.V.
 * Fluothane
 * fluphenazine
 * fluphenazine decanoate
 * fluphenazine enanthate
 * fluphenazine hydrochloride
 * furazolidone
 * furosemide
 * Furoxone
 * gatifloxacin
 * gemifloxacin
 * Genox
 * GenRx Tamoxifen
 * Geodon
 * grepafloxacin
 * Haldol
 * Haldol Decanoate
 * Halfan
 * halofantrine
 * haloperidol
 * haloperidol decanoate
 * halothane
 * HCTZ
 * Hismanal
 * Hydro Par
 * hydrochlorothiazide
 * Hydrodiuril
 * hydroflumethiazide
 * Hygroton
 * ibutilide
 * Idamycin PFS
 * idarubicin
 * Ilosone
 * Ilotycin Gluceptate
 * imipramine
 * imipramine pamoate
 * Inapsine
 * indapamide
 * insulin inhalation rapid acting
 * Invega
 * isocarboxazid
 * Jumex
 * lapatinib
 * Largon
 * Lariam
 * Lasix
 * Levaquin
 * Levaquin Leva-Pak
 * Levitra
 * levofloxacin
 * levomethadyl acetate
 * Levoprome
 * linezolid
 * lithium
 * lithium carbonate
 * lithium carbonate extended release
 * lithium citrate
 * Lithobid
 * Lithonate
 * Lithotabs
 * Lo-Aqua
 * lomefloxacin
 * Loqua
 * Lorelco
 * Lozol
 * Ludiomil
 * Lufyllin
 * Lufyllin-400
 * mannitol
 * maprotiline
 * Marplan
 * Matulane
 * Maxaquin
 * mefloquine
 * Mellaril
 * Mellaril-S
 * mesoridazine
 * methadone
 * Methadose
 * methdilazine
 * methotrimeprazine
 * metolazone
 * Microzide
 * moxifloxacin
 * MY-E
 * My-O-Den
 * Mykrox
 * Nardil
 * Naturetin-10
 * Naturetin-5
 * Nebupent
 * Neothylline
 * nilotinib
 * Nolvadex
 * Nolvadex D
 * norfloxacin
 * Noroxin
 * Norpace
 * Norpace CR
 * Norpramin
 * nortriptyline
 * Noxafil
 * ofloxacin
 * ondansetron
 * Optison
 * Orap
 * Oretic
 * Orlaam
 * Ormazine
 * Osmitrol
 * oxtriphylline
 * oxtriphylline extended release
 * Pacerone
 * paliperidone
 * palonosetron
 * Pamelor
 * Parnate
 * PCE Dispertab
 * Pentam 300
 * pentamidine
 * Pentazine
 * perflutren
 * Permitil
 * perphenazine
 * Pharmorubicin PFS
 * Pharmorubicin RDF
 * Phenadoz
 * Phenazine 50
 * phenelzine
 * Phenergan
 * Phenergan Fortis
 * Phenoject-50
 * pimozide
 * Pitressin
 * Plenaxis
 * polythiazide
 * posaconazole
 * Pro-Med
 * probucol
 * procainamide
 * procainamide 12 hour extended release
 * procainamide extended release
 * Procan SR
 * Procanbid
 * procarbazine
 * prochlorperazine
 * prochlorperazine extended release
 * Procot
 * Prograf
 * Prolixin
 * Prolixin Decanoate
 * Prolixin Enanthate
 * Promacot
 * promazine
 * promethazine
 * Promethegan
 * Pronestyl
 * Pronestyl-SR
 * propafenone
 * propafenone extended release
 * propiomazine
 * Propulsid
 * Proquin XR
 * Prorex
 * protriptyline
 * Prudoxin
 * QM-260
 * Qualaquin
 * Quibron-T
 * Quibron-T/SR
 * Quin-G
 * Quin-Release
 * Quinaglute Dura-Tabs
 * Quinidex Extentabs
 * quinidine
 * quinidine extended release
 * quinine
 * Quinora
 * Ranexa
 * ranolazine
 * rasagiline
 * Raxar
 * Renese
 * Resectisol
 * Respbid
 * Risperdal
 * Risperdal Consta
 * Risperdal M-Tab
 * risperidone
 * Robimycin
 * Rythmol
 * Rythmol SR
 * Saluron
 * selegiline
 * Selgene
 * Serentil
 * Sinequan
 * Slo-Bid Gyrocaps
 * Slo-Phyllin
 * Slo-Phyllin 125
 * Slo-Phyllin 80
 * Soltamox
 * sparfloxacin
 * Sparine
 * Sprycel
 * Stelazine
 * Strattera
 * Surmontil
 * T-Phyl
 * Tacaryl
 * tacrolimus
 * Tambocor
 * Tamofen
 * Tamofen(obsolete)
 * Tamone
 * Tamosin
 * Tamoxen
 * tamoxifen
 * Tamoxifen Hexal
 * Tasigna
 * Temaril
 * Tequin
 * Tequin Teqpaq
 * terfenadine
 * Terry White Chemists Tamoxifen
 * Thalitone
 * Theo-24
 * Theo-Dur
 * Theo-Dur Sprinkles
 * Theo-Time
 * Theo-X
 * Theobid
 * TheoCap
 * Theochron
 * Theoclear L.A.-130
 * Theoclear L.A.-260
 * Theoclear-80
 * Theolair
 * Theolair-SR
 * theophylline
 * theophylline 24 hr extended release
 * theophylline extended release
 * Theovent
 * thiethylperazine
 * thioridazine
 * Thorazine
 * Tikosyn
 * tizanidine
 * Tofranil
 * Tofranil-PM
 * Torecan
 * torsemide
 * tranylcypromine
 * trifluoperazine
 * triflupromazine
 * Trilafon
 * trimeprazine
 * trimipramine
 * Trisenox
 * Truphylline
 * Truxophyllin
 * Tykerb
 * Uni-Dur
 * Uniphyl
 * Uprima
 * Uroxatral
 * V-Gan-25
 * V-Gan-50
 * Vanatrip
 * vardenafil
 * Vascor
 * vasopressin
 * Vivactil
 * vorinostat
 * Z-Pak
 * Zagam
 * Zagam Respipac
 * Zanaflex
 * Zaroxolyn
 * Zelapar
 * ziprasidone
 * Zithromax
 * Zithromax IV
 * Zithromax TRI-PAK
 * Zithromax Z-Pak
 * Zmax
 * Zofran
 * Zofran ODT
 * Zolinza
 * Zonalon
 * Zyvox

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