Isometheptene Mucate, Dichloralphenazone, and Acetaminophen

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Why this medication is prescribed
The combination of isometheptene mucate, dichloralphenazone, and acetaminophen is used to relieve migraine and tension headaches. It prevents blood vessels in your head from expanding and causing headaches.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How this medication should be used
The combination of isometheptene mucate, dichloralphenazone, and acetaminophen comes as a capsule to take by mouth. It usually is taken when a headache first begins and then as needed. Do not take more than five capsules in 12 hours or more than eight capsules per day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take isometheptene mucate, dichloralphenazone, and acetaminophen exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Special precautions
Before taking isometheptene mucate, dichloralphenazone, and acetaminophen,


 * tell your doctor and pharmacist if you are allergic to isometheptene mucate, dichloralphenazone, acetaminophen, or any other drugs.
 * tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antihistamines, MAO inhibitors [phenelzine (Nardil) and tranylcypromine (Parnate)], medications for depression such as chlorpromazine (Thorazine), sleeping pills, tranquilizers, and vitamins.
 * tell your doctor if you have or have ever had heart, kidney, or liver disease; glaucoma; high blood pressure; or artery disease.
 * tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking this medication, call your doctor.
 * you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
 * remember that alcohol can add to the drowsiness caused by this drug.

What to do if you forget a dose
This medication usually is taken as needed. If your doctor has told you to take isometheptene mucate, dichloralphenazone, and acetaminophen regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Minor side effects
Isometheptene mucate, dichloralphenazone, and acetaminophen may cause side effects. Tell your doctor if this symptom is severe or does not go away:


 * drowsiness

Severe side effects
If you experience the following symptom, call your doctor immediately:


 * skin rash

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

Storage conditions needed for this medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature, away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Other information
Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names

 * Iso-Acetazone®
 * Isocom®
 * Isopap®
 * Midchlor®
 * Midrin®
 * Migratine®
 * Mitride®