Hypermagnesaemia

Overview
Hypermagnesaemia occurs in patients with acute or chronic renal failure given antacids or laxatives containing magnesium. It can be induced by enemas containing magnesium.

Symptoms
Symptoms and signs include neurological and cardiovascular depression, weakness, respiratory paralysis and cardiac conduction defects.

Treatment
Treatment requires the cessation of any magnesium therapy. Calcium, insulin and dextrose may be given to counteract the plasma magnesium levels. Dialysis may be required in patients with severe renal failure.