Clarithromycin contraindications

List of contraindications
Hypersensitivity Drugs

Hypersensitivity
Clarithromycin is contraindicated in patients with a known hypersensitivity to Clarithromycin, erythromycin, or any of the macrolide antibiotics. Return to top

Drugs
Concomitant administration of Clarithromycin and any of the following drugs is contraindicated: cisapride, pimozide, astemizole, terfenadine, and ergotamine or dihydroergotamine. There have been post-marketing reports of drug interactions when Clarithromycin and/or erythromycin are co-administered with cisapride, pimozide, astemizole, or terfenadine resulting in cardiac arrhythmias (QT prolongation, ventricular tachycardia, ventricular fibrillation, and torsades de pointes) most likely due to inhibition of metabolism of these drugs by erythromycin and Clarithromycin. Fatalities have been reported. For information about contraindications of other drugs indicated in combination with Clarithromycin, refer to the Contraindications section of their package inserts. Return to top