Noncompaction cardiomyopathy biopsy

Overview
Both skeletal and cardiac biopsies may reveal abnormal histologic findings.

Skeletal Biopsy
A skeletal biopsy can be performed which may demonstrate inclusion bodies or myopathic changes.

Cardiac Biopsy

 * Interstitial fibrosis was observed in 5/5 patients with isolated noncompaction cardiomyopathy who underwent right ventricular biopsy
 * Endomyocardial thickening and subendocardial fibroelastosis was observed in 3/5 patients who underwent right ventricular biopsy.
 * Myocyte necrosis has been observed in areas of trabeculation.