TRNA isopentenyltransferase

In enzymology, a tRNA isopentenyltransferase is an enzyme that catalyzes the chemical reaction


 * isopentenyl diphosphate + tRNA $$\rightleftharpoons$$ diphosphate + tRNA containing 6-isopentenyladenosine

Thus, the two substrates of this enzyme are isopentenyl diphosphate and tRNA, whereas its two products are diphosphate and tRNA containing 6-isopentenyladenosine.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is isopentenyl-diphosphate:tRNA isopentenyltransferase. Other names in common use include transfer ribonucleate isopentenyltransferase, Delta2-isopentenyl pyrophosphate:tRNA-Delta2-isopentenyl, transferase, Delta2-isopentenyl pyrophosphate:transfer ribonucleic acid, and Delta2-isopentenyltransferase.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.