Pyrogallol hydroxytransferase

In enzymology, a pyrogallol hydroxytransferase is an enzyme that catalyzes the chemical reaction


 * 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene $$\rightleftharpoons$$ 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene

Thus, the two substrates of this enzyme are 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene, whereas its two products are 1,3,5-trihydroxybenzene and 1,2,3,5-tetrahydroxybenzene.

This enzyme belongs to the family of oxidoreductases. The systematic name of this enzyme class is 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase. Other names in common use include 1,2,3,5-tetrahydroxybenzene hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase, 1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase), pyrogallol hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase. This enzyme participates in benzoic acid degradation via CoA ligation.

Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes, , , , , and.