Alpha-4 beta-2 nicotinic receptor

Overview
The alpha-4 beta-2 nicotinic receptor ((α4)2(β2)3) is a type of nicotinic acetylcholine receptor, consisting of α4 and β2 subunits.

It is located in the brain, where activation yields post- and presynaptic excitation, mainly by increased Na+ and K+ permeability.

Agonists
Nicotinic agonists for this receptor include:
 * nicotine
 * epibatidine
 * acetylcholine
 * cytosine

Antagonists

 * mecamylamine
 * methylaconitine
 * α-conotoxin