Mycocerosate synthase

In enzymology, a mycocerosate synthase is an enzyme that catalyzes the chemical reaction


 * acyl-CoA + n methylmalonyl-CoA + 2n NADPH + 2n H+ $$\rightleftharpoons$$ multi-methyl-branched acyl-CoA + n CoA + n CO2 + 2n NADP+

The 4 substrates of this enzyme are acyl-CoA, methylmalonyl-CoA, NADPH, and H+, whereas its 4 products are multi-methyl-branched acyl-CoA, CoA, CO2, and NADP+.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing). This enzyme is also called mycocerosic acid synthase.