Chorismate mutase

In enzymology, a chorismate mutase is an enzyme that catalyzes the chemical reaction


 * chorismate $$\rightleftharpoons$$ prephenate

Hence, this enzyme has one substrate, chorismate, and one product, prephenate.

This enzyme belongs to the family of isomerases, specifically those intramolecular transferases transferring other groups. The systematic name of this enzyme class is chorismate pyruvatemutase. This enzyme is also called hydroxyphenylpyruvate synthase. This enzyme participates in phenylalanine, tyrosine and tryptophan biosynthesis.

Structural studies
As of late 2007, 24 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , , , , , , , , , , , , , and.