3'(2'),5'-bisphosphate nucleotidase

In enzymology, a 3'(2'),5'-bisphosphate nucleotidase is an enzyme that catalyzes the chemical reaction


 * adenosine 3',5'-bisphosphate + H2O $$\rightleftharpoons$$ adenosine 5'-phosphate + phosphate

Thus, the two substrates of this enzyme are adenosine 3',5'-bisphosphate and H2O, whereas its two products are adenosine 5'-phosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase. Other names in common use include phosphoadenylate 3'-nucleotidase, 3'-phosphoadenylylsulfate 3'-phosphatase, phosphoadenylate 3'-nucleotidase, and 3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase. This enzyme participates in sulfur metabolism.

Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes, , , , , and.