Gonadoblastoma pathophysiology

Pathophysiology
Gonadoblastoma is most often associated with abnormal chromosomal karyotype, gonadal dysgenesis, and the presence of a Y chromosome.

It has been found in association with Turner's syndrome.

Gonadoblastoma is classified as a germ cell tumor.

Formerly, gonadoblastoma was sometimes regarded as a subset of dysgerminoma. In modern literature, it is sometimes considered to progress to dysgerminoma.