Alpha,alpha-trehalase

In enzymology, an alpha,alpha-trehalase is an enzyme that catalyzes the chemical reaction


 * alpha,alpha-trehalose + H2O $$\rightleftharpoons$$ 2 D-glucose

Thus, the two substrates of this enzyme are alpha,alpha-trehalose and H2O, whereas its product is D-glucose.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha,alpha-trehalose glucohydrolase. This enzyme is also called trehalase. This enzyme participates in starch and sucrose metabolism.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.