HLA-A32

HLA-A32 (A32) is an HLA-A serotype. The serotype identifies the more common HLA-A*32 gene products. A32 is a split antigen of the A19 serotype group. This group also includes A29, A30, A31, A33, and A74 serotypes

Serotype
Serotyping efficiency for the predominant allele is good. There are 16 known alleles that result in 15 isoforms of HLA-A32. One isoform may be poorly expressed.

HLA-A*3201 allele frequencies
A32 is most common around the Persion Gulf and the Mediterranean Basin. It has a consistent presence in Europe. The A32 frequenceies in the more isolated (genetically) peoples of Europe suggests that the A32 rise in the mediterranean may only be partially attributable to recent migrations from the middle eastern region. There is a node in southern europe around the Ionian Sea in which specific, European, A32-haplotypes are elevated.

A32 Haplotypes
A common A32 haplotype A*3201-B*5101 can be found in Oman, United Arab Emirates, SE Iran, Bulgaria, and Portugal. A second, A*3201-B*3501 can be in the Omani, UAE, and Portugal.