TRPC5

Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is subtype of the TRPC family of mammalian transient receptor potential ion channels. Homomultimeric TRP5 and heteromultimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin . This activation probably plays a role in rheumatoid arthritis.