Zocor contraindications

List of contraindications
Hypersensitivity Active liver disease Pregnancy and lactation

Hypersensitivity
Zocor is contradicted in patients whom are hypersensitivity to any component of this medication. Return to top

Active liver disease
Zocor is contradicted in patients whom posses active liver disease or unexplained persistent elevations of serum transaminases. Return to top

Pregnancy and lactation
Atherosclerosis is a chronic process and the discontinuation of lipid-lowering drugs during pregnancy should have little impact on the outcome of long-term therapy of primary hypercholesterolemia. Moreover, cholesterol and other products of the cholesterol biosynthesis pathway are essential components for fetal development, including synthesis of steroids and cell membranes. Because of the ability of inhibitors of HMG-CoA reductase such as ZOCOR to decrease the synthesis of cholesterol and possibly other products of the cholesterol biosynthesis pathway, ZOCOR is contraindicated during pregnancy and in nursing mothers. ZOCOR should be administered to women of childbearing age only when such patients are highly unlikely to conceive. If the patient becomes pregnant while taking this drug, ZOCOR should be discontinued immediately and the patient should be apprised of the potential hazard to the fetus. Return to top