Orlistat instructions for administration

Instructions for administration
Recommended dose Nutritional Balance Effects with Xenical above 120mg

Recommended dose
The recommended dose of XENICAL is one 120- mg capsule three times a day with each main meal containing fat (during or up to 1 hour after the meal). Return to top

Nutritional Balance
The patient should be on a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat. The daily intake of fat, carbohydrate, and protein should be distributed over three main meals. If a meal is occasionally missed or contains no fat, the dose of XENICAL can be omitted. Because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene, patients should be counseled to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition. The supplement should be taken at least 2 hours before or after the administration of XENICAL, such as at bedtime. Return to top

Effects with Xenical above 120mg
Doses above 120 mg three times a day have not been shown to provide additional benefit. Based on fecal fat measurements, the effect of XENICAL is seen as soon as 24 to 48 hours after dosing. Upon discontinuation of therapy, fecal fat content usually returns to pretreatment levels within 48 to 72 hours. Return to top