Zadik Barak Levin syndrome

Zadik Barak Levin Syndrome (ZBLS) is a congenital disorder in humans. Presenting conditions include primary hypothyroidism, cleft palate, hypodontia, and ectodermal dysplasia. It is the result of an embryonic defect in the mesodermal-ectodermal midline development.

Frequent signs

 * anodontia/oligodontia &mdash; no teeth or fewer teeth than normal
 * cleft palate
 * depressed nasal bridge
 * dry skin
 * ectopic/agenesis/hypoplastic thyroid
 * epibulbar dermoid
 * frontal bossing
 * hypertelorism
 * hypothyroidism
 * lordosis
 * macroglossia
 * microcephaly
 * micrognatia/retrognatia &mdash; small or recessed jaw(s)
 * polyhydramnios
 * short stature/dwarfism
 * sparse/absent scalp hair(generalized)
 * squint/paresis of ocular muscles
 * umbilical hernia