Lobeline

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Lobeline is a molecule which binds VMAT2. It is a natural alkaloid found in "Indian tobacco" (Lobelia inflata), "Devil's tobacco" (Lobelia tupa), and Hippobroma Longiflora.

Lobeline has been used as a smoking cessation aid, despite no conclusive evidence of effectiveness.

It is a nicotinic agonist.Dr.Linda Dwoskin, college of pharmacy, University of kentucky has done a commnedable work on lobeline.