The Living Guidelines: UA/NSTEMI Recommendations for Non steroidal Anti-Inflammatory Drugs Use Suggest Revisions to the CLASS III Guidelines

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Class III Guidelines

 * 1) Non steroidal anti inflammatory drugs with increasing degrees of relative COX-2 selectivity should not be administered to UA / NSTEMI patients with chronic musculoskeletal discomfort when therapy with acetaminophen, small doses of narcotics, non acetylated salicylates, or non selective NSAIDs provides acceptable levels of pain relief. (Level of Evidence: C)