Sodium-hydrogen antiporter 3

Sodium-hydrogen antiporter 3 or Sodium-hydrogen exchanger 3 (NHE3) is an isoform of sodium-hydrogen antiporters. It is found in the nephron of the kidney and is primarily responsible for maintaining the balance of sodium.

Regulation
Protein kinase C stimulates NHE3, while protein kinase A inhibits it.

There is a specific protein functioning as an NHE3 regulator, sodium-hydrogen antiporter 3 regulator 1.

Classification
It is a solute carrier family 9 (sodium/hydrogen exchanger), member 3

Gene
It is encoded by the gene SLC9A3.