Pseudoviridae

Pseudovirus Hemivirus

The Pseudoviridae are a family of viruses, including the following genera:
 * Genus Pseudovirus; type species: Saccharomyces cerevisiae Ty1 virus
 * Genus Hemivirus; type species: Drosophila melanogaster copia virus

The type species Saccharomyces cerevisiae Ty1 virus, from the genus pseudovirus and the type species Drosophila melanogaster copia virus from the genus Hemivirus, both belong to the Pseudoviridae family. The Hemivirus and Pseudovirus constitute the two genera of Pseudoviridae.

Pseudoviridae is classified under group VI RNA Reverse Transcribing Viruses and infect fungal, or invertebrate. The genome of viruses from this family is unsegmented, -RT, positive-sense, single-stranded RNA and is 4200-9700 nucleotides long. The genome encodes structural proteins and non-structural proteins which codes for an RNA-dependent DNA polymerase, replicase, and reverse transcriptase for the reverse transcription step during replication.

Its genome integrates into the host genome and gets transcribed by host cell enzymes such as eukaryotic nuclear RNA polymerase II. Genome replication takes place in the host cytoplasm, or the nucleus and assembly can occur in the cytoplasm, or in the nucleus.The viral capsid is unenveloped and looks roughly spherical. The capsid is round with icosahedral symmetry (T=3 and 4), and is also isometric to quasi-isometric and has a diameter of 30-50 nm. LTR- retrotransposons are poorly characterized and lipids are not reported Pseudoviridae comprises highly divergent members and most Pseudoviridae encode Gag and Pol on a single open reading frame.