3-dehydroquinate dehydratase

In enzymology, a 3-dehydroquinate dehydratase is an enzyme that catalyzes the chemical reaction


 * 3-dehydroquinate $$\rightleftharpoons$$ 3-dehydroshikimate + H2O

Hence, this enzyme has one substrate, 3-dehydroquinate, and two products, 3-dehydroshikimate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming). Other names in common use include 3-dehydroquinate hydrolase, DHQase, dehydroquinate dehydratase, 3-dehydroquinase, 5-dehydroquinase, dehydroquinase, 5-dehydroquinate dehydratase, 5-dehydroquinate hydro-lyase, and 3-dehydroquinate hydro-lyase. This enzyme participates in phenylalanine, tyrosine and tryptophan biosynthesis.

Structural studies
As of late 2007, 26 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , , , , , , , , , , , , , , , and.