Strombine dehydrogenase

In enzymology, a strombine dehydrogenase is an enzyme that catalyzes the chemical reaction


 * N-(carboxymethyl)-D-alanine + NAD+ + H2O $$\rightleftharpoons$$ glycine + pyruvate + NADH + H+

The 3 substrates of this enzyme are N-(carboxymethyl)-D-alanine, NAD+, and H2O, whereas its 4 products are glycine, pyruvate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming). Other names in common use include strombine[N-(carboxymethyl)-D-alanine]dehydrogenase, and N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase.