Scytalone dehydratase

In enzymology, a scytalone dehydratase is an enzyme that catalyzes the chemical reaction


 * scytalone $$\rightleftharpoons$$ 1,3,8-trihydroxynaphthalene + H2O

Hence, this enzyme has one substrate, scytalone, and two products, 1,3,8-trihydroxynaphthalene and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming). This enzyme is also called scytalone 7,8-hydro-lyase.

Structural studies
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , and.