Phenazone

Overview
Phenazone, or phenazon, is an analgesic. It is formed by reducing diortho-dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 C. It crystallizes in needles which melt at 156 C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid.

Synonyms
Analgesine, Antipyrine, Diméthyloxyquinazine, Oxydiméthylquinazine, Oxydiméthylquinizine, Pyrazoline

Chimic Class

 * Pyrazole
 * Pyrazolinone

Pharmacology

 * Analgesics
 * Antipyretic
 * NSAID

Adverse effects

 * Allergy to pyrazolones
 * Nausea
 * Agranulocytosis

Phénazone アンチピリン Антипирин Antipyriini

Antypiryna Antipirin