Enalapril overdose

Limited data are available in regard to overdosage in humans.

Single oral doses of Enalapril above 1,000 mg/kg and >1,775 mg/kg were associated with lethality in mice and rats, respectively.

The most likely manifestation of overdosage would be hypotension, for which the usual treatment would be intravenous infusion of normal saline solution. Enalaprilat may be removed from general circulation by hemodialysis and has been removed from neonatal circulation by peritoneal dialysis.