Microstomia

Overview
Microstomia (micro- a combining form meaning small + -stomia a combining form meaning mouth = (abnormally) "small mouth") is a clinical feature of many craniofacial syndromes, including Freeman-Sheldon syndrome and Sheldon-Hall syndromes (or distal arthrogryposis multiplex congenita). It may present with whistling-face feature, as well, as in Freeman-Sheldon syndrome. In this syndrome, it impairs alimentation and may require oral commissurotomies, with subsequent revisions, to improve function.

Congenital conditions

 * Fine-Lubinsky syndrome
 * Fryns-van den Berghe syndrome
 * Hallermann-Streiff syndrome (HSS)

Chromosomal abnormalities

 * Velocardiofacial syndrome

Autosomal dominant conditions

 * Amyotrophy, hereditary neuralgic
 * Freeman-Sheldon syndrome
 * Micrognathia with peromelia
 * Velocardiofacial syndrome

Autosomal recessive conditions

 * Burton syndrome
 * Epidermolysis bullosa dystrophica, Hallopeau-Siemens type
 * Fibrochondrogenesis
 * Hennekam syndrome
 * Schwartz-Jampel-Aberfeld syndrome

Mikrostomia