Immunoproteomics

Immunoproteomics is a term used to describe the study of large sets of proteins (proteomics) involved in the immune response. Examples of common applications of immunoproteomics include; 1) the isolation and mass spectrometric identification of MHC (major histocompatibility complex) binding peptides 2) purification and identification of protein antigens binding specific antibodies (or other affinity reagents) 3) Comparative immunoproteomics to identify proteins and pathways modulated by a specific infectious organism, disease or toxin. The term proteomics also usually implies that mass spectrometry is the ultimate technique used for protein identification.