Ganglion type nicotinic receptor

The ganglion type nicotinic receptor is a type of nicotinic acetylcholine receptor, consisting of the subunit combination (α1)2(β4)3.

It is located in the autonomic ganglia, where activation yields EPSP, mainly by increased Na+ and K+ permeability.

Agonists
Nicotinic agonists for this receptor include:
 * acetylcholine
 * carbachol
 * nicotine
 * epibatidine
 * dimethylphenylpiperazinium

Antagonists

 * α-bungarotoxin
 * mecamylamine
 * trimetaphan