3,4-Dimethylamphetamine

3,4-dimethylamphetamine (Xylopropamine, α,3,4-trimethylphenethylamine) is a stimulant drug derived from amphetamine which was invented in the 1950s.

Xylopropamine was developed as an appetite suppressant in the 1950s and briefly sold as the sulphate salt, but it was not widely marketed. Other related amphetamine derivatives such as 2,4-dimethylamphetamine were also investigated for the same purpose, however these drugs had negative side effects such as high blood pressure and were not very successful, mainly due to the introduction of alternative drugs such as phentermine which had similar efficacy but less side effects.

Xylopropamine was also reported as having analgesic and anti-inflammatory effects but its side effects profile meant that it was never further developed for these applications.