Retinal dehydrogenase

In enzymology, a retinal dehydrogenase is an enzyme that catalyzes the chemical reaction


 * retinal + NAD+ + H2O $$\rightleftharpoons$$ retinoate + NADH + 2 H+

The 3 substrates of this enzyme are retinal, NAD+, and H2O, whereas its 3 products are retinoate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is retinal:NAD+ oxidoreductase. This enzyme is also called cytosolic retinal dehydrogenase. This enzyme participates in retinol metabolism. It has 2 cofactors: FAD, and Metal.