1,2,4-Triazole

1,2,4-Triazole is one of a pair of isomeric chemical compounds with molecular formula C2H3N3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,4-Triazole is a basic aromatic heterocycle.

1,2,4-Triazoles can be prepared synthetically using the Einhorn-Brunner reaction in which an imide is reacted with an alkyl hydrazine to form a mixture of isomeric 1,2,4-triazoles.

1,2,4-Triazole derivatives find use in a wide variety of applications, most notably as antifungals such as fluconazole and itraconazole.