Aase-Smith

Aase-Smith syndrome is characterized by the presence of three phlangeal bones (thumb), instead of the normal two. It is normally detected in infancy. Along with the abnormal bone growth, there is also a marked reduction in the ability to produce red blood cells (anemia), which help fight infection. This puts people with Aase-Smith syndrome at risk to become very ill, very easily. The syndrome is named for the American dysmorphologists Jon Aase and David W. Smith. Alternative names for the syndrome include:

Anemia and triphalangeal thumbs Congenital anemia and triphalangeal thumbs Hypoplastic anemia-triphalangeal thumbs, Aase-Smith type.