RNA uridylyltransferase

In enzymology, a RNA uridylyltransferase is an enzyme that catalyzes the chemical reaction


 * UTP + RNAn $$\rightleftharpoons$$ diphosphate + RNAn+1

Thus, the two substrates of this enzyme are UTP and RNAn, whereas its two products are diphosphate and RNAn+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:RNA uridylyltransferase. Other names in common use include terminal uridylyltransferase, and TUT.

Structural studies
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , and.