Bruton disease

Bruton disease or Bruton agammaglobulinemia is a hereditary type of agammaglobulinemia that is a sex-linked recessive disorder characterized by a deficiency of all types of immunoglobulins, reflecting a failure of the entire humoral antibody marrow system; the thymus may be normal, but the lymph nodes and spleen lack lymph cell follicles.

Differential diagnosis

 * Acrodermatitis enteropathica
 * Ataxia telangiectasia
 * Atopic dermatitis
 * Avitaminosis A
 * Common Variable Immunodeficiency
 * Severe Combined Immunodeficiency

[[Category:Immunology]