Blaise ketone synthesis

The Blaise ketone synthesis is the chemical reaction of acid chlorides with organozinc compounds to give ketones.



The reaction also works with organocuprates.

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Blaise-Maire reaction
The Blaise-Maire reaction is the Blaise ketone synthesis using β-hydroxy acid chlorides to give β-hydroxyketones, which are converted into α,β-unsaturated ketones using sulfuric acid.