The Living Guidelines: UA/NSTEMI Anticoagulant Therapy Polling Results for CLASS I Guidelines

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Class I Guidelines
Anticoagulant therapy should be added to antiplatelet therapy in UA/NSTEMI patients as soon as possible after presentation.

a. For patients in whom an invasive strategy is selected, regimens with established efficacy at a Level of Evidence: A include enoxaparin and UFH, and those with established efficacy at a Level of Evidence: B include bivalirudin and fondaparinux.

 Anticoagulant Therapy CLASS I Recommendation 1a should be: CLASS I CLASS IIa CLASS IIb CLASS III

b. For patients in whom a conservative strategy is selected, regimens using either enoxaparin or UFH (Level of Evidence: A) or fondaparinux (Level of Evidence: B) have established efficacy.

 Anticoagulant Therapy CLASS I Recommendation 1b should be: CLASS I CLASS IIa CLASS IIb CLASS III

c. In patients in whom a conservative strategy is selected and who have an increased risk of bleeding, fondaparinux is preferable. (Level of Evidence: B)

 Anticoagulant Therapy CLASS I Recommendation 1c should be: CLASS I CLASS IIa CLASS IIb CLASS III