Mir-8/mir-141/mir-200 microRNA precursor family

The miR-8 microRNA precursor (homologous to miR-141, miR-200), is a short non-coding RNA gene involved in gene regulation. miR-8 from Drosophila (MI0000128) and human and mouse mir-141 (MI0000166, MI0000457), mir-429 (MI0001642) and mir-200 (MI0000243, MI0000342) are expressed from the 3' arm of related precursor hairpins (represented here). Members of this precursor family have now been predicted or experimentally confirmed in a wide range of species (MIPF0000019). The bounds of the precursors are predicted based on conservation and base pairing and are not generally known.

Targets of miR-8
The atrophin gene has been shown to be a target of drosophila miR-8. It has also been suggested that this target is also conserved in mammalian miR-8.

The human miR-200c is likely to target the zinc finger transcription factor transcription factor 8 (TCF8) gene.