Estradiol side effects

List of Side Effects
Genitourinary system Breasts Cardiovascular Gastrointestinal Skin Eyes Central nervous system Miscellaneous

Genitourinary system

 * Changes in vaginal bleeding pattern and abnormal withdrawal bleeding or flow; breakthrough bleeding, spotting, dysmenorrhea
 * Increase in size of uterine leiomyomata
 * Vaginitis, including vaginal candidiasis
 * Change in amount of cervical secretion
 * Changes in cervical ectropion
 * Ovarian cancer; endometrial hyperplasia; endometrial cancer Return to top

Breasts
Tenderness, enlargement, pain, nipple discharge, galactorrhea; fibrocystic breast changes; breast cancer. Return to top

Cardiovascular
Deep and superficial venous thrombosis; pulmonary embolism; thrombophlebitis; myocardial infarction; stroke; increase in blood pressure. Return to top

Gastrointestinal

 * Nausea, vomiting
 * Abdominal cramps, bloating
 * Cholestatic jaundice
 * Increased incidence of gallbladder disease
 * Pancreatitis
 * Enlargement of hepatic hemangiomas. Return to top

Skin

 * Chloasma or melasma that may persist when drug is discontinued
 * Erythema multiforme
 * Erythema nodosum
 * Hemorrhagic eruption
 * Loss of scalp hair
 * Hirsutism
 * Pruritus, rash. Return to top

Eyes

 * Retinal vascular thrombosis
 * Steepening of corneal curvature
 * Intolerance to contact lenses. Return to top

Central nervous system

 * Headache, migraine, dizziness
 * Mental depression
 * Chorea
 * Nervousness, mood disturbances, irritability
 * Exacerbation of epilepsy
 * Dementia. Return to top

Miscellaneous

 * Increase or decrease in weight
 * Reduced carbohydrate tolerance
 * Aggravation of porphyria
 * Edema
 * Arthralgias; leg cramps
 * Changes in libido
 * Urticaria
 * Angioedema
 * Anaphylactoid/anaphylactic reactions
 * Hypocalcemia
 * Exacerbation of asthma
 * Increased triglycerides. Return to top