Abietadiene synthase

In enzymology, an abietadiene synthase is an enzyme that catalyzes the chemical reaction


 * (+)-copalyl diphosphate $$\rightleftharpoons$$ (-)-abietadiene + diphosphate

Hence, this enzyme has one substrate, (+)-copalyl diphosphate, and two products, (-)-abietadiene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is (+)-copalyl-diphosphate diphosphate-lyase [cyclizing (-)-abietadiene-forming]. This enzyme is also called copalyl-diphosphate diphosphate-lyase (cyclizing). This enzyme participates in diterpenoid biosynthesis.