5-HT6 receptor

The 5-HT6 receptor, also known as the 5-hydroxytryptamine (serotonin) receptor 6 (HTR6), is a human gene. The 5-HT6 receptor is primarily expressed in the brain and is involved in glutamatergic and cholinergic neuronal activity. It is a potential target for drugs treating cognitive diseases, schizophrenia, anxiety and obesity.

Full agonists
Agonists for the 5-HT6 receptor include:
 * 2-ethyl-5-methoxy-N,N-dimethyltryptamine (EMDT)
 * arylsulfonyl-tryptamines
 * arylsulfonyl-heterocycles.