Glycerol dehydrogenase

In enzymology, a glycerol dehydrogenase is an enzyme that catalyzes the chemical reaction


 * glycerol + NAD+ $$\rightleftharpoons$$ glycerone + NADH + H+

Thus, the two substrates of this enzyme are glycerol and NAD+, whereas its 3 products are glycerone, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycerol:NAD+ 2-oxidoreductase. Other names in common use include glycerin dehydrogenase, and NAD+-linked glycerol dehydrogenase. This enzyme participates in glycerolipid metabolism.

Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes, , , and.