Vinylacetyl-CoA Delta-isomerase

In enzymology, a vinylacetyl-CoA Delta-isomerase is an enzyme that catalyzes the chemical reaction


 * vinylacetyl-CoA $$\rightleftharpoons$$ crotonyl-CoA

Hence, this enzyme has one substrate, vinylacetyl-CoA, and one product, crotonyl-CoA.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is vinylacetyl-CoA Delta3-Delta2-isomerase. Other names in common use include vinylacetyl coenzyme A Delta-isomerase, vinylacetyl coenzyme A isomerase, and Delta3-cis-Delta2-trans-enoyl-CoA isomerase. This enzyme participates in butanoate metabolism.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.