FOLFIRI

Overview
FOLFIRI is a chemotherapy regimen for treatment of colorectal cancer, made up of the drugs


 * FOL – folinic acid (leucovorin)
 * F –  fluorouracil (5-FU)
 * IRI – irinotecan (Camptosar)

The regimen consists of:
 * Irinotecan (180 mg/m² IV over 90 minutes) concurrently with folinic acid (400 mg/m² [or 2 x 250 mg/m²] IV over 120 minutes).


 * Followed by fluorouracil (400-500 mg/m² IV bolus) then fluorouracil (2400-3000mg/m² intravenous infusion over 46 hours).

This cycle is typically repeated every two weeks.

The dosages shown above may vary from cycle to cycle.