N-succinylarginine dihydrolase

In enzymology, a N-succinylarginine dihydrolase is an enzyme that catalyzes the chemical reaction


 * N2-succinyl-L-arginine + 2 H2O $$\rightleftharpoons$$ N2-succinyl-L-ornithine + 2 NH3 + CO2

Thus, the two substrates of this enzyme are N2-succinyl-L-arginine and H2O, whereas its 3 products are N2-succinyl-L-ornithine, NH3, and CO2.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N2-succinyl-L-arginine iminohydrolase (decarboxylating). Other names in common use include N2-succinylarginine dihydrolase, arginine succinylhydrolase, SADH, AruB, AstB, and 2-N-succinyl-L-arginine iminohydrolase (decarboxylating). This enzyme participates in arginine and proline metabolism.