Cellobiose dehydrogenase (acceptor)

In enzymology, a cellobiose dehydrogenase (acceptor) is an enzyme that catalyzes the chemical reaction


 * cellobiose + acceptor $$\rightleftharpoons$$ cellobiono-1,5-lactone + reduced acceptor

Thus, the two substrates of this enzyme are cellobiose and acceptor, whereas its two products are cellobiono-1,5-lactone and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is cellobiose:acceptor 1-oxidoreductase. Other names in common use include cellobiose dehydrogenase, cellobiose oxidoreductase, Phanerochaete chrysosporium cellobiose oxidoreductase, CBOR, cellobiose oxidase, cellobiose:oxygen 1-oxidoreductase, CDH, and cellobiose:(acceptor) 1-oxidoreductase. It employs one cofactor, FAD.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.