Miotine

Miotine is an anticholinesteras drug. Miotine was the first synthetic carbamate that was used clinically.

Unlike miotine's analouge neostigmine it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can therefore form it's unpolar free base which could allow it to cross the blood-brain barrier and cause unwanted central nervous system (CNS) side effects.