Iodoacetate



The iodoacetate anion is an alkylating agent which acts on cysteine residues in proteins. It is often used to modify SH-groups to prevent the re-formation of disulfide bonds after the reduction of cystine residues to cysteine during protein sequencing.

The protonated form of iodoacetate is often called monoiodoacetic acid or simply iodoacetic acid.