Penicillin VK instructions for administration

Instructions for administration
Overview Streptococcal infections Pneumococcal infections Staphylococcal infections Fusospirochetosis Rheumatic fever/chorea Prophylaxis against bacterial endocarditis

Overview
The dosage of penicillin V should be determined according to the sensitivity of the causative microorganisms and the severity of infection, and adjusted to the clinical response of the patient. Return to top

Streptococcal infections
Streptococcal infections - mild to moderately severe - of the upper respiratory tract and including scarlet fever and erysipelas: 125 to 250 mg (200,000 to 400,000 units) every 6 to 8 hours for 10 days (dosage recommendations for adults and children 12 years and over). Return to top

Pneumococcal infections
Pneumococcal infections - mild to moderately severe - of the respiratory tract, including otitis media: 250 to 500 mg (400,000 to 800,000 units) every 6 hours until the patient has been afebrile for at least 2 days (dosage recommendations for adults and children 12 years and over). Return to top

Staphylococcal infections
Staphylococcal infections - mild infections of skin and soft tissue (culture and sensitive tests should be performed): 250 to 500 mg (400,000 to 800,000 units) every 6 to 8 hours (dosage recommendations for adults and children 12 years and over). Return to top

Fusospirochetosis
Fusospirochetosis (Vincent 's infection) of the oropharynx. Mild to moderately severe infections: 250 to 500 mg (400,000 to 800,000 units) every 6 to 8 hours (dosage recommendations for adults and children 12 years and over). Return to top

Rheumatic fever/chorea
For the prevention of recurrence following rheumatic fever and/or chorea: 125 to 250 mg (200,000 to 400,000 units) twice daily on a continuing basis (dosage recommendations for adults and children 12 years and over). Return to top

Prophylaxis against bacterial endocarditis
For prophylaxis against bacterial endocarditis1 in patients with congenital heart disease or rheumatic or other acquired valvular heart disease when undergoing dental procedures or surgical procedures of the upper respiratory tract: 2 gram of penicillin V (1.0 gram for children under 60 lbs.) 1 hour before the procedure, and then, 1 gram (500 mg for children under 60 lbs.) 6 hours later (dosage recommendations for adults and children 12 years and over). Return to top