Peroxisomal disorder

Peroxisomal disorders are a class of conditions which lead to disorders of lipid metabolism.

Zellweger syndrome
A deficiency in the protein import can lead to empty peroxisomes, leading to abnormalities in the brain, called Zellweger syndrome. A deficiency in the peroxin Pex2 has shown to be responsible for one form of the syndrome. A milder inherited disease is caused by a defective receptor for the N-terminal import signal. Deficiency of the formation of plasmalogens can also cause severe brain disorders, leading to neurological disease.

Other peroxisomal disorders
Other examples of peroxisomal disorders include:
 * Acatalasia
 * Adrenoleukodystrophy
 * Refsum's disease
 * Rhizomelic chondrodysplasia punctata