Proventil HFA side effects

List of side effects
Common adverse effects Paradoxical Bronchospasm Deterioration of Asthma Use of Anti-inflammatory Agents Cardiovascular Effects Immediate Hypersensitivity Reactions

Common adverse effects
Common adverse effects of treatment with Proventil HFA Inhalation Aerosol include palpitations, chest pain, rapid heart rate, tremor, or nervousness. Effective and safe use of Proventil HFA Inhalation Aerosol includes an understanding of the way that it should be administered. Use Proventil HFA Inhalation Aerosol only with the yellow actuator supplied with the product. The Proventil HFA Inhalation Aerosol actuator should not be used with other aerosol medications. Return to top

Paradoxical Bronchospasm
Inhaled albuterol sulfate can produce paradoxical bronchospasm that may be life threatening. If paradoxical bronchospasm occur, Proventil HFA Inhalation Aerosol should be discontinued immediately and alternative therapy instituted. It should be recognized that paradoxical bronchospasm, when associated with inhaled formulations, frequently occurs with the first use of a new canister. Return to top

Deterioration of Asthma
Asthma may deteriorate acutely over a period of hours or chronically over several days or longer. If the patient needs more doses of Proventil HFA Inhalation Aerosol than usual, this may be a marker of destabilization of asthma and requires re-evaluation of the patient and treatment regimen, giving special consideration to the possible need for anti-inflammatory treatment, eg, corticosteroids. Return to top

Use of Anti-inflammatory Agents
The use of beta-adrenergic-agonist bronchodilators alone may not be adequate to control asthma in many patients. Early consideration should be given to adding anti-inflammatory agents, eg, corticosteroids, to the therapeutic regimen. Return to top

Cardiovascular Effects
Proventil HFA Inhalation Aerosol, like other beta-adrenergic agonist, can produce clinically significant cardiovascular effects in some patients as measured by pulse rate, blood pressure, and/or symptoms. Although such effects are uncommon after administration of Proventil HFA Inhalation Aerosol at recommended doses, if they occur, the drug may need to be discontinued. In addition, beta agonists have been reported to produce ECG changes, such as flattening of the T wave, prolongation of the QTc interval, and ST segment depression. The clinical significance of these findings is unknown. Therefore, Proventil HFA Inhalation Aerosol, like all sympathomimetic amines, should be used with caution in patients with cardiovascular disorders, especially coronary insufficiency, cardiac arrhythmias, and hypertension. Return to top

Immediate Hypersensitivity Reactions
Immediate hypersensitivity reactions may occur after administration of albuterol sulfate, as demonstrated by rare cases of urticaria, angioedema, rash, bronchospasm, anaphylaxis, and oropharyngeal edema. Return to top