Hyperthyroidism (patient information)

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Overview
Hyperthyroidism is a disorder that the thyroid gland makes too much thyroid hormone. About 1 percent of the U.S. population has hyperthyroidism. Some diseases, such as Graves’ disease, thyroid nodules and thyroiditis, are associated with the cause of hyperthyroidism. Hyperthyroidism can affect your metabolism. Usual signs and symptoms include goiter, increased appetite but weight loss, palpitation, hypertension, increased sensitivity to heat and perspiration, nervousness and hand tremors. Thyroid-Stimulating Hormone (TSH) test is a very sensitive and useful test to indentify the disorder. Other examinations include T3 and T4 test, radioactive iodine uptake test and thyroid scan. Treatment opinion of hyperthyroidism depends on the cause, age, physical condition and the severity of symptoms. Usual treatment measures are medications, redioactive iodine and thyroidectomy. The common side effect of redioactive iodine and thyroidectomy is hypothyroidism. If happens, the patient needs to take thyroid hormone supplement to restore normal hormone levels.

What are the symptoms of hyperthyroidism?
Symptoms of hyperthyroidism vary from person to person. Usual sings include the following:
 * Goiter
 * Increased appetite, but weight loss
 * Palpitation
 * Hypertension
 * Increased sensitivity to heat and perspiration
 * Nervousness, anxiety or irritability, difficulty sleeping
 * Hand tremors
 * Fatigue, muscle weakness
 * Changes in menstrual patterns (usually lighter flow, less frequent periods) in women

Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.

Who is at highest risk?

 * Graves’ disease
 * Thyroid nodules
 * Thyroiditis
 * Too much of iodine ingestion
 * Overmedicating with synthetic thyroid hormone

Diagnosis

 * Thyroid-Stimulating Hormone (TSH) test: This is a very sensitive and useful test and usually used as the first test to identify the disorder. The TSH test is based on the feedback between TSH and thyroid hormone. Patients with hyperthyroidism may show a lower reading than normal people.
 * T3 and T4 test: This test may show the levels of T3 and T4 in your blood. In patients with hyperthyroidism, the levels of one or both of these hormones in your blood will be higher than normal.
 * Thyroid-stimulating immunoglobulin (TSI) test: This test may help diagnose Grave's disease, which has this kind of antibody.
 * Radioactive iodine uptake test: This test can detect the iodine uptake function of your thyroid gland and help diagnose the cause of hyperthyroidism. For example, low levels of iodine uptake might be a sign of thyroiditis, whereas high levels could indicate Graves’ disease.
 * Thyroid scan: This test may also help diagnose the cause of hyperthyroidism by providing images of nodules and other possible thyroid irregularities.

When to seek urgent medical care?
Call your health care provider if symptoms of hyperthyroidism develop. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:
 * Palpitation
 * Sever hypertension

Treatment options
Usual treatment measures of hyperthyroidism include medications, redioactive iodine and surgery. Treatment opinion depends on the cause, age, physical condition and the severity of symptoms.
 * Medications: Antithyroid medications, such as methimazole (Tapazole) and propylthiouracil (PTU), are used to block the production of thyroid hormone. Symptoms may begin to improve in 6 to 12 weeks and the whole treatment peroid may last for at least a year. Beta blockers, for example propranolol, may used to release symptoms such as palpitation, nervousness, hypertension, sweating and shaking.
 * Radioactive iodine: This kind of treatment may destroy thyroid gland and stop the excess production of hormones. During this peroid, the patient takes radioactive iodine by mouth. Common side effect is permanent hypothyroidism, which needs thyroid supplements.
 * Surgery: Thyroidectomy is another type of treatment opinion. The possible side effect after surgery is hypothyroidism. Patients need to take thyroid hormone supplement to restore normal hormone levels.

Diseases with similar symptoms

 * Goiter
 * Thyroid cancer
 * Autonomic nerve dysfunction
 * Coronary artery disease
 * Schizophrenia

Where to find medical care for hyperthyroidism?
Directions to Hospitals Treating hyperthyroidism

Prevention of hyperthyroidism

 * For hyperthyroidism caused by too much of iodine ingestion, prevention measure is decreasing iodine ingestion and regular check blood levels of thyroid hormone.
 * For hyperthyroidism caused by overmedicating with synthetic thyroid hormone, appropriate dose to patients and regulatr check of blood levels of thyroid hormone may be important.

What to expect (Outook/Prognosis)?
Many cases of hyperthyroidism are generally treatable. Prognosis depends on whether the patient gets severe complcations.

Copyleft Sources
http://www.endocrine.niddk.nih.gov/pubs/Hyperthyroidism/

http://familydoctor.org/online/famdocen/home/common/hormone/869.printerview.html

http://www.nlm.nih.gov/medlineplus/ency/article/000356.htm