Uricosuric

Uricosuric substances are substances which increase the excretion of uric acid, thus reducing its concentrations in plasma.

This is typically by action on the distal renal tubule.

Examples include probenecid and sulfinpyrazone, which are used occasionally in treatment of gout. Losartan an angiotensin II blocker also has uricosuric properties. All diuretics raise uric acid levels - anti uricosuric!