Galactosylceramide sulfotransferase

In enzymology, a galactosylceramide sulfotransferase is an enzyme that catalyzes the chemical reaction


 * 3'-phosphoadenylyl sulfate + a galactosylceramide $$\rightleftharpoons$$ adenosine 3',5'-bisphosphate + a galactosylceramidesulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and galactosylceramide, whereas its two products are adenosine 3',5'-bisphosphate and galactosylceramidesulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase. Other names in common use include GSase, 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase, galactocerebroside sulfotransferase, galactolipid sulfotransferase, glycolipid sulfotransferase, and glycosphingolipid sulfotransferase. This enzyme participates in sphingolipid metabolism.