Pyridoxine 5'-phosphate synthase

In enzymology, a pyridoxine 5'-phosphate synthase is an enzyme that catalyzes the chemical reaction


 * 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate $$\rightleftharpoons$$ pyridoxine 5'-phosphate + phosphate + 2 H2O

Thus, the two substrates of this enzyme are 1-deoxy-D-xylulose 5-phosphate and 3-amino-2-oxopropyl phosphate, whereas its 3 products are pyridoxine 5'-phosphate, phosphate, and H2O.

This enzyme belongs to the family of transferases, specifically those transferring nitrogenous groups transferring other nitrogenous groups. The systematic name of this enzyme class is 1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing). Other names in common use include pyridoxine 5-phosphate phospho lyase, PNP synthase, and PdxJ. This enzyme participates in vitamin b6 metabolism.