Alteplase drug interactions

Drug Interactions of Alteplase
General Nitroglycerin Incompatibility Laboratory Test Interactions Complete list of drug interactions ---

General
Anticoagulants (e.g., warfarin, heparin), aspirin, drugs affecting platelet function (e.g, abciximab, dipyridamole), vitamin K antagonists may increase the risk of bleeding.

Return to top

Nitroglycerin
May reduce alteplase concentrations, decreasing the thrombolytic effect.

Return to top

Incompatibility
Do not add other medications to infusion solution.

Return to top

Laboratory Test Interactions
Results of tests for coagulation or fibrinolytic activity may be unreliable because of degradation of fibrinogen in blood.

Return to top

Major Interactions

 * abciximab
 * Acova
 * Aggrastat
 * Angiomax
 * anisindione
 * Aptivus
 * ardeparin
 * argatroban
 * Arixtra
 * Arixtra 10 mg/dose
 * Arixtra 5 mg/dose
 * Arixtra 7.5 mg/dose
 * Bexxar Dosimetric
 * Bexxar I 131 Dosimetric
 * Bexxar I 131 Therapeutic
 * BexxarTherapeutic
 * bivalirudin
 * Clexane
 * Clexane Forte
 * Coumadin
 * dalteparin
 * danaparoid
 * dasatinib
 * desirudin
 * dicumarol
 * drotrecogin
 * drotrecogin alfa
 * enoxaparin
 * eptifibatide
 * fondaparinux
 * Fragmin
 * Hep-Lock
 * Hep-Pak
 * Hep-Pak CVC
 * heparin
 * Heparin Lock Flush
 * ibritumomab
 * In-111 Zevalin
 * Innohep
 * Integrilin
 * iodine I 131 tositumomab
 * Iprivask
 * Jantoven
 * lepirudin
 * Lovenox
 * Lovenox HP
 * Miradon
 * Normiflo
 * Orgaran
 * Refludan
 * Reopro
 * Sprycel
 * tinzaparin
 * tipranavir
 * tirofiban
 * tositumomab
 * warfarin
 * Xigris
 * Y-90 Zevalin

Return to top

Moderate Interactions

 * Acetylsalicylic Acid
 * Actron
 * Acular
 * Acular LS
 * Acular PF
 * Acuprin 81
 * Advil
 * Advil Childrens
 * Advil Junior Strength
 * Advil Liquigel
 * Advil Migraine
 * Advil Pediatric
 * Aflaxen
 * Aleve
 * Aleve Caplet
 * Aleve Easy Open Arthritis
 * Aleve Gelcap
 * Amigesic
 * Anaflex
 * Anafranil
 * Anaprox
 * Anaprox-DS
 * Ansaid
 * Argesic-SA
 * Arthritis Pain
 * Arthropan
 * ASA
 * Ascriptin Enteric
 * Aspergum Cherry
 * Aspergum Orginal
 * Aspir-Low
 * aspirin
 * aspirin extended release
 * Aspirin Lite Coat
 * Aspirin Litecoat
 * Aspirin Low Strength
 * Aspirtab
 * Bayer Aspirin
 * Bayer Aspirin Regimen
 * Bayer Aspirin Sugar Free
 * Bayer Aspirin with Calcium
 * Bayer Childrens Aspirin
 * Bayer Low Strength
 * Bayer Plus
 * Bayer Select Backache Pain Formula
 * Bismarex
 * Bismatrol
 * Bismatrol Maximum Strength
 * bismuth subsalicylate
 * bromfenac
 * bromfenac ophthalmic
 * Buffered Aspirin
 * Bufferin
 * Bufferin Arthritis Strength
 * Bufferin Extra Strength
 * Buffex
 * Cataflam
 * Celexa
 * Ceprotin
 * Childrens Ibuprofen Berry
 * Childrens Kaopectate
 * choline salicylate
 * citalopram
 * Clinoril
 * Clomipramine
 * clopidogrel
 * Cymbalta
 * Daypro
 * Deponit
 * desvenlafaxine
 * dexfenfluramine
 * diclofenac
 * diclofenac ophthalmic
 * diclofenac potassium
 * diclofenac sodium
 * diclofenac sodium extended release
 * diclofenac topical
 * diflunisal
 * Dilatrate-SR
 * dipyridamole
 * Disalcid
 * Doans Pills
 * Doans Pills Extra Strength
 * Dolobid
 * dong quai
 * duloxetine
 * DurAct
 * Easprin
 * EC-Naprosyn
 * Ecotrin
 * Ecotrin Adult Low Strength
 * Ecotrin Maximum Strength
 * Effexor
 * Effexor XR
 * Elmiron
 * Empirin
 * Entaprin
 * Entercote
 * epoprostenol
 * escitalopram
 * etodolac
 * etodolac extended release
 * Extra Strength Bayer
 * Fasprin
 * Feldene
 * fenfluramine
 * fenoprofen
 * Flector Patch
 * Flolan
 * fluoxetine
 * fluoxetine extended release
 * flurbiprofen
 * flurbiprofen ophthalmic
 * fluvoxamine
 * fluvoxamine extended release
 * garlic
 * Garlic Oil
 * Genacote
 * Gennin-FC
 * Genpril
 * Genprin
 * ginger
 * Ginger Root
 * Ginger (obs)
 * gingko
 * gingko biloba
 * ginseng
 * Halfprin
 * Haltran
 * hemin
 * Hofels Ginger One A Day
 * Ibu
 * IBU-200
 * Ibu-4
 * Ibu-6
 * Ibu-8
 * Ibu-Tab
 * ibuprofen
 * Ibuprofen PMR
 * iloprost
 * Imdur
 * Indocin
 * Indocin SR
 * indomethacin
 * indomethacin extended release
 * ISDN
 * ISMO
 * Isochron
 * Isordil
 * Isordil Tembids
 * Isordil Titradose
 * isosorbide dinitrate
 * isosorbide dinitrate extended release
 * isosorbide mononitrate
 * isosorbide mononitrate extended release
 * K-Pek
 * Kao-Tin Bismuth Subsalicylate Formula
 * Kaopectate
 * Kaopectate Anti-Diarrheal Upset Stomach Reliever
 * Kaopectate Extra Strength
 * Kapectolin (New Formula)
 * ketoprofen
 * ketoprofen extended release
 * ketorolac
 * ketorolac ophthalmic
 * Leader Naproxen Sodium
 * Lexapro
 * Litecoat Aspirin
 * Lodine
 * Lodine XL
 * Low Dose ASA
 * Luvox
 * Luvox CR
 * Maalox Total Stomach Relief
 * Magan
 * magnesium salicylate
 * Marthritic
 * Maximum Strength Stress
 * meclofenamate
 * Meclomen
 * mefenamic acid
 * meloxicam
 * Menadol
 * Meridia
 * Midol Extended Relief
 * Midol IB
 * Midol Maximum Strength Cramp Formula
 * Minitabs
 * Minitran
 * Mobic
 * Mobidin
 * Mono-Gesic
 * Monoket
 * Motrin
 * Motrin Childrens
 * Motrin IB
 * Motrin Infant Drops
 * Motrin Junior Strength
 * Motrin Migraine Pain
 * MST
 * nabumetone
 * Nalfon
 * Naprelan '375'
 * Naprelan '500'
 * Naprosyn
 * naproxen
 * naproxen sodium
 * Naproxen Sodium DS
 * naproxen sodium extended release
 * NeoProfen
 * nepafenac ophthalmic
 * Nevanac
 * Nitrek
 * Nitro TD Patch-A
 * Nitro-Bid
 * Nitro-Bid IV
 * Nitro-Dur
 * Nitro-Par
 * Nitro-Time
 * Nitrocot
 * Nitrodisc
 * Nitrogard
 * nitroglycerin
 * Nitroglyn E-R
 * Nitrol
 * Nitrol Appli-Kit
 * Nitrolingual
 * Nitrong
 * Nitroquick
 * Nitrostat
 * Norwich Aspirin
 * NTG
 * Nuprin
 * Nuprin Backache Caplet
 * Ocufen
 * Orudis
 * Orudis KT
 * Oruvail
 * oxaprozin
 * Panhematin
 * paroxetine
 * paroxetine extended release
 * paroxetine mesylate
 * Paxil
 * Paxil CR
 * Pediacare Fever
 * pentosan polysulfate sodium
 * Peptic Relief
 * Pepto-Bismol
 * Pepto-Bismol Maximum Strength
 * Persantine
 * Persantine IV
 * Pexeva
 * phenyl salicylate
 * phenylbutazone
 * Pink Bismuth
 * piroxicam
 * Plavix
 * Pondimin
 * Ponstel
 * Pristiq
 * prostacyclin
 * protein C
 * Protexel
 * Prozac
 * Prozac Weekly
 * Q-Profen
 * Rapiflux
 * Redux
 * Relafen
 * Remodulin
 * Rexolate
 * Rufen
 * Saleto-200
 * Saleto-400
 * Saleto-600
 * Saleto-800
 * Salflex
 * salsalate
 * Salsitab
 * Sarafem
 * Selfemra
 * sertraline
 * sibutramine
 * Sloprin
 * sodium salicylate
 * sodium thiosalicylate
 * Solaraze
 * Sorbitrate
 * St. Joseph Aspirin
 * St. Joseph Aspirin Adult Chewable
 * St. Joseph Aspirin Adult EC
 * Stanback Analgesic
 * Stress Maximum Strength
 * sulindac
 * suprofen ophthalmic
 * Therapy Bayer
 * Ticlid
 * ticlopidine
 * Tolectin
 * Tolectin 600
 * Tolectin DS
 * tolmetin
 * Toradol
 * Toradol IM
 * Toradol IV/IM
 * treprostinil
 * Tri-Buffered Aspirin
 * Tridil
 * Tusal
 * venlafaxine
 * venlafaxine extended release
 * Ventavis
 * Voltaren
 * Voltaren Ophthalmic
 * Voltaren Topical
 * Voltaren-XR
 * Xibrom
 * YSP Aspirin
 * Zero-Order Release
 * zingiber
 * Zoloft
 * Zorprin

Return to top

Minor Interactions

 * capsaicin
 * capsicum
 * chamomile
 * clove
 * fenugreek
 * feverfew
 * matricaria
 * turmeric

Return to top