NMN nucleosidase

In enzymology, a NMN nucleosidase is an enzyme that catalyzes the chemical reaction


 * nicotinamide D-ribonucleotide + H2O $$\rightleftharpoons$$ D-ribose 5-phosphate + nicotinamide

Thus, the two substrates of this enzyme are nicotinamide D-ribonucleotide and H2O, whereas its two products are D-ribose 5-phosphate and nicotinamide.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is nicotinamide-nucleotide phosphoribohydrolase. Other names in common use include NMNase, nicotinamide mononucleotide nucleosidase, nicotinamide mononucleotidase, NMN glycohydrolase, and NMNGhase. This enzyme participates in nicotinate and nicotinamide metabolism.