The Living Guidelines: STEMI Recommendations for Inhibition of the Renin-Angiotensin-Aldosterone System Suggest Revisions to the CLASS IIa Guidelines

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Class IIa

 * 1) In STEMI patients who tolerate ACE inhibitors, an ARB can be useful as an alternative to ACE inhibitors in the long-term management of STEMI patients, provided there are either clinical or radiological signs of heart failure or LVEF less than 0.40. Valsartan and candesartan have established efficacy for this recommendation. (Level of Evidence: B)