Sirohydrochlorin ferrochelatase

In enzymology, a sirohydrochlorin ferrochelatase is an enzyme that catalyzes the chemical reaction


 * siroheme + 2 H+ $$\rightleftharpoons$$ sirohydrochlorin + Fe2+

Thus, the two substrates of this enzyme are siroheme and H+, whereas its two products are sirohydrochlorin and Fe2+.

This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that do not fit into any other sub-class. The systematic name of this enzyme class is siroheme ferro-lyase (sirohydrochlorin-forming). Other names in common use include CysG, Met8P, SirB, and sirohydrochlorin ferro-lyase (incorrect). This enzyme participates in porphyrin and chlorophyll metabolism.