Malignant fibrous histiocytoma history and symptoms

Presentation
MFH occurs most commonly in the extremities and retroperitoneum, but has been reported in many other sites (lung, head/neck, etc.). Development of metastasis depends on the tumor's subtype. Metastasis occurs most frequently in the lung (90%), bone (8%) and liver (1%). In the extremities, it presents as a painless enlarging soft tissue mass. It can develop anywhere in the soft tissue, but also occurs at sites of previous radiation treatment, shrapnel implantation or next to prostheses.