Ferredoxin-NAD+ reductase

In enzymology, a ferredoxin---NAD+ reductase is an enzyme that catalyzes the chemical reaction


 * reduced ferredoxin + NAD+ $$\rightleftharpoons$$ oxidized ferredoxin + NADH + H+

Thus, the two substrates of this enzyme are reduced ferredoxin and NAD+, whereas its 3 products are oxidized ferredoxin, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on iron-sulfur proteins as donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ferredoxin:NAD+ oxidoreductase. Other names in common use include ferredoxin-nicotinamide adenine dinucleotide reductase, ferredoxin reductase, NAD+-ferredoxin reductase, NADH-ferredoxin oxidoreductase, reductase, reduced nicotinamide adenine dinucleotide-ferredoxin, ferredoxin-NAD+ reductase, NADH-ferredoxin reductase, NADH2-ferredoxin oxidoreductase, NADH flavodoxin oxidoreductase, NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase, multicomponent enzyme system), ferredoxin-linked NAD+ reductase, NADH-ferredoxinTOL reductase (component of toluene dioxygenase), and ferredoxin---NAD reductase. This enzyme participates in fatty acid metabolism.

Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code.