Fondaparinux overdose

Overdose
There is no known antidote for Arixtra Injection. Overdose of Arixtra may lead to hemorrhagic complications. Overdosage associated with bleeding complications should lead to treatment discontinuation and initiation of appropriate therapy.

Data obtained in patients undergoing chronic intermittent hemodialysis suggest that clearance of Arixtra can increase by 20% during hemodialysis.