Fixed drug eruption

Prescription or over the counter medications can cause many skin reactions. A fixed drug eruption is an uncommon occurrence characterized by a specific area of skin on a person's body becoming painfully inflamed after consumption of the drug. The face, genitalia, palms of the hands, soles of the feet, knees and elbows typically exhibit the reaction. The reaction will typically occur in the exact same("fixed") location each time the person takes the same medication again.