The Living Guidelines: UA/NSTEMI Recomendations for PCI Suggest Revisions to the CLASS I Guidelines

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1. An early invasive PCI strategy is indicated for patients with UA/ NSTEMI who have no serious comorbidity and who have coronary lesions amenable to PCI and any of the high-risk features listed in Section 3.3. (See Section 3.3 for specific recommendations and their Level of Evidence.)
 * Class I

2. Percutaneous coronary intervention (or CABG) is recommended for UA/NSTEMI patients with 1- or 2-vessel CAD with or without significant proximal left anterior descending CAD but with a large area of viable myocardium and high-risk criteria on noninvasive testing. (Level of Evidence: B)

3. Percutaneous coronary intervention (or CABG) is recommended for UA/NSTEMI patients with multivessel coronary disease with suitable coronary anatomy, with normal LV function, and without diabetes mellitus. (Level of Evidence: A)

4. An intravenous platelet GP IIb/IIIa inhibitor is generally recommended in UA/NSTEMI patients undergoing PCI. (Level of Evidence: A) See Section 3.2.3 and Figures 7, 8, and 9 for details on timing and dosing recommendations.