Atovaquone (patient information)

Why this medication is prescribed
Atovaquone is used to treat Pneumocystis carinii pneumonia (PCP).

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How this medication should be used
Atovaquone comes as a liquid to take by mouth. It usually is taken with food every 8 hours for 21 days. Always take atovaquone with snacks or meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take atovaquone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Special precautions
Before taking atovaquone:


 * tell your doctor and pharmacist if you are allergic to atovaquone or any other drugs.
 * tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially rifampin (Rifadin), sulfa drugs, zidovudine and vitamins.
 * tell your doctor if you have or have ever had stomach or intestinal disorders or allergies.
 * tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking atovaquone, call your doctor.
 * you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
 * remember that alcohol can add to the drowsiness caused by this drug.

What to do if you forget a dose
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Minor Side Effects
Atovaquone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:


 * upset stomach
 * diarrhea
 * constipation
 * headache
 * difficulty sleeping
 * sweating
 * dizziness
 * altered sense of taste

Severe Side Effects
If you experience any of the following symptoms, call your doctor immediately:


 * skin rash
 * fever
 * vomiting
 * itching
 * unusual weakness

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

Storage conditions needed for this medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Other information
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to atovaquone.

Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the atovaquone, call your doctor.

Brand names

 * Mepron®