Dual-specificity kinase

In enzymology, a dual-specificity kinase is an enzyme that catalyzes the chemical reaction


 * ATP + a protein $$\rightleftharpoons$$ ADP + a phosphoprotein

Thus, the two substrates of this enzyme are ATP and protein, whereas its two products are ADP and phosphoprotein.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups dual-specificity kinases (those acting on Ser/Thr and Tyr residues). The systematic name of this enzyme class is ATP:protein phosphotransferase (Ser/Thr- and Tyr-phosphorylating). Other names in common use include ADK1, Arabidopsis dual specificity kinase 1, CLK1, dDYRK2, and Mps1p. This enzyme participates in cell cycle - yeast.