Kanamycin kinase

In enzymology, a kanamycin kinase is an enzyme that catalyzes the chemical reaction


 * ATP + kanamycin $$\rightleftharpoons$$ ADP + kanamycin 3'-phosphate

Thus, the two substrates of this enzyme are ATP and kanamycin, whereas its two products are ADP and kanamycin 3'-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:kanamycin 3'-O-phosphotransferase. This enzyme is also called neomycin-kanamycin phosphotransferase.

Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , and.