Sodium-iodide symporter

The sodium-iodide symporter is an ion pump that transports Iodide (I-) into thyroid epithelial cells. This is an important step in the process of iodide organification and the formation of triiodothyronine (T3) and thyroxine (T4). This pump is the target of certain anion based inhibitors such as perchlorate, pertechnate, and thiocyanate.