Inositol-phosphate phosphatase

In enzymology, an inositol-phosphate phosphatase is an enzyme that catalyzes the chemical reaction


 * myo-inositol phosphate + H2O $$\rightleftharpoons$$ myo-inositol + phosphate

Thus, the two substrates of this enzyme are myo-inositol phosphate and H2O, whereas its two products are myo-inositol and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is myo-inositol-phosphate phosphohydrolase. Other names in common use include myo-inositol-1(or 4)-monophosphatase, inositol 1-phosphatase, L-myo-inositol-1-phosphate phosphatase, myo-inositol 1-phosphatase, inositol phosphatase, inositol monophosphate phosphatase, inositol-1(or 4)-monophosphatase, myo-inositol-1(or 4)-phosphate phosphohydrolase, myo-inositol monophosphatase, and myo-inositol-1-phosphatase. This enzyme participates in 3 metabolic pathways: streptomycin biosynthesis, inositol phosphate metabolism, and phosphatidylinositol signaling system.

Structural studies
As of late 2007, 26 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , , , , , , , , , , , , , , , , , and.