Duodenal atresia

Overview
Duodenal atresia is the congenital absence or complete closure of a portion of the lumen of the duodenum. Approximately 20-40% of all infants with duodenal atresia have Down syndrome. It is also associated with polyhydramnios which is increased amniotic fluid in the uterus.

Diagnosis
The diagnosis of duodenal atresia is usually confirmed by radiography. An X-ray of the abdomen shows two large air filled spaces, the so-called "double bubble" sign. The air is trapped in the stomach and duodenum. Since the closure of the duodenum is complete in duodenal atresia, no air is seen distal to the duodenum.