Prempro drug interactions

Prempro is a multi-ingredient drug consisting of:


 * medroxyprogesterone
 * conjugated estrogens

Interactions with each of its ingredients have been shown below:

Major Interactions
Accutane, acitretin, Agenerase, Amnesteem, amprenavir, bexarotene, bosentan, Claravis, etretinate, fosamprenavir, Fulvicin P/G, Fulvicin U/F, Grifulvin V, Gris-PEG, Grisactin 250, Grisactin 500, Grisactin Ultra, Griseofulicin, Griseofulvic, griseofulvin, griseofulvin microsize, griseofulvin ultramicrosize, isotretinoin, Lexiva, Soriatane, Soriatane CK, Sotret, Targretin, Tegison, Telzir, Tracleer

Moderate Interactions
acarbose, acetoHEXAMIDE, Adrenocot, Adrenocot L.A., Amaryl, aminoglutethimide, amobarbital, Amytal Sodium, Anturane, Apidra, Apidra OptiClik Cartridge, aprepitant, armodafinil, atazanavir, Busodium, butabarbital, butalbital, Butisol Sodium, carbamazepine, carbamazepine extended release, Carbatrol, Cardizem, Cardizem CD, Cardizem LA, Cardizem Monovial, Cardizem SR, Cartia XT, Cerebyx, chlorproPAMIDE, Clopine, clotrimazole, clozapine, Clozapine Synthon, Clozaril, conivaptan, Cortastat, Cortastat 10, Cortastat LA, Cytadren, Dalalone, Dalalone D.P., Dalalone L.A., dalfopristin, dasatinib, De-Sone LA, Decadron, Decadron 5-12 Pak, Decadron Phosphate, Injectable, Decadron-LA, Decaject, Decaject L.A., Denzapine, Depacon, Depakene, Depakote, Depakote ER, Depakote Sprinkles, Dexacen-4, Dexacort Phosphate in Respihaler, Dexacort-LA, Dexacorten, dexamethasone, dexamethasone acetate, Dexamethasone Intensol, dexamethasone sodium phosphate, Dexasone, Dexasone LA, Dexone, Dexone LA, Dexpak Jr. Taperpak, Dexpak Taperpak, Di-Phen, DiaBeta, Diabinese, Diflucan, Dilacor XR, Dilantin, Dilantin Infatabs, Dilantin Kapseals, Dilantin-125, Diltia XT, diltiazem, diltiazem 24 hour extended release, diltiazem extended release, Diltiazem Hydrochloride CD, Diltiazem Hydrochloride SR, Diltiazem Hydrochloride XR, Diltiazem Hydrochloride XT, divalproex sodium, divalproex sodium extended release, Dymelor, efavirenz, Emend, Emend 3-Day, Emend for Injection, Epitol, Equetro, etravirine, EXUBERA, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, FazaClo, felbamate, Felbatol, FK506, fluconazole, fluvoxamine, fluvoxamine extended release, Fortamet, Fortovase, fosaprepitant, fosphenytoin, Genotropin, Genotropin Miniquick, Gleevec, glimepiride, glipiZIDE, glipiZIDE extended release, GlipiZIDE XL, Glucophage, Glucophage XR, Glucotrol, Glucotrol XL, Glumetza, glyBURIDE, glyBURIDE micronized, Glynase PresTab, Glyset, grepafloxacin, Hexadrol, Hexadrol Phosphate, Humalog, Humalog Cartridge, Humalog KwikPen, Humalog Pen, Humatrope, Humulin L, Humulin N, Humulin N Pen, Humulin R, Humulin R (Concentrated), Humulin U, hypericum perforatum, Iletin II Lente Pork, Iletin II NPH Pork, Iletin II Regular Pork, Iletin Lente, Iletin NPH, Iletin Regular, imatinib, insulin, insulin analog, insulin aspart, insulin aspart protamine, insulin detemir, insulin glargine, insulin glulisine, insulin inhalation, rapid acting, insulin isophane, Insulin Lente Pork, insulin lispro, insulin lispro protamine, Insulin Purified NPH Pork, Insulin Purified Regular Pork, insulin regular, insulin zinc, insulin zinc extended, insulin, lente, insulin, NPH, insulin, ultralente, Intelence, Invirase, itraconazole, Januvia, Ketek, Ketek Pak, ketoconazole, Lamictal, Lamictal Blue, Lamictal CD, Lamictal Green, Lamictal Orange, lamotrigine, Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen, lapatinib, Lente insulin, Levemir, Levemir FlexPen, Levemir InnoLet, Levemir PenFill, Luminal, Luvox, Luvox CR, Mebaral, Medidex, Medidex LA, mephobarbital, metformin, metformin extended release, mibefradil, miconazole, Micronase, Mifeprex, mifepristone, miglitol, modafinil, Monistat I.V., Mycelex Troche, Mycobutin, Mysoline, nateglinide, nefazodone, nelfinavir, Nembutal, Nembutal Sodium, nevirapine, nilotinib, Nizoral, Norditropin, Norditropin Cartridge, Norditropin Nordiflex Pen, Norvir, Norvir Soft Gelatin, Novolin L, Novolin N, Novolin N Innolet, Novolin N PenFill, Novolin R, Novolin R Innolet, Novolin R PenFill, NovoLog, NovoLog FlexPen, NovoLog PenFill, NPH insulin, Nutropin, Nutropin AQ, Nutropin Depot, Nuvigil, Omnitrope, Omnitrope Pen 5, Orinase, oxcarbazepine, pentobarbital, phenobarbital, phenylbutazone, Phenytek, phenytoin, phenytoin extended release, Phenytoin Sodium, Prompt, Posicor, Prandin, Precose, Priftin, Primethasone, primidone, Prograf, protamine zinc insulin, Protropin, Provigil, Rapamune, Raxar, regular insulin, ReliOn/Novolin N, ReliOn/Novolin R, repaglinide, Reyataz, Rezulin, rifabutin, Rifadin, Rifadin IV, rifampin, rifapentine, Rimactane, Riomet, ritonavir, RU-486, Saizen, saquinavir, saquinavir mesylate, secobarbital, Seconal Sodium, Serostim, Serzone, sirolimus, sitagliptin, sodium valproate, Solfoton, Solurex, Solurex LA, somatrem, somatropin, Sporanox, Sprycel, St. John's wort, Starlix, sulfinpyrazone, Sustiva, tacrolimus, Tasigna, Taztia XT, Tegretol, Tegretol XR, telithromycin, Tev-tropin, Tiazac, Tol-Tab, TOLAZamide, TOLBUTamide, Tolinase, Trileptal, troglitazone, Tykerb, Ultralente insulin, valproic acid, Vaprisol, Velosulin BR, VFEND, Viracept, Viramune, voriconazole, Zaponex, Zorbtive

Minor Interactions
Actos, atorvastatin, Chem Mart Tamoxifen, Crestor, Crixivan, delavirdine, Emblon, Genox, GenRx Tamoxifen, indinavir, Lipitor, Nolvadex, Nolvadex D, pioglitazone, Rescriptor, rosuvastatin, Soltamox, Tamofen, Tamofen(obsolete), Tamone, Tamosin, Tamoxen, tamoxifen, Tamoxifen Hexal, Terry White Chemists Tamoxifen

Major Interactions
Dantrium, Dantrium Intravenous, dantrolene, hemin, Panhematin

Moderate Interactions
A-Hydrocort, A-Methapred, acarbose, Acetocot, acetoHEXAMIDE, ACTH, ACTH Gel, ACTH-40 HP, ACTH-80, Acthar, Acthar Gel, H.P., Acthrel, Adbeon, Adlone-40, Adlone-80, Adrenocot, Adrenocot L.A., Amaryl, aminoglutethimide, amobarbital, Amytal Sodium, anastrozole, anisindione, Anturane, Apidra, Apidra OptiClik Cartridge, aprepitant, Aptivus, Arimidex, Aristocort, Aristocort For Injection, Aristocort Forte, Aristopak, Aristospan Injection, Armour Thyroid, Aromasin, Azmacort, Beta-Phos/AC, betamethasone, betamethasone acet-betamethasone na phosphate, betamethasone sodium phosphate, bexarotene, bosentan, Bubbli-Pred, Busodium, butabarbital, butalbital, Butisol Sodium, carbamazepine, carbamazepine extended release, Carbatrol, Cardizem, Cardizem CD, Cardizem LA, Cardizem Monovial, Cardizem SR, Cartia XT, Celestone, Celestone Phosphate, Celestone Soluspan, Cell-U-Jec, Cerebyx, chlorproPAMIDE, Clinacort, Clinalog, clotrimazole, Colocort, conivaptan, Cort-K, Cortastat, Cortastat 10, Cortastat LA, Cortef, Cortenema, corticorelin, corticotropin, Cortifoam, cortisone, Cortone Acetate, Cortrosyn, cosyntropin, Cotolone, Coumadin, Cytadren, Cytomel, Dalalone, Dalalone D.P., Dalalone L.A., dasatinib, De-Sone LA, Decadron, Decadron 5-12 Pak, Decadron Phosphate, Injectable, Decadron-LA, Decaject, Decaject L.A., Deltasone, Dep Medalone 80, Depacon, Depakene, Depakote, Depakote ER, Depakote Sprinkles, Depmedalone, Depo-Medrol, Depo-Predate (obsolete), Depoject-80, Depopred, Dexacen-4, Dexacort Phosphate in Respihaler, Dexacort-LA, Dexacorten, dexamethasone, dexamethasone acetate, Dexamethasone Intensol, dexamethasone sodium phosphate, Dexasone, Dexasone LA, Dexone, Dexone LA, Dexpak Jr. Taperpak, Dexpak Taperpak, Di-Phen, DiaBeta, Diabinese, dicumarol, Diflucan, Dilacor XR, Dilantin, Dilantin Infatabs, Dilantin Kapseals, Dilantin-125, Diltia XT, diltiazem, diltiazem 24 hour extended release, diltiazem extended release, Diltiazem Hydrochloride CD, Diltiazem Hydrochloride SR, Diltiazem Hydrochloride XR, Diltiazem Hydrochloride XT, divalproex sodium, divalproex sodium extended release, Duralone, Dymelor, efavirenz, Eltroxin, Emend, Emend 3-Day, Emend for Injection, Epitol, Equetro, Euthyrox, Eutroxsig, Evista, Evotrox, exemestane, EXUBERA, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, felbamate, Felbatol, Femara, Flo-Pred, Florinef Acetate, fluconazole, fludrocortisone, fluvoxamine, fluvoxamine extended release, Fortamet, Fortovase, fosaprepitant, fosphenytoin, Fulvicin P/G, Fulvicin U/F, Gleevec, glimepiride, glipiZIDE, glipiZIDE extended release, GlipiZIDE XL, Glucophage, Glucophage XR, Glucotrol, Glucotrol XL, Glumetza, glyBURIDE, glyBURIDE micronized, Glynase PresTab, Glyset, Grifulvin V, Gris-PEG, Grisactin 250, Grisactin 500, Grisactin Ultra, Griseofulicin, Griseofulvic, griseofulvin, griseofulvin microsize, griseofulvin ultramicrosize, Hexadrol, Hexadrol Phosphate, Humalog, Humalog Cartridge, Humalog KwikPen, Humalog Pen, Humulin L, Humulin N, Humulin N Pen, Humulin R, Humulin R (Concentrated), Humulin U, Hydeltra-T.B.A., Hydeltrasol, hydrocortisone, hydrocortisone acetate, hydrocortisone cypionate, hydrocortisone hemisuccinate, hydrocortisone sodium phosphate, Hydrocortisone Sodium Succinate, Hydrocortone, Hydrocortone Phosphate, hypericum perforatum, Iletin II Lente Pork, Iletin II NPH Pork, Iletin II Regular Pork, Iletin Lente, Iletin NPH, Iletin Regular, imatinib, insulin, insulin analog, insulin aspart, insulin aspart protamine, insulin detemir, insulin glargine, insulin glulisine, insulin inhalation, rapid acting, insulin isophane, Insulin Lente Pork, insulin lispro, insulin lispro protamine, Insulin Purified NPH Pork, Insulin Purified Regular Pork, insulin regular, insulin zinc, insulin zinc extended, insulin, lente, insulin, NPH, insulin, ultralente, Invirase, itraconazole, Jantoven, Januvia, Ken-Jec 40, Kenaject-40, Kenalog-10, Kenalog-40, Ketek, Ketek Pak, ketoconazole, Key-Pred, Key-Pred SP, L THYROXINE ROCHE, l-thyroxine, Lamictal, Lamictal Blue, Lamictal CD, Lamictal Green, Lamictal Orange, lamotrigine, Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen, lapatinib, Lente insulin, letrozole, Levemir, Levemir FlexPen, Levemir InnoLet, Levemir PenFill, Levo-T, Levotabs, Levotec, Levothroid, LEVOTHYROX, levothyroxine, Levoxyl, liothyronine, liotrix, Liquid Pred, Luminal, Luvox, Luvox CR, M-PREDNISolone, Mebaral, Med-Jec-40, Medicort, Medidex, Medidex LA, Medipred, Medralone, Medralone 40, Medralone 80, Medrol, Medrol Dosepak, mephobarbital, metformin, metformin extended release, Methacort 40, Methacort 80, Methylcotol, Methylcotolone, Methylpred DP, methylPREDNISolone, methylPREDNISolone acetate, MethylPREDNISolone Dose Pack, methylPREDNISolone sodium succinate, Meticorten, Metopirone, metyrapone, mibefradil, miconazole, Micronase, Mifeprex, mifepristone, miglitol, Millipred, Miradon, Monistat I.V., Mycelex Troche, Mycobutin, Mysoline, nateglinide, Nature-Throid, nefazodone, Nembutal, Nembutal Sodium, nevirapine, nilotinib, Nizoral, Novolin L, Novolin N, Novolin N Innolet, Novolin N PenFill, Novolin R, Novolin R Innolet, Novolin R PenFill, NovoLog, NovoLog FlexPen, NovoLog PenFill, NPH insulin, Orapred, Orapred ODT, Orasone, Orinase, Oroxine, oxcarbazepine, Pediapred, pentobarbital, phenobarbital, phenylbutazone, Phenytek, phenytoin, phenytoin extended release, Phenytoin Sodium, Prompt, Posicor, Prandin, Precose, Pred-Ject-50, Predacort 50, Predacorten, Predaject-50, Predalone 50, Predate-50, Predcor, Predicort RP, Predicort-50, Prednicen-M, Prednicot, prednisoLONE, prednisoLONE acetate, prednisoLONE sodium phosphate, prednisoLONE tebutate, predniSONE, Prelone, Pri-Cortin 50, Priftin, Primethasone, primidone, protamine zinc insulin, raloxifene, regular insulin, ReliOn/Novolin N, ReliOn/Novolin R, repaglinide, Repreve, Requip, ReQuip Follow on Pack, Requip Starter Kit, ReQuip Starter Pack, Rezulin, rifabutin, Rifadin, Rifadin IV, rifampin, rifapentine, Rimactane, Riomet, ropinirole, RU-486, saquinavir, saquinavir mesylate, secobarbital, Seconal Sodium, Selestoject, Serzone, sitagliptin, sodium valproate, Solfoton, Solu-Cortef, Solu-Medrol, Solurex, Solurex LA, Sporanox, Sprycel, St. John's wort, Starlix, Sterapred, Sterapred DS, sulfinpyrazone, Sustiva, Synthroid, TAC 3, Targretin, Tasigna, Taztia XT, Tegretol, Tegretol XR, telithromycin, Teslac, testolactone, thyroid desiccated, Thyrolar-1, Thyrolar-1/2, Thyrolar-1/4, Thyrolar-2, Thyrolar-3, Tiazac, tipranavir, Tirosint, Tol-Tab, TOLAZamide, TOLBUTamide, Tolinase, Tracleer, Tramacort-D, Triam-A, Triam-Forte, triamcinolone, triamcinolone acetonide, triamcinolone diacetate, triamcinolone hexacetonide, Triamcot, Triamonide 40, Trileptal, Trilog, Trilone, Triostat, Tristoject, troglitazone, Tykerb, U-Tri-Lone, Ultralente insulin, Unithroid, valproic acid, Vaprisol, Velosulin BR, VFEND, Viramune, voriconazole, warfarin, Westhroid

Minor Interactions
Adapin, amitriptyline, amoxapine, Amphadase, Anafranil, armodafinil, Asendin, atorvastatin, Aventyl HCl, cimetidine, clomiPRAMINE, Crixivan, delavirdine, desipramine, doxepin, Elavil, Endep, etravirine, hyaluronidase, Hydase, Hylenex, imipramine, imipramine pamoate, indinavir, Intelence, Lipitor, modafinil, Norpramin, nortriptyline, Nuvigil, Pamelor, protriptyline, Provigil, Rescriptor, saw palmetto, serenoa, Sinequan, Surmontil, Tagamet, Tagamet HB, Tofranil, Tofranil-PM, trimipramine, Vanatrip, Vitrase, Vivactil, Wydase