Levothyroxine drug interactions

List of drug interactions
Overview Oral anticoagulants Digitalis glycosides Drug-food interactions Drug-laboratory test interactions

Overview
Many drugs affect thyroid hormone pharmacokinetics and metabolism (e.g., absorption, synthesis, secretion, catabolism, protein binding, and target tissue response) and may alter the therapeutic response to Levothyroxine sodium. In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugs. A listing of drug-thyroidal is contained in the FDA label. The list of drug-thyroidal axis interactions in the FDA label may not be comprehensive due to the introduction of new drugs that interact with the thyroidal axis or the discovery of previously unknown interactions. The prescriber should be aware of this fact and should consult appropriate reference sources (e.g., package inserts of newly approved drugs, medical literature) for additional information if a drug-drug interaction with Levothyroxine is suspected. Return to top

Oral anticoagulants
Levothyroxine increases the response to oral anticoagulant therapy. Therefore, a decrease in the dose of anticoagulant may be warranted with correction of the hypothyroid state or when the Levothyroxine sodium dose is increased. Prothrombin time should be closely monitored to permit appropriate and timely dosage adjustments. Return to top

Digitalis glycosides
The therapeutic effects of digitalis glycosides may be reduced by Levothyroxine. Serum digitalis glycoside levels may be decreased when a hypothyroid patient becomes euthyroid, necessitating an increase in the dose of digitalis glycosides. Return to top

Drug-food interactions
Consumption of certain foods may affect Levothyroxine absorption thereby necessitating adjustments in dosing. Soybean flour (infant formula), cotton seed meal, walnuts, and dietary fiber may bind and decrease the absorption of Levothyroxine sodium from the GI tract. Return to top

Drug-laboratory test interactions
Changes in TBG concentration must be considered when interpreting T4 and T3 values, which necessitates measurement and evaluation of unbound (free) hormone and/or determination of the free T4 index (FT4I). Pregnancy, infectious hepatitis, estrogens, estrogen-containing oral contraceptives, and acute intermittent porphyria increase TBG concentrations. Decreases in TBG concentrations are observed in nephrosis, severe hypoproteinemia, severe liver disease, acromegaly, and after androgen or corticosteroid therapy. Familial hyper- or hypo-thyroxine binding globulinemias have been described, with the incidence of TBG deficiency approximating 1 in 9000. Return to top

Moderate Interactions
ABC Plus Senior, ABC to Z, acarbose, Accupril, acetoHEXAMIDE, Acid Relief, ADEKs, Adgyn Estro, Aerodiol, Aerolate III, Aerolate JR, Aerolate SR, Alka-Mints, Alkets, Alkums, Allbee-C 800 with Iron, Aloh-Gel, Alora, Alternagel, Alu-Cap, Alu-Tab, aluminum carbonate, aluminum hydroxide, Amaryl, Ami-Natal Plus One Improved, Amilac, Aminatal Plus, Aminatal Plus New Formula, Aminatal Plus One, Aminate, Aminate with 90 mg Iron, aminophylline, aminophylline extended release, Amitone, amobarbital, Amphojel, Amytal Sodium, Anabolin LA, Andro LA 200, Andro-Cyp 100, Andro-Cyp 200, Androderm, AndroGel, AndroGel 2.5 g/packet, AndroGel 5 g/packet, AndroGel Pump 1.25 g/actuation, Android, Android-10, Android-25, Androlone-D, Andryl 200, Anemagen, Anemagen FA, Anemagen OB, anhydrous calcium iodide, anisindione, Antioxid Caplets, Antioxidant Formula, Antioxidant Ultra Formula, Apatate Forte, Apetimar with Iron, Apidra, Apidra OptiClik Cartridge, AquADEKs, AquADEKs Pediatric, Aquaphyllin, Aquest, Asmalix, Avail Calcium Intensive, B-Plex Plus Minerals, Bacmin, Basaljel, Becomax Rx, Bedol, Bee-Zee, Beelith, Berocca Plus, Berplex Plus, Betamed, Biotin Forte with Zinc, Bright Beginnings, Bronkodyl, Bugs Bunny Complete, Bugs Bunny with Iron Chewable, Busodium, butabarbital, butalbital, Butisol Sodium, Cal Oys, Cal-Gest, Cal-Nate, Calafol Rx, Calcarb, Calcet Plus, Calci Mix, Calci-Chew, CalciFol, CalciFolic-D, Calcionate, Calciquid, Calcitab, calcium acetate, calcium carbonate, calcium citrate, Calcium Concentrate, calcium glubionate, calcium gluconate, calcium lactate, Calcium Liquid Softgel, Calcium Oyster, Calcium Oyster Shell, calcium phosphate, tribasic, Calphron, Caltrate, Caltrate 600 Plus, Caltrate Plus, Caltro, carbamazepine, carbamazepine extended release, Carbatrol, carbonyl iron, Cardoxin, CareNatal DHA, Caromega, Cenestin, Cenogen Ultra, Centavite, Central, Central-Vite, Centrum, Centrum Cardio, Centrum Jr, Centrum Jr with Extra C, Centrum Jr with Extra Calcium, Centrum Kids Complete Dora the Explorer, Centrum Kids Complete SpongeBob SquarePants, Centrum Kids Complete Variety, Centrum Performance, Centrum Silver, Centrum Singles, Century, Century-Vite, Cerovite Advanced Formula, Cerovite Junior, Cerovite Liquid, Cerovite Senior, Certa-Vite, Certa-Vite Senior Plus Lutein, Certagen, Certagen Senior, Certagen Senior with Lutein, Certavite, CertaVite with Lutein, Cezin-S, CF Vite, Chem-Sol, chlorotrianisene, chlorproPAMIDE, Choledyl, Choledyl SA, cholestyramine, Cholestyramine Light, Chooz, Chromagen, Chromagen (obsolete), Chromagen FA, Chromagen FA (obsolete), Chromagen Forte, Chromagen Forte (obsolete), Chromagen OB, Chromatinic, Cipro, Cipro Cystitis Pack, Cipro I.V., Cipro XR, ciprofloxacin, ciprofloxacin extended release, Circavite T, Cit Calcium (obsolete), Citracal, Citracal Liquitab, Citracal Plus with Magnesium, Citracal Prenatal + DHA, Citracal Prenatal 90+DHA, Citracal Prenatal Rx, CitraNatal 90 DHA, CitraNatal DHA, CitraNatal Rx, Climara, Climaval, Climodien, Clinagen LA 40, Clusimar, colesevelam, Compete, Complete A-Z, Concentrated Phillips Milk of Magnesia, Conison, conjugated estrogens, conjugated estrogens synthetic A, conjugated estrogens synthetic B, conjugated estrogens topical, Contrin, Corvite, Corvite 150, Corvite Free, Coumadin, Crixivan, Daily Combo, Daily Multi-Vitamins with Minerals, Daily-Vite Weight Control, danazol, Danocrine, Dayalets Plus Iron, ddI, Deca-Durabolin, Decagen, Delatest, Delatestryl, Delestrogen, DELIDOSE, Dep Gynogen, Depandro 100, Depo-Estradiol, Depo-Testosterone, Depogen, Depotest, DermaVite, Dermestril, Dermestril - Septem, DERMESTRIL SEPTEM, Di-Phen, DiaBeta, Diabinese, Dialume, Dialyvite, Dialyvite 3000, Dialyvite 800 with Zinc, Dialyvite with Zinc Rx, Diatx Fe, Diatx Zn, Diavite Plus, Dicarbosil, dicumarol, didanosine, didanosine delayed release capsule, dienestrol topical, diethylstilbestrol, Digitek, digitoxin, digoxin, digoxin capsule, dihydroxyaluminum sodium carbonate, Dilantin, Dilantin Infatabs, Dilantin Kapseals, Dilantin-125, Dioval 40, Dioval XX, Disney Winnie the Pooh Complete, Disney Winnie the Pooh Gummies, Disney Winnie the Pooh with Extra C, Divigel 0.25 mg/packet, Divigel 0.5 mg/packet, Divigel 1 mg/packet, Dolomite, Dualvit OB, Duet, Duet Chewable, Duet DHA, Duet DHA EC, Dura-Estrin, Durabolin, Durabolin 50, Duragen, Duratest, Durathate 200, Dymelor, Ecee Plus, Eldercaps, Eldertonic, Elemental Iron, Elemental Iron-90, Elestrin, Elixophyllin, Elleste Solo, Ellis Tonic Sherry, elon Matrix 5000 Complete, Embrex 600, Emcyt, Encora, Enjuvia, Epitol, Equetro, Equi-Natal Care, Equi-Natal M, Equi-Natal Plus, Equi-Natal Rx, Equi-Natal Z, Equi-Roca Plus, Equicyte Plus, Equilet, Equinatal 90, Esclim, esterified estrogens, Estinyl, Estra-C, Estra-V 40, Estrace, Estrace Vaginal Cream, Estraderm, Estraderm MX, Estraderm TTS, estradiol, estradiol acetate, estradiol benzoate, estradiol cypionate, ESTRADIOL G GAM, Estradiol Patch, estradiol topical, estradiol valerate, Estradot, Estradot 100, Estradot 37.5, Estradot 50, Estradot 75, Estragyn 5, Estragyn LA 5, estramustine, ESTRAPATCH, Estrasorb, ESTREVA, Estring, Estro-A, Estro-Cyp, Estro-L.A., Estro-Span 40, Estrofem, Estrogel, estrone, Estrone AQ, estropipate, estropipate topical, ethinyl estradiol, Evamist, Everone, Evista, Evorel, Ex-Lax Milk of Magnesia, Extra Strength Mylanta Calci Tabs, EXUBERA, EXUBERA Combination Pack 12, EXUBERA Combination Pack 15, EXUBERA Kit, Fe 50, FE C Tab Plus, Fe-Tinic 150, Fe-Tinic 150 Forte, Fem-Natal, Fematrix, Femiron, Femiron Multi with Iron, Femnatal, Fempatch, Femring, FEMSEPT, FemSeven, FemSeven Sequi Phase I, FemTab, Femtabs, Femtrace, Femtran, Feocyte, Feogen, Feosol, Feosol Caplet, Feosol Iron, Feostat, Fer-Gen-Sol, Fer-in-Sol, Feratab, Ferate, Ferbee, Fergon, Fero-Folic 500, Fero-Gradumet Filmtab, Ferocon, FeroSul, Ferotrinsic, Ferra T.D. Caps, Ferra-Cap, Ferra-TD, Ferragen, Ferralet, Ferralet 90, Ferrets, Ferretts IPS, Ferrex PC Forte, Ferrex-150, Ferrex-150 Forte, Ferrimin 150, Ferro-Bob, Ferro-Time, Ferrocite, Ferrogels Forte, Ferrospace, ferrous fumarate, ferrous gluconate, ferrous gluconate extended release, ferrous sulfate, ferrous sulfate extended release, Ferus Pic-150, Fetrin, First Testosterone, FIRST-Testosterone, FIRST-Testosterone MC, Flintstones Complete, Flintstones with Calcium, Flintstones with Iron Chewable, fluoxymesterone, Folbee Plus CZ, Folgard OS, FoliTab 500, Folpace Rx, Foltabs, Foltrin, Formula B Plus, Formula Twenty-One, Fortamet, Fosfree, Fosrenol, Fruity Chews with Iron, Fumasorb, Fumatinic, Garfield Complete Vitamins, Garfield Vitamin with Iron, Generet-500 with Folic Acid, Generix-T, Geravim, Geri-Tabs, Geri-Tonic, Geritol, Geritol Complete, Geritol Extend, Gerivite Liquid, Gevrabon, Gevratonic, Gleevec, glimepiride, glipiZIDE, glipiZIDE extended release, GlipiZIDE XL, Glucophage, Glucophage XR, Glucotrol, Glucotrol XL, Glumetza, Glutofac-MX, Glutofac-ZX, glyBURIDE, glyBURIDE micronized, Glynase PresTab, Glyset, Gold Age Liquid Vitamins and Minerals, Gynodiol, Gynogen LA 20, Gynovite, Hair Booster, Halotestin, Hematinic Plus, Hematogen, Hematogen FA, Hematogen Forte, Hemax, heme iron polypeptide, Hemocyte, Hemocyte Plus, Hemocyte Plus (obsolete), Hemocyte-F Elixir, Hi-Nate 90, High Potency, Histerone, Humalog, Humalog Cartridge, Humalog KwikPen, Humalog Pen, Humulin L, Humulin N, Humulin N Pen, Humulin R, Humulin R (Concentrated), Humulin U, Hybolin Decanoate, Hybolin-Improved, Hytinic, I-L-X, I-L-X and B12, I-Sense, I-Sense OccuShield, I-Vite, I-Vite Protect, IBC 500, Iberet, Iberet Liquid, Iberet-500, Iberet-Folic-500, Icaps, ICaps AREDS, ICaps MV, ICaps Plus, Icaps TR, ICaps with Lutein and Zeaxan, Icar, Icar Prenatal, Icar Prenatal Chewable Calcium, Icar-C Plus, Icar-C Plus SR, Icare Prenatal Rx, Iferex 150 Forte, Iletin II Lente Pork, Iletin II NPH Pork, Iletin II Regular Pork, Iletin Lente, Iletin NPH, Iletin Regular, imatinib, Inatal Advance, Inatal Ultra, indinavir, insulin, insulin analog, insulin aspart, insulin aspart protamine, insulin detemir, insulin glargine, insulin glulisine, insulin inhalation, rapid acting, insulin isophane, Insulin Lente Pork, insulin lispro, insulin lispro protamine, Insulin Purified NPH Pork, Insulin Purified Regular Pork, insulin regular, insulin zinc, insulin zinc extended, insulin, lente, insulin, NPH, insulin, ultralente, Intrinsitinic, Iodotope, Ircon, Irofol, Iromin G, Iron Chews, iron polysaccharide, iron protein succinylate, Jantoven, Januvia, Kayexalate, Kestrone 5, Kionex, L-Tonic, Lactocal-F, Lanoxicaps, Lanoxin, lanthanum carbonate, Lantus, Lantus OptiClik Cartridge, Lantus Solostar Pen, Lente insulin, Levemir, Levemir FlexPen, Levemir InnoLet, Levemir PenFill, Livitrinsic-F, Losospan, Lowsium, Luminal, Lydia E. Pinkham, M-Vit, Maalox Antacid Barrier, Maalox Childrens', Maalox Quick Dissolve, Maalox Quick Dissolve Extra Strength, Maalox Quick Dissolve Maximum Strength, Maalox Regular Strength, Mag-SR with Calcium, magaldrate, Magna-C-7 Forte, MagneBind 400 Rx, magnesium hydroxide, Magonate Tablets, Maoson, Marnatal-F Plus, Martinic, Materna, Maternal 90, Maternity, Maternity plus Beta Carotene, Maternity Vitamin Low Iron, Maternity-90, Maxaron Forte, Maxinate, Mebaral, Medidiol 10, Mediplex Ultra, Meditest, Menaval-20, Menest, MENOREST, Menorest Patch, Menostar, Mens Pack, mephobarbital, mestranol, metformin, metformin extended release, methimazole, Methitest, methylTESTOSTERone, Mg hydroxide, Mi-C-T, Micronase, miglitol, Milk of Magnesia, Miradon, Mission Prenatal, Mission Prenatal FA, Mission Prenatal HP, Mission Prenatal Rx, Mol-Iron, Mult-Ferr Folic, Multi Vita Bets and Fluoride and Iron, Multi-betic, Multi-Day Plus Minerals, Multi-Day with Calcium and Extra Iron, Multi-Delyn with Iron, Multibret Folic 500, Multifol, Multifol Plus, Multilex, Multilex-T/M+Minerals, Multiret Folic 500, multivitamin with iron, multivitamin with iron and fluoride, multivitamin with minerals, multivitamin, prenatal, My-A-Multi, Myadec, Mycobutin, Myferon 150 Forte, MyKidz Iron, MyKidz Iron 10, MyKidz Iron FL, Mylanta Child, Mynatal, Mynatal FC, Mynatal Plus, Mynatal PN, Mynatal PN Forte, Mynatal Rx, Mynatal Ultracap, Mynatal Z, Mynate 90 Plus, Mysoline, Myvitalife, nandrolone, nandrolone decanoate, nandrolone phenpropionate, Natacaps, Natachew, Natafolic-OB, Natafolic-PN, Natafort, NatalCare, NatalCare Advanced, NatalCare Advanced-RF, NatalCare CFE 60, Natalcare Pic, Natalcare Pic Forte, Natalcare Plus, Natalcare Rx, NatalCare Three, Natalcare(obsolete), Natalfirst, Natalins, Natalins Rx, Natarex, Natatab CFe, Natatab FA, Natatab Rx, nateglinide, Natelle, Natelle C, Natelle Plus with DHA, Natelle Prefer, Natelle-ez, Neevo, Nembutal, Nembutal Sodium, Neo-Calglucon, Neo-Forte, Nephro Calci, Nephro-Fer, Nephro-Vite with Fe, Nephron-FA, Nestabs, Nestabs CBF, Nestabs FA, Nestabs Rx, New Advanced Formula Prenatal Z, NIC 750, Nicomide, Niferex, Niferex Elixir, Niferex Gold, Niferex PN Forte, Niferex(obsolete), Niferex-150 (obsolete), Niferex-150 Forte, Niferex-150 Forte (obsolete), Niferex-150(obsolete), Niferex-PN, Norlac RX, Northyx, Norvir, Norvir Soft Gelatin, Novanatal, NovaStart, Novastart (obsolete), Novolin L, Novolin N, Novolin N Innolet, Novolin N PenFill, Novolin R, Novolin R Innolet, Novolin R PenFill, NovoLog, NovoLog FlexPen, NovoLog PenFill, NPH insulin, Nu-Iron, Nu-Iron 150, Nu-Iron Plus, Nu-Iron V, NutriNate, Nutrispire, Nuvelle TS Phase I, O-CAL F.A., O-Cal Prenatal, O-Cal-FA, OB Complete, OB Complete with DHA, Ob-20, Obegyn, Obnate 90, Obtrex, Occuplex, Ocuvite, Ocuvite Extra, Ocuvite Lutein, Ocuvite PreserVision, Oesclim, Oestradiol, Oestradiol Implants, OESTRODOSE, OESTROGEL, Oestrogel Pump-Pack, Ogen 0.625, Ogen 1.25, Ogen 2.5, Ogen Vaginal Cream, One Daily with Minerals, One Tab Daily with Iron, One Tab Daily with Minerals, One-A-Day Max, One-A-Day Men 50 Plus, One-A-Day WeightSmart, One-A-Day Women, One-A-Day Women 50 Plus, Opti-Gen, Optilets-M-500, OptiNate, Optivite P.M.T., Oreton Methyl, Organon Oestradiol, Orinase, OROMONE, Ortho Dienestrol, Ortho-Est, Os-Cal, Os-Cal 500, Os-Cal Forte, Os-Cal Ultra, Ostiva, Oxandrin, oxandrolone, oxtriphylline, oxtriphylline extended release, Oysco 500, Oyst Cal, Oyst Cal 500, Oyster, Oyster Cal, Oyster Cal 500, Oyster Calcium, Oyster Shell, oyster shell calcium, Oyster Shell Calcium 500, Pan OB Forte, Par-F, pentobarbital, Pepto Children's, phenobarbital, Phenytek, phenytoin, phenytoin extended release, Phenytoin Sodium, Prompt, Phillips Milk of Magnesia, PhosLo, PhosLo Gelcap, PMS Balance, Poly Iron, Poly Iron Forte, Poly Vitamin with Fluoride with Iron, Poly-Vi-Flor with Iron, Poly-Vi-Sol with Iron, Poly-Vi-Sol with Iron Drops, Polysaccharide Iron, Posture, Pramilet FA, Prandin, Pre-H-Cal, Precare, Precare Conceive, Precare Premier, Precose, PreferaOB, Premarin, Premarin Intravenous, Premarin Vaginal, Premesis Rx, PrenaFirst, Prenatabs CBF, Prenatabs FA, Prenatabs OBN, Prenatabs Rx, Prenatal 1 Plus 1, Prenatal 1 Plus 1 (Low Iron), Prenatal 19, Prenatal AD, Prenatal Elite, Prenatal H, Prenatal Low Iron, Prenatal MR 90, Prenatal MR 90 Fe, Prenatal MTR with Selenium, prenatal multivitamin, Prenatal Multivitamins, Prenatal Plus, Prenatal Plus Iron, Prenatal Plus with 27 mg Iron, Prenatal Plus with Beta-Carotene, Prenatal Rx, Prenatal Rx 1, Prenatal S, Prenatal Z Advanced Formula, Prenatal-U, Prenate 90, Prenate Advance, Prenate Advanced Formula, Prenate DHA, Prenate Elite, Prenate GT, Prenate Ultra, Prenavite, Prenavite FC, Prenavite PC, Prenazyme 1+1, Preterna, Prevalite, Priftin, PrimaCare, PrimaCare Advantage, Primacare One, primidone, Primogyn Depot, Procycle Multi Vitamin with Minerals, Proferrin-ES, Proferrin-Forte, Progynova, Progynova TS, Promar, Pronemia, propylthiouracil, Proquin XR, Prosight, protamine zinc insulin, Protegra Softgel, PROVAMES, Questran, Questran Light, Quibron-T, Quibron-T/SR, quinapril, quinestrol, raloxifene, Re Dualvit F, Re Dualvit Plus, RE Fac-X, regular insulin, ReliOn/Novolin N, ReliOn/Novolin R, RenaPlex, Renatabs with Iron, Renax, Renax 5.5, Reocyte Plus, repaglinide, Repliva 21/7, Resource Optisource, Respbid, Ri-Mag, Ridactate, rifabutin, Rifadin, Rifadin IV, rifampin, rifapentine, Rimactane, Riomet, Riopan, ritonavir, Rolaids Sodium Free, Rolaids Soft Chew, Ron Acid, Ru-Lets M 500, Sandrena, secobarbital, Seconal Sodium, Select-OB, Senetonic, Senilezol, Sesame St. Vitamins Complete, Sesame St. Vitamins Plus Iron, Siderol, Simron, sitagliptin, Slo-Bid Gyrocaps, Slo-Phyllin, Slo-Phyllin 125, Slo-Phyllin 80, Slow Fe, Slow Release Iron, sodium iodide-I-131, sodium polystyrene sulfonate, Solfoton, SourceCF Chewables, SourceCF Multivitamins with A,B,D,E & K plus Zinc, SourceCF Pediatric Drops, SourceCF Softgels, SSS, SSS Tonic, stanozolol, Starlix, Stilphostrol, Stress 600 with Zinc, Stress Formula with Iron, Stress Formula with Zinc, Stresstabs with Iron, StressTabs with Zinc, Striant, Strongstart, Strovite, Strovite Advance, Strovite Advance+D, Strovite Forte, Strovite Plus, Stuart Prenatal with Beta Carotene, Stuartnatal Plus, Stuartnatal Plus 3, Sunkist Child Chewable with Iron, Super Calcium, Super High Vitamins and Minerals, Support, Support 500, Surbex-750 with Iron, Surbex-750 with Zinc, Surpass, Surpass Extra Strength, SYSTEN, T-Gran plus Minerals, T-Lite, T-Phyl, Tab-A-Vite Maximum, Tab-A-Vite WeightSlim, Tab-A-Vite with Iron, Tab-A-Vite Womens Formula, Tace, Tandem DHA, Tandem OB, Tandem Plus, Tapazole, Tegretol, Tegretol XR, Ternamar, Teslac, Testamone-100, Testim, Testim 5 g/packet, Testoderm, testolactone, Testolin, Testopel Pellets, testosterone, Testosterone Cypionate, Testosterone Enanthate, testosterone propionate, testosterone topical, Testred, Testro, Testro AQ, Testro-L.A., THAIS, THAISSEPT, Theo-24, Theo-Dur, Theo-Dur Sprinkles, Theo-Time, Theo-X, Theobid, TheoCap, Theochron, Theoclear L.A.-130, Theoclear L.A.-260, Theoclear-80, Theolair, Theolair-SR, theophylline, theophylline 24 hr extended release, theophylline extended release, Theovent, Thera Hematinic, Thera M, Thera-M, Thera-Vite M, Theragener-H, Theragener-M, Theragran Hematinic, Theragran-M, Therapeutic-M, Theravim M, Therems H, Therems M, Therobec Plus, Titralac, Tol-Tab, TOLAZamide, TOLBUTamide, Tolfrinic, Tolinase, Tri Vites with Fluoride and Iron, Tri-Vi-Flor with Iron, Tri-Vi-Sol with Iron, tricalcium phosphate, TriCare, Tricon, TriHEMIC 600, Trinate, Trinsicon, Truphylline, Truxophyllin, Tums, Tums 500, Tums E-X, Tums Extra Strength, Tums Ultra, Udamin, Udamin SP, Ultra Mylanta Calci Tabs, Ultra NatalCare, Ultra-Natal, Ultralente insulin, Uni Kar Plus C SR, Uni-Daily Plus Iron, Uni-Dur, Uni-Fac ZX, Uni-Thera M with Beta Carotene, Unicap M, Unicap Senior, Unicap T, Unicap with Iron, Unicomplex M, Uniphyl, V-C Forte, Vagifem, Valergen, Velosulin BR, Vernate, Vernate Advanced, Verotin-BY, Verotin-GR, Vi-Daylin ADC with Iron, Vi-Daylin with Iron, Vi-Daylin with Iron Chewable, Vi-Daylin with Iron Drops, Vi-Daylin/F ADC with Iron, Vi-Daylin/F Plus Iron, Vi-Stress with Iron, Vi-Zac, Viactiv Calcium Flavor Glides, Viactiv Multi-Vitamin, Viactiv Multi-Vitamin Flavor Glides, Viactiv Soft Calcium Chews, Vica-Forte, Vicap Forte, Vicon Forte, Vicon Plus, Vicon-C, Videx, Videx EC, Vigortol Liquid, Vimar with Iron, Vinatal 600, Vinatal Forte, Vinate 90, Vinate Advanced (New Formula), Vinate AZ, Vinate AZ Extra, Vinate Calcium, Vinate Good Start, Vinate GT, Vinate II (New Formula), Vinate M, Vinate Ultra, Viogen-C, Virilon, Virilon IM, Vita Drops with Iron, Vita S Forte, Vita Zx, Vita-Dec, Vita-Min Rx, Vita-PMS, Vita-PMS Plus, Vita-Zinc, Vitacon Forte, Vitafol, Vitafol PN, Vitafol-OB, Vitafol-OB+DHA, Vital-D, Vitalize Plus, Vitamax, Vitamed Prenatal Formula, Vitaphil, Vitaplex Plus, Vitelle Nestabs OTC, Vivelle, Vivelle-Dot, VIVELLEDOT, Vynatal 1 Plus 1, Vynatal F.A., warfarin, Welchol, Winstrol, Womens Pack, Yieronia, Z-Bec, Z-Gen, ZE-Plus, Zenate, Zenate Advanced Formula, Zenate Prenatal, Zinc with Vitamin C, Zincvit, Zitamin, Zodeac-100, Zumenon

Minor Interactions
acebutolol, Adapin, Altocor, Altoprev, amitriptyline, amoxapine, Anafranil, Asendin, atenolol, Aventyl HCl, Betapace, Betapace AF, Betapace AF(obsolete), betaxolol, bisoprolol, Blocadren, Brevibloc, Carafate, carteolol, Cartrol, carvedilol, carvedilol extended release, cimetidine, clomiPRAMINE, Coreg, Coreg CR, Corgard, desipramine, Desyrel, Desyrel Dividose, doxepin, doxepin topical, Elavil, Endep, esmolol, fluoxetine, fluoxetine extended release, imipramine, imipramine pamoate, Inderal, Inderal LA, InnoPran XL, Kerlone, labetalol, Levatol, Lopressor, lovastatin, lovastatin extended release, metipranolol ophthalmic, metoprolol, metoprolol extended release, metoprolol succinate, Metoprolol Succinate ER, metoprolol tartrate, Mevacor, nadolol, Normodyne, Norpramin, nortriptyline, OptiPranolol, Pamelor, penbutolol, pindolol, propranolol, propranolol extended release, protriptyline, Prozac, Prozac Weekly, Prudoxin, Rapiflux, Sarafem, Sectral, Selfemra, simvastatin, Sinequan, Sorine, sotalol, Sotalol Hydrochloride AF, Sotalol Hydrochloride AF(obsolete), sucralfate, Surmontil, Tagamet, Tagamet HB, Tenormin, timolol, Tofranil, Tofranil-PM, Toprol-XL, Trandate, traZODONE, trimipramine, Vanatrip, Visken, Vivactil, Zebeta, Zocor, Zonalon