Tetralogy of fallot epidemiology and demographics


 * Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [mailto:psingh@perfuse.org], Keri Shafer, M.D. [mailto:kshafer@bidmc.harvard.edu];  Assistant Editor-In-Chief: Kristin Feeney, B.S. [mailto:kfeeney@perfuse.org]

Overview
Tetralogy of Fallot represents 5-7% of congenital heart defects. Tetralogy of Fallot is the most common cause of cyanotic heart disease and accounts for one third of all cases of cyanotic heart disease.

Epidemiology and demographics

 * Tetralogy of Fallot occurs in approximately 3 to 6 per 10,000 births
 * It represents 5-7% of congenital heart defects.

Genetics

 * The majority of cases are thought to be sporadic and are not familial.
 * The incidence in siblings is 1% to 5%.

Sex

 * Tetralogy of Fallot occurs slightly more often in males than in females.