Sulbutiamine

Overview
Sulbutiamine (brand name: Arcalion&reg;) is a precursor to thiamine (i.e., vitamin B1). It is indicated for the treatment of asthenia. Furthermore, the ability of sulbutiamine to reduce fatigue is considered desirable by athletes, and it is available for over-the-counter sale as a nutritional supplement. Additionally, the demonstrated ability of sulbutiamine to improve memory in rats and patients of schizophrenia suggests that it is a nootropic.

Effects
Sulbutiamine reduces fatigue, memory difficulties, intellectual tiredness and may speed convalescence.

Dosage
Sulbutiamine is sometimes supplied in 200 mg tablets. The proper therapeutic dosage has been reported to be 12.5 mg/kg, which corresponds to 850 mg for a 68 kg (150 lb) person. However, it should be noted that dosage recommendations vary; the manufacturer of Arcalion, for example, recommends no more than 600 mg per day.