Enterovirus 5' cloverleaf cis-acting replication element

The Enterovirus 5' cloverleaf cis-acting replication element is an RNA element found in the 5' UTR of Enterovirus genomes. The element has a cloverleaf like secondary structure and is known to be a multifunctional cis-acting replication element (CRE), required for the initiation of negative strand RNA synthesis.