Abciximab contraindications

Contraindications
Because Abciximab may increase the risk of bleeding, Abciximab is contraindicated in the following clinical situations:
 * Active internal bleeding
 * Recent (within six weeks) gastrointestinal (GI) or genitourinary (GU) bleeding of clinical significance.
 * History of cerebrovascular accident (CVA) within two years, or CVA with a significant residual neurological deficit
 * Bleeding diathesis
 * Administration of oral anticoagulants within seven days unless prothrombin time is <1.2 times control
 * Thrombocytopenia (<100 000 cells/m L)
 * Recent (within six weeks) major surgery or trauma
 * Intracranial neoplasm, arteriovenous malformation, or aneurysm
 * Severe uncontrolled hypertension
 * Presumed or documented history of vasculitis
 * Use of intravenous dextran before PCI, or intent to use it during an intervention
 * Abciximab is also contraindicated in patients with known hypersensitivity to any component of this product or to murine proteins.