Phenylpyruvate tautomerase

In enzymology, a phenylpyruvate tautomerase is an enzyme that catalyzes the chemical reaction


 * keto-phenylpyruvate $$\rightleftharpoons$$ enol-phenylpyruvate

Hence, this enzyme has one substrate, keto-phenylpyruvate, and one product, enol-phenylpyruvate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting keto- and enol-groups. The systematic name of this enzyme class is phenylpyruvate keto---enol-isomerase. This enzyme is also called phenylpyruvic keto-enol isomerase. This enzyme participates in tyrosine metabolism and phenylalanine metabolism.

Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , and.