Cobaltochelatase

In enzymology, a cobaltochelatase is an enzyme that catalyzes the chemical reaction


 * ATP + hydrogenobyrinic acid a,c-diamide + Co2+ + H2O $$\rightleftharpoons$$ ADP + phosphate + cob(II)yrinic acid a,c-diamide + H+

The 4 substrates of this enzyme are ATP, hydrogenobyrinic acid a,c-diamide, Co2+, and H2O, whereas its 4 products are ADP, phosphate, cob(II)yrinic acid a,c-diamide, and H+.

This enzyme belongs to the family of ligases, specifically those forming nitrogen-D-metal bonds in coordination complexes. The systematic name of this enzyme class is hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming). Other names in common use include hydrogenobyrinic acid a,c-diamide cobaltochelatase, CobNST, and CobNCobST. This enzyme participates in porphyrin and chlorophyll metabolism.