Seronegative spondyloarthritis

Overview
"Seronegative" refers to the fact that these diseases are negative for Rheumatoid factor and CCP in the serum.

Seronegative spondyloarthritis is a group of diseases, including:


 * psoriatic arthritis
 * Reiter's disease
 * arthritis in association with inflammatory bowel disease
 * ankylosing spondylitis
 * Behcet's syndrome
 * Whipple's disease

These diseases has following conditions in common:
 * They are in relation to HLA-B27
 * sacroiliitis and spondylitis are present in them.
 * familial aggregation occurs
 * Overlap is likely in them
 * rheumatoid factor is not present