Allophanate hydrolase

In enzymology, an allophanate hydrolase is an enzyme that catalyzes the chemical reaction


 * urea-1-carboxylate + H2O $$\rightleftharpoons$$ 2 CO2 + 2 NH3

Thus, the two substrates of this enzyme are urea-1-carboxylate and H2O, whereas its two products are CO2 and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is urea-1-carboxylate amidohydrolase. This enzyme is also called allophanate lyase. This enzyme participates in urea cycle and metabolism of amino groups and atrazine degradation.