Anti-cholesterol

Anti-cholesterol is a naturally-occurring antibody to cholesterol produced by mammals. It is believed that this antibody serves a ‘housekeeping’ or protective role for the host animal, helping to protect the animal from harmful forms of cholesterol such as LDL and VLDL.

Modes of Action
An immunoglobulin protein, anti-cholesterol may be found both in circulation as well as in the digestive tract.


 * In circulation, this antibody binds selectively to the small, dense, oxidized cholesterol-rich LDL particles that are known to contribute to the development of atherosclerosis. The antibody does not bind the good forms of cholesterol such as HDL.


 * In the gastrointestinal tract, the antibody acts as a cholesterol absorption inhibitor. The antibody selectively binds to cholesterol-rich micelles  and prevents their uptake by the intestinal enterocyte.  The antibody-bound micelle is then removed through fecal clearance.