CDP-glucose 4,6-dehydratase

In enzymology, a CDP-glucose 4,6-dehydratase is an enzyme that catalyzes the chemical reaction


 * CDP-glucose $$\rightleftharpoons$$ CDP-4-dehydro-6-deoxy-D-glucose + H2O

Hence, this enzyme has one substrate, CDP-glucose, and two products, CDP-4-dehydro-6-deoxy-D-glucose and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include cytidine diphosphoglucose oxidoreductase, and CDP-glucose 4,6-hydro-lyase. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.