Metabolic network

A metabolic network is the complete set of metabolic and physical processes that determine the physiological and biochemical properties of a cell. As such, these networks comprise the chemical reactions of metabolism as well as the regulatory interactions that guide these reactions.

With the sequencing of complete genomes, it is now possible to reconstruct the network of biochemical reactions in many organisms, from bacteria to human. Several of these networks are available online: Kyoto Encyclopedia of Genes and Genomes (KEGG), EcoCyc and BioCyc. Metabolic networks are powerful tools, for studying and modelling metabolism. From the study of metabolic networks' topology with graph theory to predictive toxicology and ADME.