Glycine formimidoyltransferase

In enzymology, a glycine formimidoyltransferase is an enzyme that catalyzes the chemical reaction


 * 5-formimidoyltetrahydrofolate + glycine $$\rightleftharpoons$$ tetrahydrofolate + N-formimidoylglycine

Thus, the two substrates of this enzyme are 5-formimidoyltetrahydrofolate and glycine, whereas its two products are tetrahydrofolate and N-formimidoylglycine.

This enzyme belongs to the family of transferases that transfer one-carbon groups, specifically the hydroxymethyl-, formyl- and related transferases. The systematic name of this enzyme class is 5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase. Other names in common use include formiminoglycine formiminotransferase, FIG formiminotransferase, and glycine formiminotransferase. This enzyme participates in purine metabolism and one carbon pool by folate.