Late congenital syphilis

Late congenital syphilis is a subset of cases of congenital syphilis. By definition, it occurs in children at or greater that 2 years of age who acquired the infection trans-placentally.

Symptoms include
 * blunted upper incisor teeth known as Hutchinson's teeth
 * inflammation of the cornea known as interstitial keratitis
 * deafness from auditory nerve disease
 * frontal bossing (prominence of the brow ridge)
 * saddle nose (collapse of the bony part of nose)
 * hard pallet defect
 * swollen knees
 * saber shins
 * short maxillae
 * protruding mandible

A frequently-found group of symptoms is Hutchinson's triad, which consists of Hutchinson's teeth (notched incisors), keratitis and deafness and occurs in 63% of cases.

Treatment (with penicillin) before the development of late symptoms is essential.