Unstable angina / non ST elevation myocardial infarction long-term medical therapy and secondary prevention ACC/AHA guidelines nonsteroidal anti-inflammatory drugs


 * Associate Editors-in-Chief: Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S.

==ACC / AHA Guidelines - Nonsteroidal Anti-Inflammatory Drugs(DO NOT EDIT) ==

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Class I
1. At the time of preparation for hospital discharge, the patient’s need for treatment of chronic musculoskeletal discomfort should be assessed, and a stepped-care approach to treatment should be used for selection of treatments. Pain relief should begin with acetaminophen, small doses of narcotics, or non acetylated salicylates. (Level of Evidence: C)

Class IIa
1. It is reasonable to use nonselective NSAIDs, such as naproxen, if initial therapy with acetaminophen, small doses of narcotics, or non acetylated salicylates is insufficient. (Level of Evidence: C)

Class IIb
1. Non steroidal anti inflammatory drugs with increasing degrees of relative COX-2 selectivity may be considered for pain relief only for situations in which intolerable discomfort persists despite attempts at stepped-care therapy with acetaminophen, small doses of narcotics, non acetylated salicylates, or non selective NSAIDs. In all cases, the lowest effective doses should be used for the shortest possible time. (Level of Evidence: C)

Class III
1. Non steroidal anti inflammatory drugs with increasing degrees of relative COX-2 selectivity should not be administered to UA / NSTEMI patients with chronic musculoskeletal discomfort when therapy with acetaminophen, small doses of narcotics, non acetylated salicylates, or non selective NSAIDs provides acceptable levels of pain relief. (Level of Evidence: C)}}