The Living Guidelines: Chronic Stable Angina Pectoris Recommendations for LDL-C, HDL-C and Triglycerides Management Suggest Revisions to the CLASS IIa Guidelines

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Class IIa Guidelines
1- Reduction of LDL-C to <70 mg/dL or high-dose statin therapy is reasonable. (Class IIa Level of Evidence: A)

2- If baseline LDL-C is 70-100 mg/dL, it is reasonable to treat LDL-C to <70 mg/dL. (Class IIa Level of Evidence: B)

3- Therapeutic options to reduce non–HDL-C are:


 * Niacin can be useful as a therapeutic option to reduce non-HDL-C (after LDL-C lowering therapy) (Class IIa Level of Evidence: B)

or


 * Fibrate therapy as a therapeutic option can be useful to reduce non-HDL-C (after LDL-C lowering therapy). (Class IIa Level of Evidence: B)

4- Further reduction of non-HDL-C to <100 mg/dL is reasonable, if Triglycerides are ≥200 to 499 mg/dL. (Class IIa Level of Evidence: B)