Initiator motif

The Initiatior (Inr) motif is a DNA transcription promoter that is similar in function to the Pribnow box (for prokaryotes) or the TATA box (for eukaryotes). It has the consensus sequence YYAN(T/A)YY, where Y stands for any pyrimidine (cytosine or thymine). Similarly to the TATA box, the Inr motif facilitates the binding of Transcription Factor II D (TBP).