(citrate (pro-3S)-lyase) ligase

In enzymology, a [citrate (pro-3S)-lyase] ligase is an enzyme that catalyzes the chemical reaction


 * ATP + acetate + [citrate (pro-3S)-lyase](thiol form) $$\rightleftharpoons$$ AMP + diphosphate + [citrate (pro-3S)-lyase](acetyl form)

The 3 substrates of this enzyme are ATP, acetate, and [citrate (pro-3S)-lyase](thiol form), whereas its 3 products are AMP, diphosphate, and [citrate (pro-3S)-lyase](acetyl form).

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is acetate:[citrate-(pro-3S)-lyase](thiol-form) ligase (AMP-forming). Other names in common use include citrate lyase ligase, citrate lyase synthetase, acetate: SH-[acyl-carrier-protein] enzyme ligase (AMP), acetate:HS-citrate lyase ligase, and acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming). This enzyme participates in two-component system - general.