Quinate dehydrogenase (pyrroloquinoline-quinone)

In enzymology, a quinate dehydrogenase (pyrroloquinoline-quinone) is an enzyme that catalyzes the chemical reaction


 * quinate + pyrroloquinoline-quinone $$\rightleftharpoons$$ 3-dehydroquinate + reduced pyrroloquinoline-quinone

Thus, the two substrates of this enzyme are quinate and pyrroloquinoline-quinone, whereas its two products are 3-dehydroquinate and reduced pyrroloquinoline-quinone.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is quinate:pyrroloquinoline-quinone 3-oxidoreductase. Other names in common use include NAD(P)+-independent quinate dehydrogenase, and quinate:pyrroloquinoline-quinone 5-oxidoreductase. This enzyme participates in phenylalanine, tyrosine and tryptophan biosynthesis.