Primary sclerosing cholangitis overview

Overview
Primary sclerosing cholangitis (PSC) is a form of cholangitis due to an autoimmune reaction. A cholangitis is aninflammation of the bile ducts of the liver. Primary sclerosing cholangitis leads to cholestasis (blockage of biletransport to the gut). Blockage of the bile duct leads to accumulation of bile, which damages the liver, leading to jaundice and eventually causes liver failure.