Balding-Nichols Model

The Balding-Nichols model is a statistical description of the allele frequencies in the components of a sub-divided population. With background allele frequency $$p$$ the allele frequencies in sub-populations separated by Wright's $$F_{st}$$ $$F$$ are distributed according to independent draws from


 * $$B\left(\frac{1-F}{F}p,\frac{1-F}{F}(1-p)\right)$$

where $$B$$ is the Beta distribution

The model is due to David Balding and Richard Nichols and is widely used in the forensic analysis of DNA profiles.