Buspirone drug interactions

List of drug interactions
Psychotropic agents Inhibitors and inducers of cytochrome P450 3A4 (CYP3A4) Other drugs Protein binding Drug/laboratory test interactions
 * MAO inhibitors
 * Amitriptyline
 * Diazepam
 * Haloperidol
 * Nefazodone
 * Trazodone
 * Triazolam/flurazepam
 * Other psychotropics
 * Diltiazem and verapamil
 * Erythromycin
 * Grapefruit juice
 * Itraconazole
 * Nefazodone
 * Manifestations
 * Rifampin
 * Other inhibitors and inducers of CYP3A4
 * Cimetidine

MAO inhibitors
It is recommended that BuSpar not be used concomitantly with MAO inhibitors. Return to top

Amitriptyline
After addition of buspirone to the amitriptyline dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) of amitriptyline or its metabolite nortriptyline were observed. Return to top

Diazepam
After addition of buspirone to the diazepam dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) were observed for diazepam, but increases of about 15% were seen for nordiazepam, and minor adverse clinical effects (dizziness, headache, and nausea) were observed. Return to top

Haloperidol
In a study in normal volunteers, concomitant administration of buspirone and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear. Return to top

Nefazodone
(see Inhibitors and inducers of cytochrome P450 3A4 [CYP3A4]) Return to top

Trazodone
There is one report suggesting that the concomitant use of Desyrel® (trazodone hydrochloride) and buspirone may have caused 3- to 6-fold elevations on SGPT (ALT) in a few patients. In a similar study attempting to replicate this finding, no interactive effect on hepatic transaminases was identified. Return to top

Triazolam/flurazepam
Coadministration of buspirone with either triazolam or flurazepam did not appear to prolong or intensify the sedative effects of either benzodiazepine. Return to top

Other psychotropics
Because the effects of concomitant administration of buspirone with most other psychotropic drugs have not been studied, the concomitant use of buspirone with other CNS-active drugs should be approached with caution. Return to top

Inhibitors and inducers of cytochrome P450 3A4 (CYP3A4)
Buspirone has been shown in vitro to be metabolized by CYP3A4. This finding is consistent with the in vivo interactions observed between buspirone and the following: Return to top

Diltiazem and verapamil
In a study of nine healthy volunteers, coadministration of buspirone (10 mg as a single dose) with verapamil (80 mg t.i.d.) or diltiazem (60 mg t.i.d.) increased plasma buspirone concentrations (verapamil increased AUC and Cmax of buspirone 3.4-fold while diltiazem increased AUC and Cmax 5.5-fold and 4-fold, respectively.) Adverse events attributable to buspirone may be more likely during concomitant administration with either diltiazem or verapamil. Subsequent dose adjustment may be necessary and should be based on clinical assessment. Return to top

Erythromycin
In a study in healthy volunteers, coadministration of buspirone (10 mg as a single dose) with erythromycin (1.5 g/day for 4 days) increased plasma buspirone concentrations (5-fold increase in Cmax and 6-fold increase in AUC). These pharmacokinetic interactions were accompanied by an increased incidence of side effects attributable to buspirone. If the two drugs are to be used in combination, a low dose of buspirone (eg, 2.5 mg b.i.d.) is recommended. Subsequent dose adjustment of either drug should be based on clinical assessment. Return to top

Grapefruit juice
In a study in healthy volunteers, coadministration of buspirone (10 mg as a single dose) with grapefruit juice (200 mL double-strength t.i.d. for 2 days) increased plasma buspirone concentrations (4.3-fold increase in Cmax; 9.2-fold increase in AUC). Patients receiving buspirone should be advised to avoid drinking such large amounts of grapefruit juice. Return to top

Itraconazole
In a study in healthy volunteers, coadministration of buspirone (10 mg as a single dose) with itraconazole (200 mg/day for 4 days) increased plasma buspirone concentrations (13-fold increase in Cmax and 19-fold increase in AUC). These pharmacokinetic interactions were accompanied by an increased incidence of side effects attributable to buspirone. If the two drugs are to be used in combination, a low dose of buspirone (eg, 2.5 mg q.d.) is recommended. Subsequent dose adjustment of either drug should be based on clinical assessment. Return to top

Nefazodone
In a study of steady-state pharmacokinetics in healthy volunteers, coadministration of buspirone (2.5 or 5 mg b.i.d.) with nefazodone (250 mg b.i.d.) resulted in marked increases in plasma buspirone concentrations (increases up to 20-fold in Cmax and up to 50-fold in AUC) and statistically significant decreases (about 50%) in plasma concentrations of the buspirone metabolite 1-PP. With 5 mg b.i.d. doses of buspirone, slight increases in AUC were observed for nefazodone (23%) and its metabolites hydroxynefazodone (HO-NEF) (17%) and meta-chlorophenylpiperazine (9%). Slight increases in Cmax were observed for nefazodone (8%) and its metabolite HO-NEF (11%). Return to top

Manifestations
Subjects receiving buspirone 5 mg b.i.d. and nefazodone 250 mg b.i.d experienced lightheadedness, asthenia, dizziness, and somnolence, adverse events also observed with either drug alone. If the two drugs are to be used in combination, a low dose of buspirone (eg, 2.5 mg q.d.) is recommended. Subsequent dose adjustment of either drug should be based on clinical assessment. Return to top

Rifampin
In a study in healthy volunteers, coadministration of buspirone (30 mg as a single dose) with rifampin (600 mg/day for 5 days) decreased the plasma concentrations (83.7% decrease in Cmax; 89.6% decrease in AUC) and pharmacodynamic effects of buspirone. If the two drugs are to be used in combination, the dosage of buspirone may need adjusting to maintain anxiolytic effect. Return to top

Other inhibitors and inducers of CYP3A4
Substances that inhibit CYP3A4, such as ketoconazole or ritonavir, may inhibit buspirone metabolism and increase plasma concentrations of buspirone while substances that induce CYP3A4, such as dexamethasone or certain anticonvulsants (phenytoin, phenobarbital, carbamazepine), may increase the rate of buspirone metabolism. If a patient has been titrated to a stable dosage on buspirone, a dose adjustment of buspirone may be necessary to avoid adverse events attributable to buspirone or diminished anxiolytic activity. Consequently, when administered with a potent inhibitor of CYP3A4, a low dose of buspirone used cautiously is recommended. When used in combination with a potent inducer of CYP3A4 the dosage of buspirone may need adjusting to maintain anxiolytic effect. Return to top

Cimetidine
Coadministration of buspirone with cimetidine was found to increase Cmax (40%) and Tmax (2–fold), but had minimal effects on the AUC of buspirone. Return to top

Protein binding
In vitro, buspirone does not displace tightly bound drugs like phenytoin, propranolol, and warfarin from serum proteins. However, there has been one report of prolonged prothrombin time when buspirone was added to the regimen of a patient treated with warfarin. The patient was also chronically receiving phenytoin, phenobarbital, digoxin, and Synthroid®. In vitro, buspirone may displace less firmly bound drugs like digoxin. The clinical significance of this property is unknown. Therapeutic levels of aspirin, desipramine, diazepam, flurazepam, ibuprofen, propranolol, thioridazine, and tolbutamide had only a limited effect on the extent of binding of buspirone to plasma proteins. Return to top

Drug/laboratory test interactions
Buspirone is not known to interfere with commonly employed clinical laboratory tests. Return to top

Major Interactions

 * 5-HTP
 * 5-hydroxytryptophan
 * Adapin
 * amitriptyline
 * amoxapine
 * Anafranil
 * Asendin
 * Atapryl
 * Aventyl HCl
 * Azilect
 * Carbex
 * Celexa
 * citalopram
 * clomipramine
 * Cymbalta
 * Darvon
 * Darvon-N
 * desipramine
 * desvenlafaxine
 * Desyrel
 * Desyrel Dividose
 * dexfenfluramine
 * doxepin
 * doxepin topical
 * duloxetine
 * Effexor
 * Effexor XR
 * Elavil
 * Eldepryl
 * Emsam
 * Endep
 * escitalopram
 * fenfluramine
 * fluoxetine
 * fluoxetine extended release
 * fluvoxamine
 * fluvoxamine extended release
 * furazolidone
 * Furoxone
 * GHB
 * hypericum perforatum
 * imipramine
 * imipramine pamoate
 * isocarboxazid
 * Jumex
 * l-tryptophan
 * levomethadyl acetate
 * Lexapro
 * linezolid
 * Luvox
 * Luvox CR
 * Marplan
 * Matulane
 * Meridia
 * mirtazapine
 * Nardil
 * Norpramin
 * nortriptyline
 * Orlaam
 * Pamelor
 * Parnate
 * paroxetine
 * paroxetine extended release
 * paroxetine mesylate
 * Paxil
 * Paxil CR
 * Pexeva
 * phenelzine
 * Pondimin
 * PP-Cap
 * Pristiq
 * procarbazine
 * propoxyphene
 * propoxyphene hydrochloride
 * propoxyphene napsylate
 * protriptyline
 * Prozac
 * Prozac Weekly
 * Prudoxin
 * Rapiflux
 * rasagiline
 * Redux
 * Remeron
 * Remeron SolTab
 * Sarafem
 * selegiline
 * Selfemra
 * Selgene
 * sertraline
 * sibutramine
 * Sinequan
 * sodium oxybate
 * St. John's wort
 * Surmontil
 * Tofranil
 * Tofranil-PM
 * tranylcypromine
 * trazodone
 * trimipramine
 * Tryptan
 * tryptophan
 * Vanatrip
 * venlafaxine
 * venlafaxine extended release
 * Vivactil
 * Xyrem
 * Zelapar
 * Zoloft
 * Zonalon
 * Zyvox

Moderate Interactions

 * 40 Winks
 * Abilify
 * Abilify Discmelt
 * Accupril
 * acebutolol
 * Aceon
 * acetylcarbromal
 * Actiq
 * Adalat
 * Adalat CC
 * Adgan
 * Adrenocot
 * Adrenocot L.A.
 * Afeditab CR
 * Agenerase
 * AHist
 * Akineton HCl
 * alcohol
 * alcohol
 * ethyl
 * Aldactone
 * Aler-Dryl
 * Aler-Tab
 * Alfenta
 * alfentanil
 * alfuzosin
 * alfuzosin extended release
 * All Day Allergy
 * Aller-Chlor
 * Allergia-C
 * Allerhist-1
 * Allermax
 * Alphagan
 * Alphagan P
 * Altace
 * Altaryl
 * Ambien
 * Ambien CR
 * amiloride
 * aminoglutethimide
 * amlodipine
 * amobarbital
 * amprenavir
 * Amrix
 * amyl nitrite
 * Amytal Sodium
 * Anergan 50
 * Antiflex
 * Antinaus 50
 * Antivert
 * Anturane
 * APO-Go
 * APO-Go Pen
 * Apokyn
 * apomorphine
 * apraclonidine ophthalmic
 * aprepitant
 * Apresoline
 * Aquachloral Supprettes
 * Aquacot
 * Aquatensen
 * Aquazide H
 * Arfonad
 * aripiprazole
 * armodafinil
 * Artane
 * Astelin
 * Astramorph PF
 * Atacand
 * Atarax
 * atenolol
 * Avapro
 * Avinza
 * azatadine
 * azelastine nasal
 * B-Vex
 * baclofen
 * Banaril
 * Banflex
 * Banophen
 * Beldin
 * Belix
 * Ben-Tann
 * Benadryl
 * Benadryl Allergy
 * Benadryl Child Dye Free
 * Benadryl Childrens Allergy Fastmelt
 * Benadryl DF
 * Benadryl Dye Free Allergy
 * Benadryl Ultratab
 * Benahist-10
 * Benahist-50
 * benazepril
 * bendroflumethiazide
 * Benicar
 * Benoject-50
 * Benzacot
 * benzthiazide
 * benztropine
 * Betapace
 * Betapace AF
 * Betapace AF(obsolete)
 * betaxolol
 * Biaxin
 * Biaxin XL
 * Biaxin XL-Pak
 * Bidhist
 * biperiden
 * bisoprolol
 * Blocadren
 * Bonine
 * bosentan
 * Brevibloc
 * brimonidine ophthalmic
 * Bromaphen
 * bromocriptine
 * bromodiphenhydramine
 * brompheniramine
 * brompheniramine extended release
 * BroveX
 * BroveX CT
 * Bubbli-Pred
 * bumetanide
 * Bumex
 * Buprenex
 * buprenorphine
 * Busodium
 * butabarbital
 * butalbital
 * Butisol Sodium
 * butorphanol
 * butorphanol nasal
 * Bydramine
 * C.P.M.
 * Calan
 * Calan SR
 * Calm-Aid
 * candesartan
 * Capoten
 * captopril
 * Carbacot
 * carbamazepine
 * carbamazepine extended release
 * Carbatrol
 * carbetapentane
 * carbinoxamine
 * carbinoxamine extended release
 * Carbinoxamine PD
 * Carboxine
 * Cardene
 * Cardene IV
 * Cardene SR
 * Cardizem
 * Cardizem CD
 * Cardizem LA
 * Cardizem Monovial
 * Cardizem SR
 * Cardura
 * Cardura XL
 * Carduran
 * carisoprodol
 * Carozide
 * carteolol
 * Cartia XT
 * Cartrol
 * carvedilol
 * carvedilol extended release
 * Cascor
 * Catapres
 * Catapres-TTS-1
 * Catapres-TTS-2
 * Catapres-TTS-3
 * Celontin
 * Cerebyx
 * Cesamet
 * cetirizine
 * Chem Mart Tramadol
 * Chlo-Amine
 * Chlor-Al Rel
 * Chlor-Mal
 * Chlor-Phen
 * Chlor-Phenit
 * Chlor-Trimeton
 * Chlor-Trimeton Allergy SR
 * chloral hydrate
 * chlordiazepoxide
 * chlormezanone
 * chlorothiazide
 * Chlorphen
 * chlorphenesin
 * chlorpheniramine
 * Chlorpheniramine (Allergy)
 * chlorpheniramine 24 hour extended release
 * chlorpheniramine extended release
 * chlorpromazine
 * chlorpromazine extended release
 * ChlorTan
 * chlorthalidone
 * chlorzoxazone
 * clarithromycin
 * clarithromycin extended release
 * clemastine
 * clonidine
 * clonidine topical
 * Clopine
 * clorazepate
 * clorazepate extended release
 * clozapine
 * Clozapine Synthon
 * Clozaril
 * codeine
 * codeine phosphate
 * codeine sulfate
 * Codimal A
 * Cogentin
 * Compazine
 * Compazine Spansule
 * Compoz Nighttime Sleep Aid
 * Compro
 * Comtan
 * conivaptan
 * Contac 12 Hour Allergy
 * Cophene B
 * Cordron NR
 * Coreg
 * Coreg CR
 * Corgard
 * Corlopam
 * Cortastat
 * Cortastat 10
 * Cortastat LA
 * Cotolone
 * Covera-HS
 * Cozaar
 * cyclizine
 * cyclobenzaprine
 * cyclobenzaprine extended release
 * cyproheptadine
 * Cytadren
 * D-Vert
 * Dailyhist-1
 * Dalalone
 * Dalalone D.P.
 * Dalalone L.A.
 * Dalgan
 * Dalmane
 * Dantrium
 * Dantrium Intravenous
 * dantrolene
 * dasatinib
 * Dazidox
 * De-Sone LA
 * Decadron
 * Decadron 5-12 Pak
 * Decadron Phosphate Injectable
 * Decadron-LA
 * Decaject
 * Decaject L.A.
 * Dehydrated Alcohol
 * Deltasone
 * Demadex
 * Demadex I.V.
 * Demerol HCl
 * Denzapine
 * Depacon
 * Depakene
 * Depakote
 * Depakote ER
 * Depakote Sprinkles
 * Depo-Predate (obsolete)
 * DepoDur
 * Deponit
 * deserpidine
 * Dexacen-4
 * Dexacort Phosphate in Respihaler
 * Dexacort-LA
 * Dexacorten
 * dexamethasone
 * dexamethasone acetate
 * Dexamethasone Intensol
 * dexamethasone sodium phosphate
 * Dexasone
 * Dexasone LA
 * dexbrompheniramine
 * dexmedetomidine
 * Dexone
 * Dexone LA
 * Dexpak Jr. Taperpak
 * Dexpak Taperpak
 * dezocine
 * Di-Phen
 * Diaqua
 * Diaqua-2
 * diazoxide
 * Dibenzyline
 * Diflucan
 * dihydrocodeine
 * Dilacor XR
 * Dilantin
 * Dilantin Infatabs
 * Dilantin Kapseals
 * Dilantin-125
 * Dilatrate-SR
 * Dilaudid
 * Dilaudid-5
 * Dilaudid-HP
 * Diltia XT
 * diltiazem
 * diltiazem 24 hour extended release
 * diltiazem extended release
 * Diltiazem Hydrochloride CD
 * Diltiazem Hydrochloride SR
 * Diltiazem Hydrochloride XR
 * Diltiazem Hydrochloride XT
 * Dimetane
 * Dimetane Extentab
 * Dimetapp Allergy
 * Dimetapp Allergy Liquigel
 * Diovan
 * Diphedryl
 * Diphen
 * Diphen AF
 * Diphen Cough
 * Diphenadryl
 * Diphendryl
 * Diphenhist
 * diphenhydramine
 * diphenhydramine citrate
 * diphenhydramine tannate
 * Diphenmax
 * Diphenydramine Quick Melt
 * Diphenyl
 * Diphenylin
 * Diprivan
 * Diskets
 * Diucardin
 * Diurese
 * Diuril
 * Diuril Sodium
 * divalproex sodium
 * divalproex sodium extended release
 * Dolophine
 * Doloral
 * Doloral Sirop
 * Doral
 * Doxadura
 * doxazosin
 * doxazosin extended release
 * doxylamine
 * DPH
 * Dramamine II
 * Driminate II
 * Dromadol SR
 * Dromadol XL
 * dronabinol
 * droperidol
 * Duraclon
 * Duragesic
 * Duragesic-100
 * Duragesic-12
 * Duragesic-25
 * Duragesic-50
 * Duragesic-75
 * Duramorph PF
 * Dynacirc
 * Dynacirc CR
 * Dyrenium
 * Dytan
 * Dytuss
 * E-Mycin
 * E.E.S. Granules
 * E.E.S.-200
 * E.E.S.-400
 * E.E.S.-400 Filmtab
 * Ed Chlor-Tan
 * Ed ChlorPed
 * Edecrin
 * Edecrin Sodium
 * efavirenz
 * Efidac-24 Chlorpheniramine
 * Emend
 * Emend 3-Day
 * Emend for Injection
 * enalapril
 * enalaprilat
 * Endocodone
 * Enduron
 * entacapone
 * Epitol
 * eplerenone
 * eprosartan
 * Equanil
 * Equetro
 * Ery-Tab
 * Eryc
 * EryPed
 * EryPed 200
 * EryPed 400
 * Erythrocin Lactobionate
 * Erythrocin Stearate Filmtab
 * Erythrocot
 * erythromycin
 * erythromycin base
 * erythromycin estolate
 * erythromycin ethylsuccinate
 * erythromycin lactobionate
 * erythromycin stearate
 * Esidrix
 * Eskalith
 * Eskalith-CR
 * esmolol
 * estazolam
 * eszopiclone
 * ETH-Oxydose
 * ethacrynic acid
 * ethanol
 * ethchlorvynol
 * ethosuximide
 * ethotoin
 * Ethyl Alcohol
 * etravirine
 * Exna
 * Eze D.S.
 * Ezide
 * FazaClo
 * felbamate
 * Felbatol
 * felodipine
 * felodipine extended release
 * fenoldopam
 * fentanyl
 * fentanyl topical
 * Fentora
 * Fexmid
 * FK506
 * flavoxate
 * Flexeril
 * Flexoject
 * Flexon
 * Flo-Pred
 * fluconazole
 * fluphenazine
 * fluphenazine decanoate
 * fluphenazine enanthate
 * fluphenazine hydrochloride
 * flurazepam
 * Fortovase
 * fosamprenavir
 * fosaprepitant
 * fosinopril
 * fosphenytoin
 * furosemide
 * gabapentin
 * Gabarone
 * Gabitril
 * Genahist
 * GenRx Tramadol
 * Geodon
 * guanabenz
 * guanadrel
 * guanfacine
 * halazepam
 * Halcion
 * Harmonyl
 * HCTZ
 * Hexadrol
 * Hexadrol Phosphate
 * Histaject
 * Histex CT
 * Histex I/E
 * Histex PD
 * Histex Pd 12
 * Hydeltra-T.B.A.
 * Hydeltrasol
 * hydralazine
 * Hydramine
 * Hydramine Compound
 * Hydramine Cough Syrup
 * Hydro Par
 * hydrochlorothiazide
 * hydrocodone
 * hydrodiuril
 * hydroflumethiazide
 * Hydromorph Contin
 * hydromorphone
 * hydromorphone extended release
 * Hydrostat IR
 * hydroxyzine
 * hydroxyzine hydrochloride
 * hydroxyzine pamoate
 * Hygroton
 * Hylorel
 * Hyperstat
 * Hyrexin
 * Hytrin
 * Hyzine
 * Ilosone
 * Ilotycin Gluceptate
 * Imdur
 * Inapsine
 * indapamide
 * Inderal
 * Inderal LA
 * Infumorph
 * InnoPran XL
 * Inspra
 * Intelence
 * Invega
 * Invirase
 * Ionsys
 * Iopidine
 * irbesartan
 * ISDN
 * ISMO
 * Isochron
 * Isoptin
 * Isoptin I.V.
 * Isoptin SR
 * Isordil
 * Isordil Tembids
 * Isordil Titradose
 * isosorbide dinitrate
 * isosorbide dinitrate extended release
 * isosorbide mononitrate
 * isosorbide mononitrate extended release
 * isradipine
 * isradipine extended release
 * itraconazole
 * J-Tan
 * J-Tan PD
 * Kadian
 * Kemadrin
 * Keppra
 * Kerlone
 * Ketalar
 * ketamine
 * Ketek
 * Ketek Pak
 * ketoconazole
 * Key-Pred
 * Key-Pred SP
 * labetalol
 * Lamictal
 * Lamictal Blue
 * Lamictal CD
 * Lamictal Green
 * Lamictal Orange
 * lamotrigine
 * lapatinib
 * Larapam SR
 * Largon
 * Lasix
 * Levatol
 * levetiracetam
 * Levo-Dromoran
 * levocetirizine
 * levorphanol
 * Levrix
 * Lexiva
 * Librium
 * Lioresal
 * Lioresal Intrathecal
 * Liquid Pred
 * lisinopril
 * lithium
 * lithium carbonate
 * lithium carbonate extended release
 * lithium citrate
 * Lithobid
 * Lithonate
 * Lithotabs
 * Lo-Aqua
 * Lodrane 12 Hour
 * Lodrane 24
 * Lodrane XR
 * Loniten
 * Lopressor
 * Loqua
 * losartan
 * Lotensin
 * loxapine
 * Loxitane
 * Loxitane C
 * Loxitane IM
 * Lozol
 * Ludiomil
 * Luminal
 * Lunesta
 * Lyrica
 * M-Eslon
 * M-Oxy
 * M. O. S.
 * Maolate
 * maprotiline
 * Marezine
 * Marinol
 * Mavik
 * MB-TAB
 * Mebaral
 * Meclicot
 * meclizine
 * Medicort
 * Medidex
 * Medidex LA
 * Medivert
 * Mellaril
 * Mellaril-S
 * Meni-D
 * meperidine
 * mephenytoin
 * mephobarbital
 * meprobamate
 * Mesantoin
 * mesoridazine
 * Metahydrin
 * metaxalone
 * methadone
 * Methadose
 * methdilazine
 * methocarbamol
 * methsuximide
 * methyclothiazide
 * Meticorten
 * metoclopramide
 * metolazone
 * metoprolol
 * metoprolol extended release
 * metoprolol succinate
 * Metoprolol Succinate ER
 * metoprolol tartrate
 * mibefradil
 * Micardis
 * miconazole
 * Microzide
 * Midamor
 * midazolam
 * Mifeprex
 * mifepristone
 * Millipred
 * Milontin
 * Miltown
 * Minipress
 * Minitran
 * minoxidil
 * Mio-Rel
 * Mirapex
 * Mitran
 * Moban
 * modafinil
 * moexipril
 * molindone
 * Monistat I.V.
 * Monoket
 * Monopril
 * morphine
 * morphine 24 hour extended release
 * morphine extended release
 * Morphine IR
 * morphine liposomal
 * Morphine LP Epidural
 * morphine preservative-free
 * Morphine Rapi-Ject
 * Morphitec
 * MS
 * MS Contin
 * MS/S
 * MSIR
 * MY-E
 * Mycobutin
 * Mykrox
 * Myolin
 * Mysoline
 * nabilone
 * nadolol
 * nalbuphine
 * Naqua
 * Nasahist B
 * Naturetin-10
 * Naturetin-5
 * Navane
 * ND-Stat
 * nefazodone
 * nelfinavir
 * Nembutal
 * Nembutal Sodium
 * Nervine
 * Neupro
 * Neurontin
 * nevirapine
 * nicardipine
 * nicardipine extended release
 * Nifediac CC
 * Nifedical XL
 * nifedipine
 * nifedipine extended release
 * Nightime Sleepaid
 * nilotinib
 * nisoldipine
 * Nitrek
 * Nitro TD Patch-A
 * Nitro-Bid
 * Nitro-Bid IV
 * Nitro-Dur
 * Nitro-Par
 * Nitro-Time
 * Nitrocot
 * Nitrodisc
 * Nitrogard
 * nitroglycerin
 * Nitroglyn E-R
 * Nitrol
 * Nitrol Appli-Kit
 * Nitrolingual
 * Nitrong
 * Nitropress
 * nitroprusside
 * Nitroquick
 * Nitrostat
 * Nizoral
 * Nolahist
 * Norflex
 * Norflex Injectable
 * Normodyne
 * Norvasc
 * Norvir
 * Norvir Soft Gelatin
 * Noxafil
 * NTG
 * Nu-Med
 * Nubain
 * Numorphan HCl
 * Nuvigil
 * Nytol Caplet
 * Nytol Maximum Strength
 * olanzapine
 * olmesartan
 * olopatadine nasal
 * OMS
 * Opana
 * Opana ER
 * opium
 * Opium Deodorized
 * Optimine
 * Oramorph SR
 * Orap
 * Orapred
 * Orapred ODT
 * Orasone
 * Oretic
 * Orfro
 * Ormazine
 * orphenadrine
 * orphenadrine extended release
 * Orphenate
 * oxcarbazepine
 * oxycodone
 * oxycodone extended release
 * OxyContin
 * Oxyfast
 * oxyir
 * oxymorphone
 * oxymorphone extended release
 * P-Tann
 * P-Tex
 * Palgic
 * paliperidone
 * Palladone
 * Palladone SR
 * Paradione
 * Paraflex
 * Parafon Forte DSC
 * Paral
 * paraldehyde
 * paramethadione
 * Pardryl
 * Paregoric
 * Parlodel
 * Patanase
 * Paxarel
 * PBZ
 * PBZ-SR
 * PCE Dispertab
 * Pediapred
 * PediaTan
 * Pediatex
 * Pediatex 12
 * Pediox
 * Pediox-S
 * Peganone
 * penbutolol
 * Pentazine
 * pentazocine
 * pentobarbital
 * Percolone
 * pergolide
 * Periactin
 * perindopril
 * Permax
 * Permitil
 * perphenazine
 * phenacemide
 * Phenadoz
 * Phenazine 50
 * Phenergan
 * Phenergan Fortis
 * phenindamine
 * phenobarbital
 * Phenoject-50
 * phenoxybenzamine
 * phensuximide
 * phentolamine
 * Phenurone
 * phenylbutazone
 * phenyltoloxamine
 * Phenytek
 * phenytoin
 * phenytoin extended release
 * Phenytoin Sodium
 * Prompt
 * pimozide
 * pindolol
 * Placidyl
 * Plendil
 * polythiazide
 * posaconazole
 * Posicor
 * pramipexole
 * prazosin
 * Precedex
 * Pred-Ject-50
 * Predacort 50
 * Predaject-50
 * Predalone 50
 * Predate-50
 * Predcor
 * Predicort RP
 * Predicort-50
 * Prednicen-M
 * Prednicot
 * prednisolone
 * prednisolone acetate
 * prednisolone sodium phosphate
 * prednisolone tebutate
 * prednisone
 * pregabalin
 * Prelone
 * Pri-Cortin 50
 * Prialt
 * Priftin
 * Primethasone
 * primidone
 * Prinivil
 * Pro-Med
 * Procardia
 * Procardia XL
 * prochlorperazine
 * prochlorperazine extended release
 * Procot
 * procyclidine
 * Proglycem
 * Prograf
 * Prolixin
 * Prolixin Decanoate
 * Prolixin Enanthate
 * Promacot
 * promazine
 * promethazine
 * Promethegan
 * Prop-A-Tane
 * propiomazine
 * propofol
 * propranolol
 * propranolol extended release
 * Prorex
 * Prosom
 * Provigil
 * Q-Dryl
 * Q-Dryl A/F
 * QDALL AR
 * quazepam
 * Quenalin
 * quetiapine
 * quetiapine extended release
 * quinapril
 * ramipril
 * Rapamune
 * Rauwolfemms
 * Rauwolfia 1X
 * rauwolfia serpentina
 * Reglan
 * Relaxazone
 * remifentanil
 * Remular
 * Remular-S
 * Renese
 * Repreve
 * Requip
 * ReQuip Follow on Pack
 * Requip Starter Kit
 * ReQuip Starter Pack
 * Rescudose
 * reserpine
 * Restoril
 * Rezine
 * Ridramin
 * rifabutin
 * Rifadin
 * Rifadin IV
 * rifampin
 * rifapentine
 * Rimactane
 * Risperdal
 * Risperdal Consta
 * Risperdal M-Tab
 * risperidone
 * ritonavir
 * RMS
 * Robaxin
 * Robaxin-750
 * Robimycin
 * Rohist
 * ropinirole
 * rotigotine
 * Roxanol
 * Roxanol 100
 * Roxanol-T
 * Roxicodone
 * Roxicodone Intensol
 * RU-486
 * Ru-Vert-M
 * Saluron
 * saquinavir
 * saquinavir mesylate
 * Scot-Tussin Allergy Relief Formula
 * secobarbital
 * Seconal Sodium
 * Sectral
 * Serentil
 * Seroquel
 * Seroquel XR
 * Serzone
 * Siladryl
 * Siladryl DAS
 * Siladyl SA
 * Silphen Cough
 * Siltane
 * Simply Sleep
 * sirolimus
 * Skelaxin
 * Skelex
 * Sleep Tab II
 * Sleep Tabs
 * Sleep-ettes
 * Sleep-Eze-3
 * Sleepinal
 * sodium nitroprusside
 * sodium valproate
 * Solfoton
 * solotuss
 * Solurex
 * Solurex LA
 * Soma
 * Sominex
 * Sominex Maximum Strength Caplet
 * Somnicaps
 * Somnote
 * Sonata
 * Sorbitrate
 * Sorine
 * sotalol
 * Sotalol Hydrochloride AF
 * Sotalol Hydrochloride AF(obsolete)
 * Sparine
 * spironolactone
 * Sporanox
 * Sprycel
 * Stadol
 * Stadol NS
 * Statex
 * Stelazine
 * Sterapred
 * Sterapred DS
 * Strifon Fort
 * Sublimaze
 * Subutex
 * Sufenta
 * sufentanil
 * Sular
 * sulfinpyrazone
 * Sustiva
 * Tacaryl
 * tacrolimus
 * Talwin Lactate
 * Tanacof-XR
 * TanaHist-PD
 * Tao
 * Tasigna
 * Tasmar
 * Tavist
 * Tavist Allergy
 * Tavist-1
 * Taztia XT
 * Tegretol
 * Tegretol XR
 * telithromycin
 * telmisartan
 * Telzir
 * Temaril
 * temazepam
 * Tenex
 * Tenormin
 * terazosin
 * Terry White Chemists Tramadol
 * Teveten
 * thalidomide
 * Thalitone
 * Thalomid
 * Theraflu Thin Strips Multi Symptom
 * thiethylperazine
 * thioridazine
 * thiothixene
 * Thorazine
 * tiagabine
 * Tiazac
 * Ticon
 * Tigan
 * timolol
 * tizanidine
 * tolcapone
 * Topamax
 * Topamax Sprinkle
 * topiramate
 * Toprol-XL
 * Torecan
 * torsemide
 * Total Allergy
 * Tracleer
 * tramadol
 * tramadol extended release
 * Tramahexal
 * Tramahexal SR
 * Tramake
 * Tramake Insts
 * Tramal
 * Tramal SR
 * Tramedo
 * Trancopal
 * Trandate
 * trandolapril
 * Tranxene SD
 * Tranxene T-Tab
 * Triaminic Allergy
 * Triaminic Thin Strips Cough & Runny Nose
 * triamterene
 * triazolam
 * trichlormethiazide
 * Tridil
 * Tridione
 * trifluoperazine
 * triflupromazine
 * Trihexane
 * trihexyphenidyl
 * Trilafon
 * Trileptal
 * trimeprazine
 * trimethadione
 * trimethaphan camsylate
 * trimethobenzamide
 * tripelennamine
 * Tripohist
 * triprolidine
 * triprolidine extended release
 * troleandomycin
 * Trux-adryl
 * Tusstat
 * Twilite
 * Tykerb
 * Ultiva
 * Ultram
 * Ultram ER
 * Uni-Tann
 * Unisom
 * Unisom Sleepgels Maximum Strength
 * Univasc
 * Uprima
 * Urispas
 * Uroxatral
 * V-Gan-25
 * V-Gan-50
 * valproic acid
 * valsartan
 * Valu-Dryl
 * Vanadom
 * Vaprisol
 * Vasotec
 * VaZol
 * verapamil
 * verapamil 24 hour extended release
 * verapamil extended release
 * Verelan
 * Verelan PM
 * Versed
 * Vfend
 * Viracept
 * Viramune
 * Visken
 * Vistacon
 * Vistacot
 * Vistaject-50
 * Vistaril
 * Vistaril IM
 * Vistazine
 * Vistazine 50
 * voriconazole
 * Wal-finate
 * Wytensin
 * Xyzal
 * Xyzall
 * zaleplon
 * Zamadol
 * Zamadol 24hr
 * Zamadol Melt
 * Zamadol SR
 * Zanaflex
 * Zaponex
 * Zarontin
 * Zaroxolyn
 * Zebeta
 * Zestril
 * ziconotide
 * ziprasidone
 * zolpidem
 * zolpidem extended release
 * Zonegran
 * zonisamide
 * Zydol
 * Zydol SR
 * Zydol XL
 * Zymine
 * Zymine XR
 * Zyprexa
 * Zyprexa Zydis
 * Zyrtec
 * Zyrtec Hives

Minor Interactions

 * bexarotene
 * delavirdine
 * Haldol
 * Haldol Decanoate
 * haloperidol
 * haloperidol decanoate
 * Rescriptor
 * Targretin