Zolpidem instructions for administration

Overdosage topics
Dosage in adults Special populations Administration with CNS depressants Maximum daily dose

Dosage in adults
The dose of Zolpidem tartrate tablets should be individualized. The recommended dose for adults is 10 mg immediately before bedtime. Zolpidem tartrate tablets should not be administered with or immediately after a meal. Return to top

Special populations
Elderly or debilitated patients may be especially sensitive to the effects of Zolpidem tartrate tablets. Patients with hepatic insufficiency do not clear the drug as rapidly as normals. An initial 5 mg dose is recommended in these patients. Return to top

Administration with CNS depressants
Downward dosage adjustment may be necessary when Zolpidem tartrate tablets are administered with agents having known CNS-depressant effects because of the potentially additive effects. Return to top

Maximum daily dose
The total Zolpidem tartrate tablet dose should not exceed 10 mg per day. As with the management of all overdosage, the possibility of multiple drug ingestion should be considered. The physician may wish to consider contacting a poison control center for up-to-date information on the management of hypnotic drug product overdosage. Return to top