Phosphoenolpyruvate mutase

In enzymology, a phosphoenolpyruvate mutase is an enzyme that catalyzes the chemical reaction


 * phosphoenolpyruvate $$\rightleftharpoons$$ 3-phosphonopyruvate

Hence, this enzyme has one substrate, phosphoenolpyruvate, and one product, 3-phosphonopyruvate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is phosphoenolpyruvate 2,3-phosphonomutase. Other names in common use include phosphoenolpyruvate-phosphonopyruvate phosphomutase, PEP phosphomutase, phosphoenolpyruvate phosphomutase, PEPPM, and PEP phosphomutase. This enzyme participates in aminophosphonate metabolism.

Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes, , , , , and.