Pyruvate, phosphate dikinase

In enzymology, a pyruvate, phosphate dikinase is an enzyme that catalyzes the chemical reaction


 * ATP + pyruvate + phosphate $$\rightleftharpoons$$ AMP + phosphoenolpyruvate + diphosphate

The 3 substrates of this enzyme are ATP, pyruvate, and phosphate, whereas its 3 products are AMP, phosphoenolpyruvate, and diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with paired acceptors. The systematic name of this enzyme class is ATP:pyruvate, phosphate phosphotransferase. Other names in common use include pyruvate, orthophosphate dikinase, pyruvate-phosphate dikinase (phosphorylating), pyruvate, phosphate dikinase, pyruvate-inorganic phosphate dikinase, pyruvate-phosphate dikinase, pyruvate-phosphate ligase, pyruvic-phosphate dikinase, pyruvic-phosphate ligase, pyruvate, Pi dikinase, and PPDK. This enzyme participates in pyruvate metabolism and carbon fixation.

Structural studies
As of late 2007, 10 structures have been solved for this class of enzymes, with PDB accession codes, , , , , , , , , and.