(+)-abscisic acid 8'-hydroxylase

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In enzymology, a (+)-abscisic acid 8'-hydroxylase (EC is an enzyme that catalyzes the chemical reaction

(+)-abscisate + NADPH + H+ + O2 8'-hydroxyabscisate + NADP+ + H2O

The 4 substrates of this enzyme are (+)-abscisate, NADPH, H+, and O2, whereas its 3 products are 8'-hydroxyabscisate, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating). Other names in common use include (+)-ABA 8'-hydroxylase, and ABA 8'-hydroxylase. This enzyme participates in carotenoid biosynthesis - general.


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  • Cutler AJ, Squires TM, Loewen MK and Balsevich JJ (1997). "Induction of (+)-abscisic acid 8' hydroxylase by (+)-abscisic acid in cultured maize cells". J. Exp. Bot. 48: 1787&ndash, 1795.
  • Krochko JE, Abrams GD, Loewen MK, Abrams SR, Cutler AJ (1998). "(+)-Abscisic acid 8'-hydroxylase is a cytochrome P450 monooxygenase". Plant. Physiol. 118: 849&ndash, 60. PMID 9808729.

External links

Gene Ontology (GO) codes