(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase

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In enzymology, a (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase (EC is an enzyme that catalyzes the chemical reaction

(1-hydroxycyclohexan-1-yl)acetyl-CoA acetyl-CoA + cyclohexanone

Hence, this enzyme has one substrate, (1-hydroxycyclohexan-1-yl)acetyl-CoA, and two products, acetyl-CoA and cyclohexanone.

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming). This enzyme is also called (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase.


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  • Ougham HJ, Trudgill PW (1982). "Metabolism of cyclohexaneacetic acid and cyclohexanebutyric acid by Arthrobacter sp. strain CA1". J. Bacteriol. 150: 1172&ndash, 82. PMID 7076617.

External links

The CAS registry number for this enzyme class is 71343-09-4.

Gene Ontology (GO) codes