1,2-dihydrovomilenine reductase

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In enzymology, a 1,2-dihydrovomilenine reductase (EC is an enzyme that catalyzes the chemical reaction

17-O-acetylnorajmaline + NADP+ 1,2-dihydrovomilenine + NADPH + H+

Thus, the two substrates of this enzyme are 17-O-acetylnorajmaline and NADP+, whereas its 3 products are 1,2-dihydrovomilenine, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 17-O-acetylnorajmaline:NADP+ oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis.


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  • Gao S, von Schumann G, Stockigt J (2002). "A newly-detected reductase from Rauvolfia closes a gap in the biosynthesis of the antiarrhythmic alkaloid ajmaline". Planta. Med. 68: 906&ndash, 11. PMID 12391554.

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Gene Ontology (GO) codes