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In enzymology, a 1,6-alpha-D-mannosidase (EC is an enzyme that catalyzes the chemical reaction of separating the 1,6-linked alpha-D-mannose residues in alpha-D-Manp-(1->6)-D-Manp.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is 1,6-alpha-mannosyl alpha-D-mannohydrolase.


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  • Athanasopoulos VI, Niranjan K, Rastall RA (2005). "The production, purification and characterisation of two novel alpha-D-mannosidases from Aspergillus phoenicis". Carbohydr. Res. 340: 609&ndash, 17. PMID 15721331.

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