1-alkylglycerophosphocholine O-acyltransferase

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In enzymology, a 1-alkylglycerophosphocholine O-acyltransferase (EC 2.3.1.63) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine CoA + 2-acyl-1-alkyl-sn-glycero-3-phosphocholine

Thus, the two substrates of this enzyme are acyl-CoA and 1-alkyl-sn-glycero-3-phosphocholine, whereas its two products are CoA and 2-acyl-1-alkyl-sn-glycero-3-phosphocholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase. This enzyme participates in ether lipid metabolism.

References

  • IUBMB entry for 2.3.1.63
  • BRENDA references for 2.3.1.63 (Recommended.)
  • PubMed references for 2.3.1.63
  • PubMed Central references for 2.3.1.63
  • Google Scholar references for 2.3.1.63
  • Waku K, Nakazawa Y (Tokyo). "Acyltransferase activity to 1-O-alkyl-glycero-3-phosphorylcholine in sarcoplasmic reticulum". J. Biochem.: 459&ndash, 66. PMID 5488773. Check date values in: |date= (help)
  • Waku K, Nakazawa Y (Tokyo). "Acyltransferae activity to 1-acyl-, 1-O-alkenyl-, and 1-O-alkyl-glycero-3-phosphorylcholine in Ehrlich ascites tumor cells". J. Biochem.: 495&ndash, 7. PMID 4644313. Check date values in: |date= (help)

External links

The CAS registry number for this enzyme class is 58693-63-3.

Gene Ontology (GO) codes


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