2,3-Dimercapto-1-propanesulfonic acid
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| 2,3-Dimercapto-1-propanesulfonic acid | |
|---|---|
| Image:2,3-Dimercapto-1-propanesulfonic acid.png | |
| Identifiers | |
| CAS number | |
| PubChem | |
| MeSH | |
| SMILES | OS(=O)(=O)CC(S)CS |
| Properties | |
| Molecular formula | C3H8O3S3 |
| Molar mass | 188.289 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
2,3-Dimercapto-1-propanesulfonic acid (abbreviated DMPS) or its sodium salt (known as Unithiol) are chelating agents that form complexes with various heavy metals. It is related to dimercaprol, which is another chelating agent.
The synthesis of DMPS was first reported in 1956 by scientists in the Soviet Union.[citation needed] The effects if DMPS on heavy metal poisoning, including with polonium-210 were investigated in the following years. DMPS was found to have some protective effect, prolonging the survival time.[1]
A study was done of workers involved in the production of a calomel skin-bleaching lotion and in direct contact with mercurous chloride, who already showed elevated urine mercury levels. The sodium salt of (DMPS) was found to be effective in lowering the body burden of mercury and in decreasing the urinary mercury concentration to normal levels.[1]
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
