Aceclidine
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| Image:Aceclidine.png | |
| Aceclidine
| |
| Systematic (IUPAC) name | |
| 1-azabicyclo[2.2.2]oct-8-yl acetate | |
| Identifiers | |
| CAS number | (or 6109-70-2 [HCl]) |
| ATC code | S01 |
| PubChem | |
| Chemical data | |
| Formula | C9H15NO2 |
| Mol. mass | 169.221 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
℞ Prescription only |
| Routes | Ocular |
Aceclidine (INN) (trade names Glaucostat, Glaunorm, Glaudin) is a parasympathomimetic miotic agent used in the treatment of narrow angle glaucoma. It decreases intraocular pressure.
Mechanism of action
Aceclidine acts primarily on the muscarinic receptor.
Side effects
Side effects of aceclidine include increased salivation, bradycardia (in excessive doses).
References
- ACECLIDINE CHLORHYDRATE [Article in French] Biam. Last update: 2 September 1999. Accessed 13 September 2005 (UTC)
- ACECLIDINE (АЦЕКЛИДИН) [Article in Russian] ViDAL 2005. Accessed 13 September 2005.
Ophthalmologicals: antiglaucoma preparations and miotics (S01E) | |
|---|---|
| Sympathomimetics | Apraclonidine • Brimonidine • Clonidine • Dipivefrine • Epinephrine |
| Parasympathomimetics | Aceclidine • Acetylcholine • Carbachol • Demecarium • Echothiophate • Stigmine (Fluostigmine, Neostigmine, Physostigmine) • Paraoxon • Pilocarpine |
| Carbonic anhydrase inhibitors | Acetazolamide • Brinzolamide • Diclofenamide • Dorzolamide • Methazolamide |
| Beta blocking agents | Befunolol • Betaxolol • Carteolol • Levobunolol • Metipranolol • Timolol |
| Prostaglandin analogues | Bimatoprost • Latanoprost • Travoprost • Unoprostone |
| Other agents | Dapiprazole • Guanethidine |
