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In enzymology, an alkylhalidase (EC is an enzyme that catalyzes the chemical reaction

bromochloromethane + H2O formaldehyde + bromide + chloride

Thus, the two substrates of this enzyme are bromochloromethane and H2O, whereas its 3 products are formaldehyde, bromide, and chloride.

This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is alkyl-halide halidohydrolase. Other names in common use include halogenase, haloalkane halidohydrolase, and haloalkane dehalogenase.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Heppel LA and Porterfield VT (1948). "Enzymatic dehalogenation of certain brominated and chlorinated compounds". J. Biol. Chem. 176: 763&ndash, 769.

External links

The CAS registry number for this enzyme class is 9025-22-3.

Gene Ontology (GO) codes