Iduronidase
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| iduronidase, alpha-L-
| |
| Identifiers | |
| Symbol | IDUA |
| Entrez | 3425 |
| HUGO | 5391 |
| OMIM | 252800 |
| RefSeq | NM_000203 |
| UniProt | P35475 |
| Other data | |
| EC number | 3.2.1.76 |
| Locus | Chr. 4 p16.3 |
Iduronidase is an enzyme involved in the degeneration of dermatan sulfate.
Pathology
Its deficiency is associated with Hurler syndrome.
External links
Hydrolase: sugar hydrolases (EC 3.2) | |
|---|---|
| 3.2.1: Glycoside hydrolases | Amylase (Alpha-Amylase) - Chitinase - Lysozyme - Neuraminidase - Galactosidases (Alpha, Beta) - alpha-Mannosidase - Glucuronidase - Hyaluronidase - Pullulanase - Glucocerebrosidase - Galactosylceramidase - Alpha-N-acetylglucosaminidase - Fucosidase - Hexosaminidase - Iduronidase - Disaccharidase (Sucrase/Sucrase-isomaltase/Invertase, Maltase, Trehalase, Lactase) - Glucosidases (Cellulase, Alpha-glucosidase, Beta-glucosidase, Debranching enzyme) |
| 3.2.2: Hydrolysing N-Glycosyl compounds | DNA glycosylases: Oxoguanine glycosylase |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
