Amodiaquine
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Image:Amodiaquine.svg | |
| Amodiaquine
| |
| Systematic (IUPAC) name | |
| 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol | |
| Identifiers | |
| CAS number | |
| ATC code | P01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C20H22ClN3O |
| Mol. mass | 355.861 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | 5.2 ± 1.7 (range 0.4 to 5.5) minutes |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Amodiaquine (trade names Camoquin, Flavoquine) is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.
Amodiaquine has been shown to be more effective than chloroquine in treating CRPF (chloroquine-resistant Plasmodium falciparum) malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine, like chloroquine, is generally well tolerated. Although licensed, this drug is not marketed in the United States but is widely available in Africa. Its use, therefore, is probably more practicable in long-term visitors and persons who will reside in Africa.[1]
Notes
Antiprotozoals: Antimalarial drugs (P01B) | |
|---|---|
| Aminoquinolines | 4-Aminoquinoline (Amodiaquine, Chloroquine, Hydroxychloroquine) • 8-Aminoquinoline (Pamaquine, Primaquine) |
| Methanolquinolines | Mefloquine • Quinine |
| Biguanides | Proguanil • Cycloguanil embolate |
| Diaminopyridines | Pyrimethamine |
| Artemisinin derivatives | Artemisinin • Artemether • Artesunate • Artenimol • Arteether/Artemotil |
| Others | Halofantrine • Lumefantrine |
 | This antimicrobial-related article is a stub. You can help Wikipedia by expanding it. |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
