Naproxen
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Synonyms / Brand Names: Aleve, Anaprox, Bonyl, DL Naproxen, DL-Naproxen, Diocodal, Dysmenalgit, Ec-naprosyn, Equiproxen, Floginax, Laraflex, Laser, Mnpa, Naixan, Naprelan, Napren, Naprium, Naprius, Naprosine, Naprosyn, Naprosyne, Naproxen Sodium, Naprux, Naxen, Naxyn, Niaxan, Nycopren, Panoxen, Pranoxen, Prexan, Proxen, Proxine, Reuxen, Veradol, Xenar x
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
Dosing and Administration
Geriatric Patients
Studies indicate that although total plasma concentration of Naproxen is unchanged, the unbound plasma fraction of Naproxen is increased in the elderly. Caution is advised when high doses are required and some adjustment of dosage may be required in elderly patients. As with other drugs used in the elderly, it is prudent to use the lowest effective dose.
Patients with Moderate to Severe Renal Impairment
Naproxen-containing products are not recommended for use in patients with moderate to severe and severe renal impairment (creatinine clearance < 30 mL/min).
Rheumatoid Arthritis, Osteoarthritis and Ankylosing Spondylitis
- 275 mg (Naproxen 250 mg with 25 mg sodium) twice daily
- or 550 mg (Naproxen 500 mg with 50 mg sodium) twice daily
For more information on dosing please refer to Instructions for administration
FDA Package Insert Resources
Indications, Contraindications, Side Effects, Drug Interactions, etc.
Calculate Creatine Clearance
On line calculator of your patients Cr Cl by a variety of formulas.
Convert pounds to Kilograms
On line calculator of your patients weight in pounds to Kg for dosing estimates.
Publication Resources
Recent articles, WikiDoc State of the Art Review, Textbook Information
Trial Resources
Ongoing Trials, Trial Results
Guidelines & Evidence Based Medicine Resources
US National Guidelines, Cochrane Collaboration, etc.
Media Resources
Slides, Video, Images, MP3, Podcasts, etc.
Patient Resources
Discussion Groups, Handouts, Blogs, News, etc.
International Resources
en Español
FDA Package Insert Resources
Indications
Contraindications
Side Effects
Drug Interactions
Precautions
Overdose
Instructions for Administration
How Supplied
Pharmacokinetics and Molecular Data
FDA label
FDA on Naproxen
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Publication Resources
Most Recent Articles on Naproxen
Review Articles on Naproxen
Articles on Naproxen in N Eng J Med, Lancet, BMJ
WikiDoc State of the Art Review
Textbook Information on Naproxen
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Trial Resources
Ongoing Trials with Naproxen at Clinical Trials.gov
Trial Results with Naproxen
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Guidelines & Evidence Based Medicine Resources
US National Guidelines Clearinghouse on Naproxen
Cochrane Collaboration on Naproxen
Cost Effectiveness of Naproxen
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Media Resources
Powerpoint Slides on Naproxen
Images of Naproxen
Podcasts & MP3s on Naproxen
Videos on Naproxen
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Patient Resources
Patient Resources on Naproxen
Discussion Groups on Naproxen
Patient Handouts on Naproxen
Blogs on Naproxen
Naproxen in the News
Naproxen in the Marketplace
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International Resources
Naproxen en Español
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The content of this page is taken from the FDA package insert for this drug and should not be edited.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
