Aniracetam
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Aniracetam | |
|---|---|
| IUPAC name | 1-[(4-methoxybenzoyl)]- 2-pyrrolidinone |
| Identifiers | |
| CAS number | |
| PubChem | |
| SMILES | COC1=CC=C(C=C1)C(=O)N2CCCC2=O |
| Properties | |
| Molecular formula | C12H13NO3 |
| Molar mass | 219.237 |
| Pharmacology | |
| Bioavailability | ~100% |
| Routes of administration | Oral and parenteral |
| Elimination half-life | 4 - 5 hr |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
Aniracetam (Draganon®, Sarpul®, Ampamet®) is a nootropic drug of the racetam family purported to be considerably more potent than piracetam. It is lipid soluble and has possible cognition enhancing effects. It has been tested in animals extensively, Alzheimer's patients and temporarily-impaired healthy subjects, but has not been tested in healthy, unimpaired humans. It has shown potential as an anxiolytic in three clinical animal models.
Contents |
Pharmacology
After a confirmed test of the anxiolytic efficacy in a mouse model, receptor antagonists haloperidol, mecamylamine, and ketanserin were applied. Haloperidol completely reversed the anxiolytic effects, and mecamylamine and ketanserin nearly completely reversed the effects. This shows that aniracetam's anxiolytic mechanism is facilitated by D2/D3 dopamine, nicotinic acetylcholine, and 5-HT2A receptors[1].
See also
External links
References
Racetams |
|---|
| Aniracetam • Brivaracetam • Coluracetam • Etiracetam/Levetiracetam • Fasoracetam • Nebracetam • Nefiracetam • Oxiracetam • Phenylpiracetam • Piracetam • Pramiracetam • Rolipram • Rolziracetam • Seletracetam |
Psychoanaleptics: psychostimulants, agents used for ADHD and nootropics (N06B) | |
|---|---|
| Centrally acting sympathomimetics | Amphetamine - Amphetaminil - Atomoxetine - Dextroamphetamine - Dextromethamphetamine - Fencamfamin - Fenozolone - Fenetylline - Methylphenidate - Mesocarb - Pemoline - Pipradrol - Prolintane |
| Xanthine derivatives | Caffeine - Propentofylline |
| Racetams | Aniracetam - Oxiracetam - Phenylpiracetam - Piracetam - Pramiracetam |
| Ampakines | CX-516 - CX-546 - CX-614 - CX-691 - CX-717 - IDRA-21 - LY-503,430 - PEPA |
| Eugeroics | Adrafinil - Armodafinil - Modafinil |
| Other psychostimulants and nootropics | Acetylcarnitine - Citicoline - Cyprodenate - Idebenone - Deanol - Dimebon - Fipexide - Linopirdine - Meclofenoxate - Nizofenone - Pirisudanol - Pyritinol - Sulbutiamine - Vinpocetine |
 | This pharmacology-related article is a stub. You can help WikiDoc by expanding it. |
