Armodafinil
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| Image:(R)-modafinil.svg | |
| Armodafinil
| |
| Systematic (IUPAC) name | |
| (-)-2-[(R)-(diphenylmethyl)sulfinyl]acetamide | |
| Identifiers | |
| CAS number | |
| ATC code | N06 |
| PubChem | |
| Chemical data | |
| Formula | C15H15NO2S |
| Mol. mass | 273.351 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | Hepatic, including CYP3A4 and other pathways |
| Half life | 12-15 hrs |
| Excretion | Urine (as metabolites) |
| Therapeutic considerations | |
| Pregnancy cat. |
C |
| Legal status |
Schedule IV (USA) |
| Routes | Oral |
Armodafinil (Nuvigil®) is an eugeroic drug produced by the pharmaceutical company Cephalon Inc., which was approved by the FDA on June 15, 2007.
Cephalon plans to conduct clinical trials evaluating the use of Nuvigil as a treatment for serious medical conditions such as bipolar depression, cognition associated with schizophrenia, and excessive sleepiness and fatigue in conditions such as Parkinson's disease and cancer.
Nuvigil is protected by a U.S. patent expiring in 2023 that claims the Form 1 polymorph of armodafinil.
See also
External links
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
