Beauvericin
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| Beauvericin | |
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| Image:Beauvericin.svg | |
| IUPAC name | (3S,6R,9S,12R,15S,18R)-6,12,18-triisopropyl- 4,10,16-trimethyl-3,9,15-tris(phenylmethyl)- 1,7,13-trioxa-4,10,16-triazacyclooctadecane- 2,5,8,11,14,17-hexone |
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| Properties | |
| Molecular formula | C45H57N3O9 |
| Molar mass | 783.940 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
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Beauvericin is a toxic depsipeptide with antibiotic and insecticidal effects belonging to the enniatin family. It was isolated from the fungus Beauveria bassiana, but is also produced by several other fungi, including several Fusarium species;[1] it may therefore occur in grain (such as corn, wheat and barley) contaminated with these fungi.[1][1][1] Beauvericin is active against Gram-positive bacteria and mycobacteria, and is also capable of inducing programmed cell death in mammals.[1]
Chemically, beauvericin is a cyclic hexadepsipeptide with alternating methyl-phenylalanyl and hydroxy-iso-valeryl residues. Its ion-complexing capability allows beauvericin to transport alkaline earth metal and alkali metal ions across cell membranes.
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
