Benzylthiouracil

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Benzylthiouracil
Systematic (IUPAC) name
1-(1-cyclohexa-2,4-dienylmethyl)-7-thia-
3,5-diazabicyclo[4.1.0]hepta-3,5-dien-2-one
Identifiers
CAS number 6336-50-1
ATC code H03BA03
PubChem 685814
Chemical data
Formula C11H10N2OS 
Mol. mass 218.276 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral

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Benzylthiouracil

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Benzylthiouracil (BTU) is an antithyroid preparation. It is a thioamide, closely related to propylthiouracil.

Adverse effects

Benzylthiouracil has been associated with severe adverse effects, notably vasculitis and subsequent ANCA-positive glomerulonephritis, as well as isolated reports of lung damage.[1][1][1][1]

References

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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