Blind loop syndrome
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Overview
Blind loop syndrome is a medical condition that occurs when the intestine is obstructed, slowing or stopping the progress of digested food, and thus facilitating the growth of bacteria to the point that problems in nutrient absorption occur.
Physiology
The obstruction of a section of intestine causes ineffective bile salt mediated digestion of fats, causing fatty stools and poor absorption of fat and fat-soluble vitamins. Vitamin B12 deficiency may occur because the increased bacterial population can consume the vitamin.
Causes
Blind loop syndrome is a complication of surgical operations of the abdomen, as well as inflammatory bowel disease or scleroderma.
Symptoms
- Loss of appetite
- Nausea
- Diarrhea
- Fullness after a meal
- Fatty stools
- Unintentional weight loss
Signs and tests
A physical examination may reveal a mass or distention of the abdomen.
Tests which may be useful for diagnosis include:
- Abdominal x-ray
- Abdominal CT scan
- Contrast enema study
Treatment
The initial treatment generally involves antibiotics for the bacterial overgrowth, along with vitamin B12 supplementation. If antibiotics are not successful, surgical correction of the obstruction to allow better flow of food through the intestine may be considered.
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

