Brenner tumor

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Brenner tumor
Classification and external resources
ICD-9 220
ICD-O: 9000

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Brenner tumor

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Overview

Brenner tumors are uncommon tumors that are part of the surface epithelial-stromal tumor group of ovarian neoplasms. The majority of these tumors are benign and incidental findings on pelvic examination or at laparotomy.

On gross pathological examination, they are solid, sharply circumscribed and pale yellow-tan in colour. 90% are unilateral (arising in one ovary, the other is unaffected). The tumors can vary in size from less than 1 cm to 30 cm. Borderline and malignant Brenner tumors are possible but each are rare. Histologically, there are nests of transitional-type epithelial cells with longitudinal nuclear grooves (coffee bean nuclei) lying in abundant fibrous stroma.

Transitional cell carcinoma is an even more rare entity, in which neoplastic transitional epithelial cells similar to transitional cell carcinoma of the bladder are seen in the ovary, without the characteristic stromal/epithelial pattern of a Brenner tumor.

Brenner tumors very rarely can occur in other locations, including testis.

External links

de:Brenner-Tumor
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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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