CURB-65

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CURB-65 is a clinical prediction rule that has been validated for predicting mortality in community-acquired pneumonia^[1] and infection of any site^[1]. The CURB-65 is based on the earlier CURB score^[1] and is recommended by the British Thoracic Society for the assessment of severity of pneumonia.^[1]

The score is an acronym for each of the risk factors measured. Each risk factor scores one point, for a maximum score of 5:

• confusion (defined as an AMT of 8 or less)
• urea greater than 7 mmol/l (Blood Urea Nitrogen > 20)
• respiratory rate of 30 breaths per minute or greater
• blood pressure less than 90 systolic or diastolic blood pressure 60 or less
• age 65 or older

Predicting death from pneumonia

The risk of death increases as the score increases:

• 0—0.7%
• 1—3.2%
• 2—13.0%
• 3—17.0%
• 4—41.5%
• 5—57.0%

The CURB-65 has been compared to the pneumonia severity index in predicting mortality from pneumonia.^[1]

Predicting death from any infection

A cohort study of patients with any type of infection (half of the patients had pneumonia), the risk of death increases as the score increases^[1]:

• 0 to 1 <5% mortality
• 2 to 3 < 10% mortality
• 4 to 5 15-30% mortality

References

External links

• British Thoracic Society
• ICU Medicus Pneumonia Severity Score - online calculator for the CURB-65

v • d • e WikiDoc Research Resources for CURB-65
Articles on CURB-65	Most recent articles on CURB-65 • Most cited articles on CURB-65 • Review articles on CURB-65 • Articles on CURB-65 in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on CURB-65	Powerpoint slides on CURB-65 • Images of CURB-65 • Photos of CURB-65 • Podcasts & MP3s on CURB-65 • Videos on CURB-65
Evidence Based Medicine Regarding CURB-65	Cochrane Collaboration on CURB-65 • Bandolier on CURB-65 • TRIP on CURB-65
Cost Effectiveness of CURB-65	Cost Effectiveness of CURB-65
Clinical Trials Involving CURB-65	Ongoing Trials on CURB-65 at Clinical Trials.gov • Trial results on CURB-65 • Clinical Trials on CURB-65 at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding CURB-65	US National Guidelines Clearinghouse on CURB-65 • NICE Guidance on CURB-65 • NHS PRODIGY Guidance • FDA on CURB-65 • CDC on CURB-65
Textbook Information on CURB-65	Books and Textbook Information on CURB-65
Pharmacology Resources on CURB-65	Dosing of CURB-65 • Drug interactions with CURB-65 • Side effects of CURB-65 • Allergic reactions to CURB-65 • Overdose information on CURB-65 • Carcinogenicity information on CURB-65 • CURB-65 in pregnancy • Pharmacokinetics of CURB-65 •
Genetics, Pharmacogenomics, and Proteinomics of CURB-65	Genetics of CURB-65 • Pharmacogenomics of CURB-65 • Proteomics of CURB-65
Newstories on CURB-65	CURB-65 in the news • Be alerted to news on CURB-65 • News trends on CURB-65
Commentary on CURB-65	Blogs on CURB-65
Patient Resources on CURB-65	Patient resources on CURB-65 • Discussion groups on CURB-65 • Patient Handouts on CURB-65 • Directions to Hospitals Treating CURB-65 • Risk calculators and risk factors for CURB-65
Healthcare Provider Resources on CURB-65	Symptoms of CURB-65 • Causes & Risk Factors for CURB-65 • Diagnostic studies for CURB-65 • Treatment of CURB-65
Continuing Medical Education (CME) Programs on CURB-65	CME Programs on CURB-65
International Resources on CURB-65	CURB-65 en Espanol • CURB-65 en Francais
Business Resources on CURB-65	CURB-65 in the Marketplace • Patents on CURB-65
Informatics Resources on CURB-65	List of terms related to CURB-65

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .