CXCL5
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| chemokine (C-X-C motif) ligand 5
| |
| Identifiers | |
| Symbol | CXCL5 |
| Alt. Symbols | SCYB5, ENA-78 |
| Entrez | 6374 |
| HUGO | 10642 |
| OMIM | 600324 |
| RefSeq | NM_002994 |
| UniProt | P42830 |
| Other data | |
| Locus | Chr. 4 q21 |
Chemokine (C-X-C motif) ligand 5 (CXCL5) is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha.[1] Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II interferon IFN-γ.[1] This chemokine stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2.[1] The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes.[1][1] CXCL5 has been implicated in connective tissue remodelling.[1]
References
Cytokines: chemokines | |
|---|---|
| CCL | CCL1 - CCL2 - CCL3 - CCL4 - CCL5 - CCL6 - CCL7 - CCL8 - CCL9 - CCL10 - CCL11 - CCL12 - CCL13 - CCL14 - CCL15 - CCL16 - CCL17 - CCL18 - CCL19 - CCL20 - CCL21 - CCL22 - CCL23 - CCL24 - CCL25 - CCL26 - CCL27 - CCL28 |
| CXCL | CXCL1 - CXCL2 - CXCL3 - CXCL4 - CXCL5 - CXCL6 - CXCL7 - CXCL8 - CXCL9 - CXCL10 - CXCL11 - CXCL12 - CXCL13 - CXCL14 - CXCL15 - CXCL16 - CXCL17 |
| CX3CL | CX3CL1 |
| XCL | XCL1 - XCL2 |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
