Calcium citrate
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
| Calcium citrate | |
|---|---|
| |
| IUPAC name | 2-hydroxy-1,2,3-propane- tricarboxylic acid calcium salt (2:3) |
| Other names | E333 |
| Identifiers | |
| CAS number | |
| SMILES | C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O. C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O. [Ca+2].[Ca+2].[Ca+2] |
| Properties | |
| Molecular formula | Ca3(C6H5O7)2 |
| Molar mass | 498.46 g/mol (anhydrous) |
| Appearance | White powder |
| Density | 1.63 g/cm3, solid |
| Melting point |
120 °C (loses water) |
| Boiling point |
Decomposes |
| Solubility in water | 0.095 g/100 ml (25 °C) |
| Hazards | |
| MSDS | External MSDS |
| Main hazards | Irritant |
| Related Compounds | |
| Other cations | Sodium citrate |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
|
WikiDoc Resources for Calcium citrate | |
|
Articles | |
|---|---|
|
Most recent articles on Calcium citrate Most cited articles on Calcium citrate | |
|
Media | |
|
Powerpoint slides on Calcium citrate | |
|
Evidence Based Medicine | |
|
Clinical Trials | |
|
Ongoing Trials on Calcium citrate at Clinical Trials.gov Trial results on Calcium citrate Clinical Trials on Calcium citrate at Google
| |
|
Guidelines / Policies / Govt | |
|
US National Guidelines Clearinghouse on Calcium citrate NICE Guidance on Calcium citrate
| |
|
Books | |
|
News | |
|
Commentary | |
|
Definitions | |
|
Patient Resources / Community | |
|
Patient resources on Calcium citrate Discussion groups on Calcium citrate Patient Handouts on Calcium citrate Directions to Hospitals Treating Calcium citrate Risk calculators and risk factors for Calcium citrate
| |
|
Healthcare Provider Resources | |
|
Causes & Risk Factors for Calcium citrate | |
|
Continuing Medical Education (CME) | |
|
International | |
|
| |
|
Businness | |
|
Experimental / Informatics | |
Calcium citrate is the calcium salt of citric acid. It is commonly used as a food additive (E333), usually as a preservative, but sometimes for flavor. In this sense, it is similar to sodium citrate. Calcium citrate is also used as a water softener because the citrate ions can chelate unwanted metal ions. Calcium citrate is also found in some dietary calcium supplements.
Chemical properties
Like citric acid, calcium citrate has a sour taste. Like other salts, however, it also has a salty taste. For this reason, citrates such as sodium and calcium citrate are commonly known as sour salt.
Production
Calcium citrate is an intermediate in the isolation of citric acid from the fermentation process by which citric acid is produced industrially.[1] The citric acid in the broth solution is neutralized by calcium hydroxide, precipitating insoluble calcium citrate. This is then filtered off from the rest of the broth and washed to give clean calcium citrate.
The calcium citrate thus produced may be sold as-is, or it may be converted to citric acid using dilute sulfuric acid.
Biological role
Calcium citrate supplements may increase aluminum toxicity. Patients with renal disease are at an increased risk of toxicity.
Bioavailability is 2.5 times higher than calcium carbonate. For this reason, patients who have undergone the Roux-en-Y variety of weight-loss surgery (also known as gastric bypass) are usually instructed to take calcium citrate as a dietary supplement.
References
de:Calciumcitratit:Citrato di calcio
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
