Canine coronavirus
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Canine coronavirus | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Image:Canine coronavirus.jpg Canine coronavirus antigen in canine lung tissue
| ||||||||||
| Virus classification | ||||||||||
|
Canine coronavirus is a virus of the family Coronaviridae that causes a highly contagious intestinal disease worldwide in dogs. It was discovered in 1971 in Germany during an outbreak in sentry dogs.[1]
Contents |
Canine enteric coronavirus
Pathology
The virus invades and replicates in the villi of the small intestine. Intestinal disease may be related to virus-induced apoptosis (programmed cell death) of cells of the epithelial mucosa of the small intestine.[1] Canine coronavirus was originally thought to cause serious gastrointestinal disease, but now most cases are considered to be very mild or without symptoms.[1] A more serious complication of canine coronavirus occurs when the dog is also infected with canine parvovirus. Coronavirus infection of the intestinal villi makes the cells more susceptible to parvovirus infection. This causes a much more severe disease than either virus can separately.[1] However, fatal intestinal disease associated with canine coronavirus without the presence of canine parvovirus is still occasionally reported.[1][1] This may be related to the high mutation rate of RNA positive stranded viruses, of which canine coronavirus is one.[1]
Symptoms, diagnosis, treatment, and control
The incubation period is only one to three days.[1] The disease is highly contagious and is spread through the feces of infected dogs, who usually shed the virus for six to nine days, but sometimes for six months following infection.[1] Symptoms include diarrhea, vomiting, and anorexia. Diagnosis is through detection of virus particles in the feces. Treatment usually only requires medication for diarrhea, but more severely affected dogs may require intravenous fluids for dehydration. Fatalities are rare. The virus is destroyed by most available disinfectants. There is a vaccine available, and it is usually given to puppies, who are more susceptible to canine coronavirus, and to dogs that have a high risk of exposure, such as show dogs.[1]
Canine respiratory coronavirus
Recently, a second type of canine coronavirus (Group II) has been shown to cause respiratory disease in dogs.[1] Known as canine respiratory coronavirus (CRCoV) and found to be similar to strain OC43 of bovine and human coronaviruses, it was first isolated in the United Kingdom in 2003 from lung samples of dogs[1] and has since been found on the European mainland[1] and in Japan.[1] A serological study in 2006 has also shown antibodies to CRCoV to be present in dogs in Canada and the United States.[1] However, a retrospective study in Saskatchewan found that CRCoV may have been present there as far back as 1996.[1]
References
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
