Carbamoyl phosphate
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(Redirected from Carbamyl phosphate)
| Carbamoyl phosphate | |
|---|---|
| Image:CarbPhos.png | |
| Identifiers | |
| CAS number | |
| PubChem | |
| MeSH | |
| Properties | |
| Molecular formula | CH4NO5P |
| Molar mass | 141.020 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
Carbamoyl phosphate is an anion of biochemical significance. It is involved In ridding the body of excess nitrogen in the urea cycle, and also in the synthesis of pyrimidines.
It is produced from bicarbonate, ammonia, and phosphate, the latter derived from ATP. The synthesis is catalysed by the enzyme carbamoyl phosphate synthase, as follows:
- HCO3- + ATP --> ADP + HO-C(O)-OPO3-2 (carbonyl phosphate)
- HO-C(O)-OPO3-2 + NH3 + OH- → HPO42- + -O-C(O)NH2 + H2O
- -O-C(O)NH2 + ATP → ADP + H2NC(O)OPO32-
See also
Sources
- Nelson, David L. and Michael M. Fox. Lehninger Principles of Biochemistry fourth edition. W. H. Freeman and company New York.
