Cat scratch fever
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| Cat scratch fever Classification and external resources | |
| ICD-10 | A28.1 |
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| ICD-9 | 078.3 |
| DiseasesDB | 2173 |
| eMedicine | emerg/84 |
| MeSH | D002372 |
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Cat scratch fever is a usually benign infectious disease caused by the intracellular parasite Bartonella. It is most commonly found in children 1-2 weeks following a cat scratch. It was first described in 1889 by Henri Parinaud. The cat was recognized as the vector of the disease in 1931 by Dr. Robert Debré.
The causative organism was first thought to be Afipia felis, but this was disproved by immunological studies demonstrating that cat scratch fever patients developed antibodies to two other organisms, Bartonella henselae and Bartonella clarridgeiae, which are rod-shaped Gram negative bacteria.
Kittens are more likely to carry the bacteria in their blood, and are therefore more likely to transmit the disease than are adult cats.
Ticks are also a major transmitter of this disease. It is often transmitted at the same time a human may get Lyme Disease. It is often missed when people are tested and diagnosed for Lyme Disease as the symptoms can be similar, such as fatigue, and headaches.
A simple blood test can test for the presence of antibodies for Bartonella. It can be quite common for someone to have Lyme Disease, Babesia and Bartonella from a single tick bite.
Other names
The condition has also been termed Cat-Scratch Adenitis, Cat-Scratch-Oculoglandular Syndrome, Debre's Syndrome, Debre-Mollaret Syndrome, Foshay-Mollaret Cat-Scratch Fever, Foshay-Mollaret syndrome, Foshay-Mollaret Cat-Scratch Fever Syndrome, Lymphadenitis-Regional Non-bacterial, Lymphoreticulosis-Benign Inoculation, maladie des griffes du chat, Parinaud oculoglandular disease, and Petzetakis' disease.
Signs and symptoms
Cat scratch fever presents with tender regional lymphadenopathy, sterile suppurative papules at the site of inoculation, slight fever, headache, chills, backache, abdominal pain, malaise, alteration of mental status, and convulsions. It may take 7 to 14 days, or as long as two months, before symptoms appear. Most cases are benign and self-limiting, but lymphadenopathy may persist for several months after other symptoms disappear. The prognosis is generally favorable. In temperate climates, most cases occur in fall and winter. The disease usually resolves spontaneously, with or without treatment, in one month. In immunocompromised patients more severe complications sometimes occur.
Treatment
Azithromycin, Ciprofloxacin, doxycycline, and multiple other antibiotics have been used successfully.
External links
- Cat Scratch Disease on National Organization for Rare Disorders site
ar:مرض خدش القطة de:Katzenkratzkrankheitfr:Maladie des griffes du chat it:Malattia da graffio di gatto ja:猫ひっかき病 sv:Cat scratch fever
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| Articles on Cat scratch fever | Most recent articles on Cat scratch fever • Most cited articles on Cat scratch fever • Review articles on Cat scratch fever • Articles on Cat scratch fever in N Eng J Med, Lancet, BMJ |
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| Evidence Based Medicine Regarding Cat scratch fever | Cochrane Collaboration on Cat scratch fever • Bandolier on Cat scratch fever • TRIP on Cat scratch fever |
| Cost Effectiveness of Cat scratch fever | Cost Effectiveness of Cat scratch fever |
| Clinical Trials Involving Cat scratch fever | Ongoing Trials on Cat scratch fever at Clinical Trials.gov • Trial results on Cat scratch fever • Clinical Trials on Cat scratch fever at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Cat scratch fever | US National Guidelines Clearinghouse on Cat scratch fever • NICE Guidance on Cat scratch fever • NHS PRODIGY Guidance • FDA on Cat scratch fever • CDC on Cat scratch fever |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
