Cathine
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| Cathine
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| Systematic (IUPAC) name | |
| 2-amino-1-phenyl-propan-1-ol | |
| Identifiers | |
| CAS number | |
| ATC code | A08 |
| PubChem | |
| Chemical data | |
| Formula | C9H13NO |
| Mol. mass | 151.206 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | Chewing Catha edulis leaves. |
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Ongoing Trials on Cathine at Clinical Trials.gov Clinical Trials on Cathine at Google
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US National Guidelines Clearinghouse on Cathine
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Directions to Hospitals Treating Cathine Risk calculators and risk factors for Cathine
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Cathine (β-hydroxyamphetamine) is a monoamine alkaloid found in the shrub Catha edulis (khat).
Pharmacology
Closely related to ephedrine, cathinone and other amphetamines, it may contribute to the stimulant effect of Catha edulis, although another constituent, cathinone appears to show stronger activity. Cathine is one of the optical isomers of phenylpropanolamine, an appetite suppressant and decongestant which is possibly associated with an increased risk of hemorrhagic stroke.
Regulation
The World Anti-Doping Agency's list of prohibited substances (used for the Olympic Games among other athletic events) bars cathine in concentrations of over 5 micrograms per milliliter in urine. Cathine is a Schedule III drug under the Convention on Psychotropic Substances.[1] In the United States, it is classified as a Schedule IV controlled substance.
In Hong Kong, Cathine is regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance. It can only be used legally by health professionals and for university research purporses. The substance can be given by pharmacists under a prescription. Anyone who supplies the substance without prescription can be fined $10000(HKD). The penalty for trafficking or manufacturing the substance is a $5,000,000 (HKD) fine and life imprisonment. Possession of the substance for consumption without license from the Department of Health is illegal with a $1,000,000 (HKD) fine and/or 7 years of jail time.
References
See also
- Catha edulis
- Cathinone
- Methcathinone
- Phenylpropanolamine
- Phenethylamines
Antiobesity preparations (A08) | |
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| Centrally acting | Phentermine - Fenfluramine - Amfepramone - Dexfenfluramine - Mazindol - Cathine - Clobenzorex - Sibutramine - Rimonabant - Taranabant |
| Peripherally acting | Orlistat |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
