Cefazolin
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Image:Cefazolin.png | |
| Cefazolin
| |
| Systematic (IUPAC) name | |
| 3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]- 8-oxo-7-([2-(tetrazol-1-yl)acetyl]amino)- 5-thia-1-azabicyclo[4.2.0] oct-2-ene-2-carboxylate | |
| Identifiers | |
| CAS number | |
| ATC code | J01 |
| PubChem | |
| Chemical data | |
| Formula | C14H13N8O4S3 |
| Mol. mass | 454.51 g/mol |
| Pharmacokinetic data | |
| Bioavailability | NA |
| Metabolism | ? |
| Half life | 1.8 hours (given IV) 2 hours (given IM) |
| Excretion | Renal, unchanged |
| Therapeutic considerations | |
| Pregnancy cat. | |
| Legal status |
℞ Prescription only |
| Routes | Intravenous, intramuscular |
|
WikiDoc Resources for Cefazolin | |
|
Articles | |
|---|---|
|
Most recent articles on Cefazolin | |
|
Media | |
|
Evidence Based Medicine | |
|
Clinical Trials | |
|
Ongoing Trials on Cefazolin at Clinical Trials.gov Clinical Trials on Cefazolin at Google
| |
|
Guidelines / Policies / Govt | |
|
US National Guidelines Clearinghouse on Cefazolin
| |
|
Books | |
|
News | |
|
Commentary | |
|
Definitions | |
|
Patient Resources / Community | |
|
Patient resources on Cefazolin Discussion groups on Cefazolin Directions to Hospitals Treating Cefazolin Risk calculators and risk factors for Cefazolin
| |
|
Healthcare Provider Resources | |
|
Causes & Risk Factors for Cefazolin | |
|
Continuing Medical Education (CME) | |
|
International | |
|
| |
|
Businness | |
|
Experimental / Informatics | |
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Cefazolin (INN), also known as cefazoline or cephazolin, is a first generation cephalosporin antibiotic.
The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion (intravenous fluid into a vein).
Indications
Cefazolin is mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is clinically effective against infections caused by staphylococci and streptococci species of Gram positive bacteria. These organisms are common on normal human skin. Resistance to cefazolin is seen in several species of bacteria.
Side effects
Side effects from cefazolin are not common. Possible side effects include:
- diarrhea
- stomach pain
- upset stomach
- vomiting
Cefazolin is marketed under the following brand names: Ancef®, Cefacidal®, Cefamezin®, Cefrina®, Elzogram®, Faxilen®, Gramaxin®, Kefazol®, Kefol®, Kefzol®, Kefzolan®, Kezolin®, Novaporin®, and Zolicef®
External links
- MedlinePlus Drug Information: Cefazolin Sodium Injection.
- Eli Lilly Cefazolin Sodium Material Safety Data Sheet.
Antibacterials for systemic use: beta-lactam antibiotics - cephalosporins and related (J01D) | |
|---|---|
| First generation | Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole |
| Second generation | Cefaclor, Cefamandole, Cefmetazole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime |
| Third generation | Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Ceftibuten, Ceftizoxime, Ceftriaxone, Latamoxef |
| Fourth generation | Cefepime, Cefpirome, Cefquinome |
| Fifth generation | Ceftobiprole |
| Other beta-lactam antibacterials | Monobactams (Aztreonam), Carbapenems (Parenteral - Meropenem, Ertapenem, Imipenem, Doripenem, Oral - Faropenem) |
fr:Céfazolineth:เซฟาโซลิน de:Cefazolin
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
