Cethromycin
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| Cethromycin
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| Systematic (IUPAC) name | |
| (1S, 2R, 5R, 7R, 8R, 9S, 11R, 13R, 14R) -8- [(2S, 3R, 4S, 6R) -4- Dimethylamino -3- hydroxy -6- methyloxan -2-yl] oxy-2-ethyl-1, 5, 7, 9, 11, 13-hexamethyl -9- [(E) -3- quinolin -3- ylprop -2- enoxy] -3, 17-dioxa -15-azabicyclo [12.3.0]heptadecane -4, 6, 12, 16-tetrone | |
| Identifiers | |
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| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C42H59N3O10 |
| Mol. mass | 765.931 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
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| Legal status | |
| Routes | Oral |
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WikiDoc Resources for Cethromycin | |
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Most recent articles on Cethromycin Most cited articles on Cethromycin | |
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Powerpoint slides on Cethromycin | |
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Evidence Based Medicine | |
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Clinical Trials | |
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Ongoing Trials on Cethromycin at Clinical Trials.gov Clinical Trials on Cethromycin at Google
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Guidelines / Policies / Govt | |
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US National Guidelines Clearinghouse on Cethromycin
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Patient Resources / Community | |
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Patient resources on Cethromycin Discussion groups on Cethromycin Patient Handouts on Cethromycin Directions to Hospitals Treating Cethromycin Risk calculators and risk factors for Cethromycin
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Healthcare Provider Resources | |
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Causes & Risk Factors for Cethromycin | |
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Continuing Medical Education (CME) | |
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Experimental / Informatics | |
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Overview
Cethromycin (initially known as ABT-773) is a macrolide antibiotic undergoing research for the treatment of community acquired pneumonia (CAP) and for the prevention of post-exposure inhalational anthrax, and was given an "orphan drug" status for this indication.[1] Originally discovered and developed by Abbott, it was acquired by Advanced Life Sciences Inc. for further development.
On April 10, 2008, Advanced Life Sciences announced that, based on a productive meeting with the U.S. Food and Drug Administration (FDA), it plans to submit a New Drug Application (NDA) in the third quarter of 2008 for cethromycin to treat mild-to-moderate community acquired pneumonia.[1]
References
Antibacterials for systemic use: macrolides, lincosamides and streptogramins (J01F) | |
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| Macrolides | Erythromycin - Spiramycin - Midecamycin - Oleandomycin - Roxithromycin - Josamycin - Troleandomycin - Clarithromycin - Azithromycin - Miocamycin - Rokitamycin - Dirithromycin - Flurithromycin - Telithromycin - Cethromycin |
| Lincosamides | Clindamycin - Lincomycin |
| Streptogramins | Pristinamycin - Quinupristin/dalfopristin |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
