Clonus
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Ongoing Trials on Clonus at Clinical Trials.gov Clinical Trials on Clonus at Google
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US National Guidelines Clearinghouse on Clonus
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Directions to Hospitals Treating Clonus Risk calculators and risk factors for Clonus
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Clonus (from the Greek for "violent, confused motion") is a series of involuntary muscular contractions due to sudden stretching of the muscle. Clonus is a sign of certain neurological conditions, and is particularly associated with so-called upper motor neuron lesions such as amyotrophic lateral sclerosis (ALS), stroke, multiple sclerosis or spinal cord damage. Unlike the small, spontaneous twitching known as fasciculations (usually caused by lower motor neuron pathology), clonus causes large motions that are usually initiated by a reflex.
Clonus is most common in the ankles, where it is tested by rapidly flexing forward (dorsiflexing) the relaxed ankle. It can also be tested in the knees by rapidly pushing the patella towards the toes. Only sustained clonus (5 beats or more) is considered abnormal. Clonus could be caused by the use of magnesium sulfate
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External links
de:Klonuslt:Traukuliai ja:クローヌス
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
