Co-proxamol
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| Co-proxamol
| |
| Combination of | |
| Dextropropoxyphene | Opioid analgesic |
| Paracetamol | Non-opioid analgesic |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | Oral |
Co-proxamol (BAN, also coproxamol) is a combination of the analgesics dextropropoxyphene (an opioid) and paracetamol.
The UK Medicines and Healthcare products Regulatory Agency (MHRA) decided in 2005 to withdraw co-proxamol from the market following advice from the Committee on Safety of Medicines (CSM) that co-proxamol is little more effective than paracetamol alone as an analgesic, but that it was associated with higher fatality rates if a drug overdose were intentionally or inadvertently taken. The decision provoked some outcry from long-term users of the drug.
References
- Suicide painkiller withdrawn. The Times (January 31, 2005).
- Painkiller scrapped over suicides. BBC News (January 31, 2005).
- Co-proxamol to be withdrawn from the market. Medicines and Healthcare products Regulatory Agency (31 January 2005).
- Withdrawal of co-proxamol. Medicines and Healthcare products Regulatory Agency (17 January 2007).
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
