Complement component 1S
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| The C1 protein, showing subunits C1r, C1s, and the C1q tails. | |
| complement component 1, s subcomponent
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| Identifiers | |
| Symbol | C1S |
| Entrez | 716 |
| HUGO | 1247 |
| OMIM | 120580 |
| RefSeq | NM_001734 |
| UniProt | P09871 |
| Other data | |
| EC number | 3.4.21.42 |
| Locus | Chr. 12 p13 |
Complement component 1S is a protein involved in the complement system.
C1s cleaves C4, which eventually leads to the production of the C4b-C2a form of C3-convertase.
External links
Proteins: complement system (C, L, A) | |
|---|---|
| Activators | CLA: C3-convertase - MAC (C6, C7, C8, C9) - L: Mannan-binding lectin - A: Factor P/Properdin |
| Enzymes | C: C1Q/C1R/C1S - C4 - C2 - CLA: C3 - C5 (C5a) - L: MASP1 - MASP2 - A: Factor B - Factor D |
| Inhibitors | CLA: C1-inhibitor - Decay accelerating factor - Factor I - CL: C4BP - A: Factor H |
| Complement receptors | CR1 - CR2 - CR3 - CR4 - CD11b/CD11c/CD18 - Anaphylatoxin (C3a, C5a) |
