Connecting tubule
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| Connecting tubule | |
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| Scheme of renal tubule and its vascular supply. | |
| Latin | tubulus renalis arcuatus |
| Gray's | subject #253 1223 |
| Precursor | Metanephric blastema |
| Dorlands/Elsevier | t_22/12830099 |
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In the kidney, the collecting tubule (CNT, or junctional tubule, or arcuate renal tubule) is a tubular segment of the renal collecting duct system that connects the distal convoluted tubule to the cortical collecting duct.
Classification
Many sources include the connecting tubule as part of the collecting duct system. However, the embryological origin is more similar to the nephron than it is to the rest of the collecting duct (which derives from the ureteric bud), and other sources therefore classify the connecting tubule with the nephron.
Naming
Some connecting tubules, usually associated with juxtamedullary nephrons, arch upwards before reaching the cortical collecting ducts. It is this "arcuate" feature which gives the tubule its alternate name.
Function
It participates in the regulation of water and electrolytes, including sodium, and chloride.
The CNT is sensitive to both isoprotenerol (more so than the cortical collecting ducts) and antidiuretic hormone (less so than the cortical collecting ducts), the latter largely determining its function in water reabsorption.
References
- Eaton, Douglas C., Pooler, John P. (2004). Vander's Renal Physiology, 6th edition, Lange Medical Books/McGraw-Hill. ISBN 0-07-135728-9.
- Imai M (1979). "The connecting tubule: a functional subdivision of the rabbit distal nephron segments". Kidney Int 15 (4): 346-56. PMID 513494.
External links
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
