Stroma of cornea
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| Stroma of cornea | |
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| Vertical section of human cornea from near the margin. (Waldeyer.) Magnified. 1. Epithelium. 2. Anterior elastic lamina. 3. substantia propria. 4. Posterior elastic lamina. 5. Endothelium of the anterior chamber. a. Oblique fibers in the anterior layer of the substantia propria. b. Lamellæ the fibers of which are cut across, producing a dotted appearance. c. Corneal corpuscles appearing fusiform in section. d. Lamellæ the fibers of which are cut longitudinally. e. Transition to the sclera, with more distinct fibrillation, and surmounted by a thicker epithelium. f. Small blood vessels cut across near the margin of the cornea. | |
| Latin | s. propria corneae |
| Gray's | subject #225 1007 |
| Dorlands/Elsevier | s_27/12766936 |
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The substantia propria (or stroma of cornea) is fibrous, tough, unyielding, and perfectly transparent.
It is composed of about 200 flattened lamellæ, superimposed one on another.[1] These fibrils run at different angles between limbi. Fibres of the layers frequently interweave, the anterior lamellæ interweaving more than posterior lamellæ. The fibres of each lamella are parallel with one another, but at right angles to those of adjacent lamellæ. The lamellæ are produced by keratocytes, which occupy about 10% of the substantia propria.
These lamellæ are made up of bundles of modified connective tissue, the fibres of which are directly continuous with those of the sclera. More collagen fibres run in a temporal-nasal direction than run in the superior-inferior direction. This is often ignored by corneal transplant surgeons, leading to poor corneal mechanical strength in corneal transplant patients.
Keratoconus is a condition caused by disorganised lamellæ, leading to a bulbous cornea.
References
External links
Sensory system - Visual system - Eye | |
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| Fibrous tunic (outer) | Conjunctiva • Sclera • Schlemm's canal • Trabecular meshwork • Limbus Cornea (Epithelium, Bowman's, Stroma, Descemet's, Endothelium) |
| Uvea (middle) | Choroid (Ciliary processes, Choriocapillaris, Bruch's membrane) • Iris (Stroma) • Pupil • Ciliary body |
| Retina (inner) | Macula • Fovea • Optic disc |
| Anterior segment | Anterior chamber • Aqueous humour • Posterior chamber • Lens |
| Posterior segment | Vitreous humour • Zonule of Zinn |
| Intraocular muscles | parasympathetic (Ciliary muscle, Iris sphincter muscle) • sympathetic (Iris dilator muscle) |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
