Cyclobenzaprine side effects

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884

List of side effects

Acute musculoskeletal conditions

Tricyclic antidepressants

Enhancement to CNS depressants



Acute musculoskeletal conditions

Cyclobenzaprine is closely related to the tricyclic antidepressants, e.g., amitriptyline and imipramine. In short term studies for indications other than muscle spasm associated with acute musculoskeletal conditions, and usually at doses somewhat greater than those recommended for skeletal muscle spasm, some of the more serious central nervous system reactions noted with the tricyclic antidepressants have occurred. Return to top

Tricyclic antidepressants

Tricyclic antidepressants have been reported to produce arrhythmias, sinus tachycardia, prolongation of the conduction time leading to myocardial infarction and stroke. Return to top

Enhancement to CNS depressants

Cyclobenzaprine HCl may enhance the effects of alcohol, barbiturates, and other CNS depressants. Return to top



The content of this page is taken from the FDA package insert for this drug and should not be edited.

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