Diego antigen system
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The Diego blood group
History
The Diego system was discovered in 1955 in one Mrs. Diego when her child was found to suffer from HDN. The child was type Dia. A second type Dib was discovered in 1967 but the other types only began to be discovered in 1995. [1] , [1]
Definition
Blood is classified in the Diego system by the form of the band 3 protein, coded for by the gene SLC41A (Solute Carrier family 4, Anion exchanger, member 1). Each allele of the gene SLC41A is classified as a separate blood group. The band 3 protein functions in the transport of Cl- and carbonate.
The system
There are 21 known Diego blood types, the most common is Di(a-b+); found in over 99.9% of Caucasians and Blacks, and in about 90% of Asians. Most of the remaining 10% of Asians are (a+b+). The cultural distribution of the blood group lends it some importance to the science of anthropology. [1]
References
Transfusion medicine | |
|---|---|
| General concepts | Apheresis (Plasmapheresis, Plateletpheresis, Leukapheresis) - Blood transfusion - Coombs test - Cross-matching - Exchange transfusion - International Society of Blood Transfusion - Intraoperative blood salvage - ISBT 128 - Transfusion reactions |
| Human blood group systems - Blood type | ABO - Chido-Rodgers - Colton - Cromer - Diego - Dombrock - Duffy - Gerbich - GIL - Hh - Ii - Indian - JMH - Kell (Xk) - Kidd - Knops - LW - Lewis - Lutheran - MNS - OK - P - Raph - Rh - Scianna - T-Tn - Xg - Yt - Other |
| Blood products | Blood donation - Blood substitutes - Cryoprecipitate - Platelets - Plasma - Red blood cells - Whole blood |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
