Dyslipidemia

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Dyslipidemia Classification and external resources
ICD-10	E78.
ICD-9	272
MeSH	C18.452.339

Dyslipidemia is a disruption in the amount of lipids in the blood.

In western societies, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood, often due to diet and lifestyle. The prolonged elevation of insulin levels can lead to dyslipidemia.

Contents 1 Classification 2 Types 2.1 Increases 2.2 Decreases

Classification

There are two major ways in which dyslipidemias are classified:

• Phenotype, or the presentation in the body (including the specific type of lipid that is increased)
• Etiology, or the reason for the condition (genetic, or secondary to another condition.) This classification can be problematic, because most conditions involve the intersection of genetics and lifestyle issues. However, there are a few well defined genetic conditions that are usually easy to identify.

Types

Increases

These conditions are discussed in greater detail at hyperlipidemia.

• Hyperlipidemia: lipids
  • Hypercholesterolemia: cholesterol
  • Hyperglyceridemia: glycerides
    • Hypertriglyceridemia: triglycerides
• Hyperlipoproteinemia: lipoproteins (usually LDL unless otherwise specified)
  • Hyperchylomicronemia: chylomicrons
• Combined hyperlipidemia: both LDL and triglycerides

Familial hypercholesterolemia is a specific form of hypercholesterolemia due to a defect on chromosome 19 (19p13.1-13.3).

Decreases

• Hypolipoproteinemia: lipoproteins
• Hypocholesterolemia: cholesterol
• Abetalipoproteinemia: beta lipoproteins
• Tangier disease: high density lipoprotein

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