Embolization

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Embolization is a non-surgical, minimally-invasive procedure performed by an interventional radiologist and interventional neuroradiologists. It involves the selective occlusion of blood vessels, by purposely introducing emboli.

Therapeutic Applications

Embolisation is used to treat a wide variety of conditions affecting different organs of the human body.

Haemorrage

The treatment is used to occlude:

• AVMs
• Cerebral aneurysm
• Gastrointestinal bleeding
• Epistaxis

Growths

• In the liver, typically HCC lesions. Either by infarction or TACE (Transcatheter arterial chemoembolization).
• Kidney lesions
• Uterine fibroids

The Procedure

The procedure is a minimally-invasive alternative to surgery. The purpose of embolization is to prevent blood flow to an area of the body, which effectively can shrink a tumour or block an aneurysm.

The procedure is carried out as an endovascular procedure, by a Consultant Radiologist in an Interventional Suite. It is common for most patients to have the treatment carried out with little or no sedation, although this depends largely on the organ to be embolized. Patients who undergo Cerebral Embolization or Portal Vein Embolization are usually given a general anesthetic.

Access to the organ in question is acquired by means of a guidewire and catheter(s). Depending on the organ this can be very difficult and time consuming. The position of the correct artery or vein supplying the pathology in question is located by Digital subtraction angiography or DSA. These images are then used as a map for the radiologist to gain access to the correct vessel by selecting an appropriate catheter and or wire, depending on the 'shape' of the surrounding anatomy.

Once in place, the treatment can begin. The artificial embolus used is usually one of three things:

• Coils: Guglielmi Detachable Coil or Hydrocoil
• Particles
• Foam

Once the artificial emboli have been successfully introduced, another set of DSA images are taken to confirm a successful deployment.

Advantages

• Minimally invasive
• No scarring
• Minimal risk of infection
• No or rare use of general anaesthetic
• Faster recovery time

Disadvantages

• User dependant success rate
• Risk of emboli reaching healthy tissue
• Not suitable for everyone

External links

• Site for women which compares surgery and endovascular treatment of fibroids
• Learn more about AVM's
• Information on cerebral embolisations
• eMedicine: Embolization

See also

• Endovascular surgery
• Interventional radiology
• Surgery
• Uterine fibroids
• Hepatocellular carcinoma
• Arteriovenous malformation
• Cerebral aneurysm
• Gastrointestinal bleedingko:색전술

Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .