Empyema

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Empyema
Classification and external resources
ICD-10 J86.
ICD-9 510
DiseasesDB 4200
MedlinePlus 000123
eMedicine med/659 
MeSH D016724

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An empyema, also known as a pyothorax, is a collection of pus within the pleural cavity. It must be differentiated from an abscess, which is a collection of pus in a newly formed cavity. Most empyemas arise from an infection within the lung (pneumonia), often associated with parapneumonic effusions.

There are 3 stages: exudative, fibrinopurulent and organizing. In the exudative stage, the pus accumulates. This is followed by the fibrinopurulent stage in which there is loculation of the pleural fluid (the creation of grapelike pus pockets). In the final organizing stage, scarring of the pleural space may lead to lung entrapment.

Pleural space empyema

Symptoms

Symptoms of empyema may vary in severity. Typical symptoms include: fever, chest pain or discomfort, cough, sweating and shortness of breath.

Clubbing of the fingernails may be present. There is a dull percussion note and reduced breath sounds on the affected side of the chest. Other diagnostic tools include chest x-ray, CT scan, and Ultrasonography.

Diagnosis

Diagnosis is confirmed by thoracentesis; frank pus may be aspirated from the pleural space. The pleural fluid typically has a low pH (<7.20), low glucose (<60 mg/dL), and contains infectious organisms.

CT chest showing large right sided hydropneumothorax from pleural empyema. Arrows A: air, B: fluid
CT chest showing large right sided hydropneumothorax from pleural empyema. Arrows A: air, B: fluid

Treatment

Definitive treatment for empyema entails drainage of the infected pleural fluid. A chest tube may be inserted, often using ultrasound guidance. Intravenous antibiotics are given. If this is insufficient, surgical debridement of the pleural space may be required.

External links

de:Empyem

et:Empüeem ja:膿胸

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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