Cardiac fibrosis

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

WikiDoc Resources for Cardiac fibrosis
Articles
Most recent articles on Cardiac fibrosis Most cited articles on Cardiac fibrosis Review articles on Cardiac fibrosis Articles on Cardiac fibrosis in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Cardiac fibrosis Images of Cardiac fibrosis Photos of Cardiac fibrosis Podcasts & MP3s on Cardiac fibrosis Videos on Cardiac fibrosis
Evidence Based Medicine
Cochrane Collaboration on Cardiac fibrosis Bandolier on Cardiac fibrosis TRIP on Cardiac fibrosis
Clinical Trials
Ongoing Trials on Cardiac fibrosis at Clinical Trials.gov Trial results on Cardiac fibrosis Clinical Trials on Cardiac fibrosis at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Cardiac fibrosis NICE Guidance on Cardiac fibrosis NHS PRODIGY Guidance FDA on Cardiac fibrosis CDC on Cardiac fibrosis
Books
Books on Cardiac fibrosis
News
Cardiac fibrosis in the news Be alerted to news on Cardiac fibrosis News trends on Cardiac fibrosis
Commentary
Blogs on Cardiac fibrosis
Definitions
Definitions of Cardiac fibrosis
Patient Resources / Community
Patient resources on Cardiac fibrosis Discussion groups on Cardiac fibrosis Patient Handouts on Cardiac fibrosis Directions to Hospitals Treating Cardiac fibrosis Risk calculators and risk factors for Cardiac fibrosis
Healthcare Provider Resources
Symptoms of Cardiac fibrosis Causes & Risk Factors for Cardiac fibrosis Diagnostic studies for Cardiac fibrosis Treatment of Cardiac fibrosis
Continuing Medical Education (CME)
CME Programs on Cardiac fibrosis
International
Cardiac fibrosis en Espanol Cardiac fibrosis en Francais
Businness
Cardiac fibrosis in the Marketplace Patents on Cardiac fibrosis
Experimental / Informatics
List of terms related to Cardiac fibrosis

Cardiology Network
Discuss Cardiac fibrosis further in the WikiDoc Cardiology Network
Adult Congenital
Biomarkers
Cardiac Rehabilitation
Congestive Heart Failure
CT Angiography
Echocardiography
Electrophysiology
Cardiology General
Genetics
Health Economics
Hypertension
Interventional Cardiology
MRI
Nuclear Cardiology
Peripheral Arterial Disease
Prevention
Public Policy
Pulmonary Embolism
Stable Angina
Valvular Heart Disease
Vascular Medicine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

Overview

Cardiac fibrosis refers to an abnormal thickening of the heart valves due to inappropriate proliferation of cardiac fibroblasts.

Pathophysiology

These cells secrete collagen, and normally function to provide structural support for the heart. When over activated this process causes thickening and fibrosis, primarily on the tricuspid valve, but also occurring on the pulmonary valve, eventually leading to right-sided heart failure.

Certain diseases such as gastrointestinal carcinoid tumors, which release large amounts of serotonin into the blood, produce a characteristic pattern of mostly right sided cardiac fibrosis which can be identified at autopsy. This pathology has also been seen in certain african tribes who eat foods containing excess amounts of serotonin.

Some appetite suppressant drugs such as fenfluramine and chlorphentermine induce a similar pattern of cardiac fibrosis, by over-stimulating 5HT_2B receptors on the cardiac fibroblast cells. These drugs consequently tended to cause increased risk of heart valve damage and subsequent heart failure, which eventually led to them being withdrawn from the market.

A compound found in red wine, resveratrol has been found to slow down the development of cardiac fibrosis.

v • d • e WikiDoc Research Resources for Cardiac fibrosis
Articles on Cardiac fibrosis	Most recent articles on Cardiac fibrosis • Most cited articles on Cardiac fibrosis • Review articles on Cardiac fibrosis • Articles on Cardiac fibrosis in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Cardiac fibrosis	Powerpoint slides on Cardiac fibrosis • Images of Cardiac fibrosis • Photos of Cardiac fibrosis • Podcasts & MP3s on Cardiac fibrosis • Videos on Cardiac fibrosis
Evidence Based Medicine Regarding Cardiac fibrosis	Cochrane Collaboration on Cardiac fibrosis • Bandolier on Cardiac fibrosis • TRIP on Cardiac fibrosis
Cost Effectiveness of Cardiac fibrosis	Cost Effectiveness of Cardiac fibrosis
Clinical Trials Involving Cardiac fibrosis	Ongoing Trials on Cardiac fibrosis at Clinical Trials.gov • Trial results on Cardiac fibrosis • Clinical Trials on Cardiac fibrosis at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Cardiac fibrosis	US National Guidelines Clearinghouse on Cardiac fibrosis • NICE Guidance on Cardiac fibrosis • NHS PRODIGY Guidance • FDA on Cardiac fibrosis • CDC on Cardiac fibrosis
Textbook Information on Cardiac fibrosis	Books and Textbook Information on Cardiac fibrosis
Pharmacology Resources on Cardiac fibrosis	Dosing of Cardiac fibrosis • Drug interactions with Cardiac fibrosis • Side effects of Cardiac fibrosis • Allergic reactions to Cardiac fibrosis • Overdose information on Cardiac fibrosis • Carcinogenicity information on Cardiac fibrosis • Cardiac fibrosis in pregnancy • Pharmacokinetics of Cardiac fibrosis •
Genetics, Pharmacogenomics, and Proteinomics of Cardiac fibrosis	Genetics of Cardiac fibrosis • Pharmacogenomics of Cardiac fibrosis • Proteomics of Cardiac fibrosis
Newstories on Cardiac fibrosis	Cardiac fibrosis in the news • Be alerted to news on Cardiac fibrosis • News trends on Cardiac fibrosis
Commentary on Cardiac fibrosis	Blogs on Cardiac fibrosis
Patient Resources on Cardiac fibrosis	Patient resources on Cardiac fibrosis • Discussion groups on Cardiac fibrosis • Patient Handouts on Cardiac fibrosis • Directions to Hospitals Treating Cardiac fibrosis • Risk calculators and risk factors for Cardiac fibrosis
Healthcare Provider Resources on Cardiac fibrosis	Symptoms of Cardiac fibrosis • Causes & Risk Factors for Cardiac fibrosis • Diagnostic studies for Cardiac fibrosis • Treatment of Cardiac fibrosis
Continuing Medical Education (CME) Programs on Cardiac fibrosis	CME Programs on Cardiac fibrosis
International Resources on Cardiac fibrosis	Cardiac fibrosis en Espanol • Cardiac fibrosis en Francais
Business Resources on Cardiac fibrosis	Cardiac fibrosis in the Marketplace • Patents on Cardiac fibrosis
Informatics Resources on Cardiac fibrosis	List of terms related to Cardiac fibrosis

WikiDoc Help Menu Quick Start.. Get Started Here! How to Login How to Search Pages How to Start a New Page How to Edit a Page Cheat Sheet Editing basics Learning Basic Formatting How to make Links in WikiDoc & to External Sites How to Make Lists How to Ignoring Formatting Adding References or Footnotes to Articles Tracking Changes You Have Made How to Put an Article Into a Category When Multiple Topics Should Go To The Same Page (MI, Acute MI, AMI) Using Redirection Advanced editing How to Make Tables How to Insert Images and Other Media How to Add Video Help:How to Make Columns Web Colors How To Make Templates How to Move Pages Inserting Dynamic Dates and Times Inserting WikiDoc Statistics Editing the Table of Contents Communicating your edits Let others know what you changed: The importance of Edit Summaries Minor Edits Edit Conflicts Help Videos You Can Watch Getting Started Video