Endoreduplication

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

This article may require cleanup to meet Wikipedia's quality standards. Please improve this article if you can.

Endoreduplication is the duplication of the genome without mitosis. Endoreduplication is a common process in eukaryotes and results in an increase in the nuclear DNA content, permitting amplification of the genome of specialized cells. Moreover, the increase in the ploidy level correlates with an increase in nuclear volume and cell size, suggesting that elevated nuclear DNA content is required to maintain larger cells. In animals, endoreduplication is most frequent in Appendicularia, where endoreduplicated epithelial cells are used to produce feeding structures, and in arthropods, where the highest value of the endopolyploidy occur in the Malpighian tubules and salivary glands of various dipters. In mammals, endopolyploidy is rare and evident only in the trophoblast, decidua and myocardial cells. In contrast, endoreduplication is widespread in plants, particularly in angiosperms, and may occur in any cell types except the gametes, the meristematic and guard cells. The constant tissue-specific pattern of endopolyploidy in different organs suggest that endoreduplication cycles in plants constitute an essential part of the developmental programmes that are necessary for differentiation and for specialized function of given cells and tissues.

References

External Links:

• [1]Cebolla, A., J.M. Vinardell, E. Kiss, B. Olah, F. Roudier, A. Kondorosi and E. Kondorosi (1999) The mitotic inhibitor ccs52 is required for endoreduplication and ploidy-dependent cell enlargement in plants. Embo J. 18, 4476-4484.
• [2]Edgar, BA & Orr-Weaver, TL (2001) Endoreplication cell cycles: more for less. Cell. May 4;105(3):297-306

WikiDoc Help Menu Quick Start.. Get Started Here! How to Login How to Search Pages How to Start a New Page How to Edit a Page Cheat Sheet Editing basics Learning Basic Formatting How to make Links in WikiDoc & to External Sites How to Make Lists How to Ignoring Formatting Adding References or Footnotes to Articles Tracking Changes You Have Made How to Put an Article Into a Category When Multiple Topics Should Go To The Same Page (MI, Acute MI, AMI) Using Redirection Advanced editing How to Make Tables How to Insert Images and Other Media How to Add Video Help:How to Make Columns Web Colors How To Make Templates How to Move Pages Inserting Dynamic Dates and Times Inserting WikiDoc Statistics Editing the Table of Contents Communicating your edits Let others know what you changed: The importance of Edit Summaries Minor Edits Edit Conflicts Help Videos You Can Watch Getting Started Video

Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .