Epstein's pearls

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Epstein's pearls are small white or yellow cystic papules (1 to 3 mm in size) often seen in the median palatal raphe of the mouth of newborn infants (occur in 65-85% of newborns). They are typically seen on the roof of the mouth (palate) and are filled with fluid. They are caused during the development of the palate by entrapped epithelium (fissural cyst). They are completely harmless and do not require treatment because they resolve spontaneously over the first few weeks of life.

Similar cysts that are scattered over the hard palate are referred to as Bohn's nodules come from minor salivary glands.

Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .