Estradiol indications
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884
List of indications
Menopause: vasomotor symptoms
Menopause: symptoms of vulvar and vaginal atrophy
Hypoestrogenism
Breast cancer
Carcinoma of the prostate
Osteoporosis
Menopause: vasomotor symptoms
Estradiol Tablets, USP are indicated in the treatment of moderate to severe vasomotor symptoms associated with the menopause. Return to top
Menopause: symptoms of vulvar and vaginal atrophy
Estradiol Tablets, USP are indicated in the treatment of moderate to severe symptoms of vulvar and vaginal atrophy associated with the menopause. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered. Return to top
Hypoestrogenism
Estradiol Tablets, USP are indicated in the treatment of hypoestrogenism due to hypogonadism, castration or primary ovarian failure. Return to top
Breast cancer
Estradiol Tablets, USP are indicated in the treatment of breast cancer (for palliation only) in appropriately selected women and men with metastatic disease. Return to top
Carcinoma of the prostate
Estradiol Tablets, USP are indicated in the treatment of advanced androgen-dependent carcinoma of the prostate (for palliation only). Return to top
Osteoporosis
Estradiol Tablets, USP are indicated in the prevention of osteoporosis. When prescribing solely for the prevention of postmenopausal osteoporosis, therapy should only be considered for women at significant risk of osteoporosis and for whom non-estrogen medications are not considered to be appropriate.
The mainstays for decreasing the risk of postmenopausal osteoporosis are weight bearing exercise, adequate calcium and vitamin D intake, and when indicated, pharmacologic therapy. Postmenopausal women require an average of 500 mg/day of elemental calcium. Therefore, when not contraindicated, calcium supplementation may be helpful for women with suboptimal dietary intake. Vitamin D supplementation of 400-800 IU/day may also be required to ensure adequate daily intake in postmenopausal women. Return to top
The content of this page is taken from the FDA package insert for this drug and should not be edited.
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
