Estramustine

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Image:Estramustine.svg
Image:Estramustine-3D-vdW.png
Estramustine
Systematic (IUPAC) name
(17-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17- decahydro-6H-cyclopenta[a]phenanthren-3-yl) bis (2-chloroethyl)aminomethanoate
Identifiers
CAS number 2998-57-4
ATC code L01XX11
PubChem 18140
DrugBank APRD00625
Chemical data
Formula C23H31Cl2NO3 
Mol. mass 440.403 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 20 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

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Overview

Estramustine (Emcyt®) is a chemotherapy agent used to treat prostate cancer. It is a combination of estrogen (specifically, estradiol) and mechlorethamine, a nitrogen mustard.

External links

de:Estramustin


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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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