Ethacridine lactate
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Ethacridine lactate is an aromatic organic compound based on acridine. Synonyms include acrinol, rivanol and ethacridine monolactate monohydrate. Its formal name is 2-ethoxy-6,9-diaminoacridine monolactate monohydrate. It forms orange-yellow crystals with a melting point of 226 °C and it has a stinging smell.
Its primary use is as an antiseptic in solutions of 0.1%.
Ethacridine is also used as an agent for second trimester abortion. Up to 150 ml of a 0.1% solution is instilled extra-amniotically using a foley catheter. After 20 to 40 hours, 'mini labor' ensues. In China, an intra-amniotic method has also been used. Ethacridine as an abortifacient is found to be safer and better tolerated than 20% hypertonic saline.
References
- Obstetrics & Gynecology 1983;61:733-736
- Merck Index, 11th Ed., 3668.
External links
Antiseptics and disinfectants (D08) | |
|---|---|
| Acridine derivatives | Ethacridine lactate - Aminoacridine - Euflavine |
| Biguanides and amidines | Dibrompropamidine - Chlorhexidine - Propamidine - Hexamidine - Polihexanide |
| Phenol and derivatives | Hexachlorophene - Policresulen - Phenol - Triclosan - Chloroxylenol - Biphenylol |
| Nitrofuran derivatives | Nitrofurazone |
| Iodine products | Iodine/octylphenoxypolyglycolether - Povidone-iodine - Diiodohydroxypropane |
| Quinoline derivatives | Dequalinium - Chlorquinaldol - Oxyquinoline - Clioquinol |
| Quaternary ammonium compounds | Benzalkonium - Cetrimonium - Cetylpyridinium - Cetrimide - Benzoxonium chloride - Didecyldimethylammonium chloride |
| Mercurial products | Mercuric amidochloride - Phenylmercuric borate - Mercuric chloride - Mercurochrome - Thiomersal - Mercuric iodide |
| Silver compounds | Silver nitrate |
| Others | Hydrogen peroxide - Eosin - Propanol - Tosylchloramide sodium - Isopropanol - Potassium permanganate - Sodium hypochlorite - Ethanol |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
