Ethcathinone

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Ethcathinone
Systematic (IUPAC) name
2-ethylamino-1-phenyl-propan-1-one
Identifiers
CAS number	?
ATC code	?
PubChem	?
Chemical data
Formula	C13H15NO
Mol. mass	177.3
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	oral, intranasal

Ethcathinone (also called Ethylpropion, N-ethylcathinone and 2-ethylaminopropiophenone), is a stimulant drug. It is an active metabolite of diethylcathinone and has a stimulant effect on the CNS.

Contents 1 Pharmacology 2 Side effects 3 See also 4 References

Pharmacology

Ethcathinone is a methylphenidate-like DA/NE reuptake inhibitor (Rothman 2005). Its mechanism of action is similar to other appetite suppressants such as sibutramine, phentermine and dextroamphetamine. Chemically, it is the N-ethyl homologue of cathinone and dimethylcathinone.

Side effects

Severe

• Insomnia
• Pulmonary hypertension
• Stroke
• Psychosis

Cardiovascular

• Tachycardia, hypertension, arrhythmia, chest pain

Ear, nose, and throat

• Xerostomia, metallic taste

Endocrine

• Changes in libido, gynecomastia, menstrual irregularities

Eye

• Blurred vision

Gastrointestinal

• Nausea/vomiting, constipation, abdominal cramps

Hematological

• Bone marrow depression, agranulocytosis, leukopenia

Neurological

• Tremor

Psychological

• Euphoria, agitation, nervousness, restlessness, dizziness, anxiety, headache, mental depression, seizures

Skin

• Rash, hives, alopecia, ecchymosis

Urogenital and reproductive

• Changes in libido, impotence

See also

• Cathinone
• Diethylcathinone
• Methcathinone
• Methylenedioxymethcathinone

References

v • d • e Stimulants
Alkylamines	Cyclopentamine • Geranamine • Isometheptene • Octodrine • Propylhexedrine • Tuamine
Alphapyrrolidinylalkiophenones	α-PPP • MDPPP • MDPV • MPHP • MPPP • MOPPP • Pyrovalerone
Cholinergics	ABT-089 • ABT-418 • Anabasine • Arecoline • Cotinine • Cytisine • Dianicline • Epibatidine • Epiboxidine • GTS-21 • Ispronicline • Nicotine • Rivanicline • Tebanicline • Varenicline
Convulsants	Bicuculline • Gabazine • Pentetrazol • Picrotoxin • Strychnine • Thujone
Eugeroics	Adrafinil • Armodafinil • Carphedon • Modafinil
Phenethylamines	4-Fluoroamphetamine • 4-Fluoromethamphetamine • 4-Methylmethcathinone • 4-MTA • Aletamine • Amphechloral • Amphetamine (Dextroamphetamine, Adderall) • Amphetaminil • Benzphetamine • Bupropion • Cathinone • Chlorphentermine • Clenbuterol • Clobenzorex • Clortermine • Diethylpropion • Dimethoxyamphetamine • Dimethylamphetamine • Dimethylcathinone • Ephedrine • Epinephrine • Ethcathinone • Ethylamphetamine • Fenethylline • Fenfluramine • Fenproporex • Furfenorex • Levomethamphetamine • Lisdexamfetamine • MDMA • Mefenorex • Methamphetamine • Methcathinone • Methoxyphedrine • Methylone • Octopamine • Parahydroxyamphetamine • PMA • PMEA • PMMA • PPAP • Phendimetrazine • Phenmetrazine • Phentermine • Phenylephrine • Phenylpropanolamine • Propylamphetamine • Pseudoephedrine • Selegiline • Synephrine • Xylopropamine
Phenylaminooxazoles	4-Methyl-aminorex • Aminorex • Clominorex • Fenozolone • Fluminorex • Pemoline • Thozalinone
Piperazines	2C-B-BZP • BZP • GBR-12783 • GBR-12935 • GBR-13069 • GBR-13098 • GBR-13119 • MeOPP • MBZP • Vanoxerine
Piperidines	2-Benzylpiperidine • Desoxypipradrol • Ethylphenidate • (-)-Methyl-1-methyl-4β-(2-naphthyl)piperidine-3β-carboxylate • Methylphenidate (Dexmethylphenidate) • Nocaine • Phacetoperane • Pipradrol
Tropanes	3-Pseudotropyl-4-fluorobenzoate • Altropane • Brasofensine • CFT (WIN 35,428) • β-CIT (RTI-55) • Cocaethylene • Cocaine • β-CPPIT • Dichloropane (RTI-111) • FE-β-CPPIT • FP-β-CPPIT • PIT • PTT • RTI-32 • RTI-113 • RTI-121 (IPCIT) • RTI-336 • Tesofensine • Troparil (β-CPT, WIN 35,065-2) • WF-23 • WF-33
Xanthines	Caffeine • Aminophylline • Paraxanthine • Theobromine • Theophylline
Others	Amineptine • Bemegride • Benzydamine • BPAP • BTQ • Clofenciclan • Cypenamine • Cyprodenate • Diclofensine • Dimethocaine • Diphenyl prolinol • Ethamivan • Fencamfamine • Feprosidnine • Gilutensin • GYKI-52895 • Hexacyclonate • Indanorex • Indatraline • LR-5182 • Mazindol • Mesocarb • Naphthylisopropylamine • Nikethamide • Nomifensine • Phthalimidopropiophenone • Prolintane • Sibutramine • Yohimbine • Zylofuramine
See also Sympathomimetic amines