Ethionine
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| Ethionine | |
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| Image:Ethionine.png | |
| IUPAC name | 2-Amino-4-ethylsulfanylbutyric acid |
| Other names | S-Ethyl-L-homocysteine |
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| CAS number | |
| PubChem | |
| SMILES | CCSCC[C@@H](C(=O)O)N |
| Properties | |
| Molecular formula | C6H13NO2S |
| Molar mass | 163.239 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references | |
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Ongoing Trials on Ethionine at Clinical Trials.gov Clinical Trials on Ethionine at Google
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US National Guidelines Clearinghouse on Ethionine
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Patient resources on Ethionine Discussion groups on Ethionine Directions to Hospitals Treating Ethionine Risk calculators and risk factors for Ethionine
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Overview
Ethionine is a non-proteinogenic amino acid structurally related to methionine, with an ethyl group in place of the methyl group.
Ethionine is an antimetabolite and methionine antagonist. It prevents amino acid incorporation into proteins and interferes with cellular use of adenosine triphosphate (ATP). Because of these pharmacological effects, ethionine is highly toxic and is a potent carcinogen.[1]
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
