Etidronic acid
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| Etidronic acid
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| Systematic (IUPAC) name | |
| (1-hydroxy-1-phosphono-ethyl)phosphonic acid | |
| Identifiers | |
| CAS number | |
| ATC code | M05 M05BB01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C2H8O7P2 |
| Mol. mass | 206.028 g/mol |
| Pharmacokinetic data | |
| Bioavailability | 3% |
| Metabolism | Nil |
| Half life | 1 to 6 hours |
| Excretion | Renal and fecal |
| Therapeutic considerations | |
| Licence data |
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| Pregnancy cat. |
C(US) |
| Legal status |
℞ Prescription only |
| Routes | Oral, intravenous |
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Ongoing Trials on Etidronic acid at Clinical Trials.gov Trial results on Etidronic acid Clinical Trials on Etidronic acid at Google
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US National Guidelines Clearinghouse on Etidronic acid NICE Guidance on Etidronic acid
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Etidronic acid (INN) or etidronate disodium (trade name Didronel®) is a bisphosphonate used to strengthen bone, treat osteoporosis, and treat Paget's disease of bone.
Chelating Agent and Anti-oxidant
Etidronic acid is a chelating agent and may be added to bind or, to some extent, counter the effects of substances, such as arsenic, iron, or other metal ions (that can occur in the presence of some soaps), which may be discharged as a component of grey wastewater and could conceivably contaminate groundwater supplies. Etidronic acid also acts to retard rancidification and oxidation of fatty acids. While etidronic acid has not been limited from inclusion in cosmetics and does have legitimate uses, it is recommended that, as with most cosmetic products (particularly soaps), the product should be thoroughly rinsed from the skin after use.
Etidronic acid is listed as an ingredient of several cosmetic formulations. Several examples of Etidronic acid's presence in soap products are: Propolis soap, Dove body wash, Axe body wash, Lever 2000 body wash, Yardley of London, Johnson and Johnson's Lavender, Chamomile Creamy Baby Soap bar and Tesco Pure Soap bar.
Etidronic acid is also included among swimming pool chemicals. It is used as a stain inhibitor to prevent metal ions coming out of solution and staining the sides of swimming pools.
Drugs for treatment of bone diseases (M05) | |
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| Bisphosphonates | Nitrogenous (Pamidronic acid, Alendronic acid, Ibandronic acid, Risedronic acid, Zoledronic acid) - Non-nitrogenous (Etidronic acid, Clodronic acid, Tiludronic acid) |
| Bone morphogenetic proteins | Dibotermin alfa - Eptotermin alfa |
| Other | Ipriflavone - Aluminium chlorohydrate - Strontium ranelate |
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

