Fibrinoid necrosis
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Fibrinoid necrosis is a type of necrosis that can be seen in the walls of small or medium-sized muscular blood vessels (it does not involve arterioles, capillaries, or venules <-this fact should be checked by an expert; page 19 of 2nd edition golljan says "small muscular arteries, arterioles, venules, and glomerular capillaries"). It is associated with immune-complex vasculitis (primary inflammation of vessels), and hypertenstion. Fibrin deposition occurs in damaged necrotic vessel walls. Histologically, the damaged tissue will have a bright pink, fibrin-like quality, which gives this process its name.
Malignant hypertension and polyarteritis nodosa are common causes.[1]
References
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Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
