Flurbiprofen
You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.
| Image:Flurbiprofen.svg | |
| Flurbiprofen
| |
| Systematic (IUPAC) name | |
| 2-(3-fluoro-4-phenyl-phenyl)propanoic acid | |
| Identifiers | |
| CAS number | |
| ATC code | M01 M02AA19, S01BC04 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C15H13FO2 |
| Mol. mass | 244.261 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | > 99% |
| Metabolism | Hepatic (CYP2C9) |
| Half life | 4.7-5.7 hours |
| Excretion | Renal |
| Therapeutic considerations | |
| Pregnancy cat. | |
| Legal status | |
| Routes | Oral |
Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. It is also known by the trade name ANSAID and marketed by Pfizer.
Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges.
R-flurbiprofen is the single enantiomer of racemate flurbiprofen; this compound is currently in clinical trials for the treatment of metastatic prostate cancer, and Alzheimer's disease.
Flurbiprofen was mocked by television satirist Stephen Colbert (for its unlikely name) during an interview with Terry Gross aired on October 9, 2007 on National Public Radio's program "Fresh Air." Colbert had been taking the drug after breaking his wrist earlier that year.
Topical products for joint and muscular pain (M02) | |
|---|---|
| Anti-inflammatory preparations, non-steroids | Butylpyrazolidines: Phenylbutazone - Mofebutazone - Clofezone - Oxyphenbutazone
Propionic acid derivatives: Tolmetin - Diclofenac - Fentiazac other: Benzydamine - Etofenamate - Piroxicam - Felbinac - Bufexamac - Ketoprofen - Bendazac - Naproxen - Ibuprofen - Feprazone - Niflumic acid - Meclofenamic acid - Flurbiprofen - Suxibuzone - Indometacin - Nifenazone |
| Other | Tolazoline - Dimethyl sulfoxide |
