Thyroid epithelial cell

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Thyroid epithelial cell

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Overview

Section of thyroid gland of sheep. X 160. ("Cubical epithelium" labeled at center left.)
Section of thyroid gland of sheep. X 160. ("Cubical epithelium" labeled at center left.)

Thyroid epithelial cells (also called follicular cells or principal cells) are cells in the thyroid gland which produce and secrete thyroxine (T4) and triiodothyronine (T3).

They are simple cuboidal epithelium[1] and are arranged in spherical follicles surrounding colloid.

They have thyrotropin receptors on their surface, which respond to thyroid-stimulating hormone.

Embryologic origin is from endoderm (in contrast to parafollicular cells, below).

Relationship to other cell types

Calcitonin-producing parafollicular cells (C cells) can be found scattered along the basement membrane of the thyroid epithelium. Embryologic origin is from neural crest cells.

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Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

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