Fox-Fordyce disease
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| Fox-Fordyce disease Classification and external resources | |
| ICD-10 | L75.2 |
|---|---|
| ICD-9 | 705.82 |
| DiseasesDB | 30029 |
| eMedicine | derm/160 |
| MeSH | D005588 |
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Fox-Fordyce disease is a chronic blockage of the sweat gland ducts with a secondary, nonbacterial inflammatory response to the secretions and cellular debris in the cysts. Hidradenitis is very similar but tends to have a secondary bacterial infection so that pus-draining sinuses are formed. It is a very devastating skin disease that does not have universally curative treatments.
Eponym
It is named for George Henry Fox and John Fordyce.[1][1]
Treatment
The mainstay treatment is surgical removal of the skin tissue containing affected sweat glands. Irradiation therapy may also be used and antibiotics are used to reduce the inflammatory response.
No treatment is required for Fordyce granules, except for cosmetic removal of labial lesions. Inflamed glands can be treated topically with clindamycin. When surgically excised, recurrence does not occur. Neoplastic transformation is very rare but has been reported.
References
External links
- http://www.wdxcyber.com/nvulva03.htm
- http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=271470151
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
